Studying new methods to observe and control electrophysiological signaling #ucdavisresearch
Davis, CA
Joined January 2019
- Tweets49
- Following132
- Followers180
- Likes90
Sack-Yarov Lab retweeted
Excited to share the new paper co-authored with @VorobyovUCD, @clancyatheart, @sackyarov, @Kazu_Furutani entitled "Structural modeling of the hERG potassium channel and associated drug interactions" frontiersin.org/articles/10.โฆ
Sack-Yarov Lab retweeted
Excited to share a preprint describing our research progress on designing novel therapeutics to treat pain funded by the NIH HEAL Initiative. #nihHEALinitiative #ucdavis #UCDavisMed #ucdavishealth #pain #OpioidCrisis biorxiv.org/content/10.1101/โฆ
Sack-Yarov Lab retweeted
Mechanism of use-dependent Kv2 channel inhibition by RY785 rupress.org/jgp/article/154/โฆ Nice paper from the @sackyarov lab!
Sack-Yarov Lab retweeted
๐จ Check out this work from Department Faculty @sackyarov! ๐จ
A Kv2 inhibitor traps itself in place. Our latest Research News highlights study (bit.ly/36rFYuE) from Matthew James Marquis and Jon T. Sack @sackyarov: bit.ly/3KK7EsM
Sack-Yarov Lab retweeted
Marquis & Sack @sackyarov (bit.ly/36rFYuE) show that voltage activation, but not channel opening, is required for RY785 to access the central cavity of Kv2 channels, where it promotes voltage sensor deactivation to trap itself in place bit.ly/3KK7EsM
Sack-Yarov Lab retweeted
Congratulations to Dr. John Dawson from @UCD_BPH & @ucd_physiology, who has been working with me, Prof. Colleen Clancy @clancyatheart and Prof. Yarov-Yarovoy @sackyarov! John conferred Ph.D. degree in Biophysics in May and had a great exit seminar today!
Sack-Yarov Lab retweeted
A Kv2 inhibitor traps itself in place. Our latest Research News highlights study (bit.ly/36rFYuE) from Matthew James Marquis and Jon T. Sack @sackyarov: bit.ly/3KK7EsM
Sack-Yarov Lab retweeted
Image shows how RY785 modifies gating currents. Marquis and Sack @sackyarov show mechanism of use-dependent Kv2 channel inhibition by RY785. bit.ly/36rFYuE
#Biophysics #MolecularPhysiology #MolecularPharmacology
Sack-Yarov Lab retweeted
Marquis & @sackyarov bit.ly/36rFYuE show that voltage activation, but not channel opening, is required for RY785 to access the central cavity of Kv2 channels, where it promotes voltage sensor deactivation to trap itself in place. In Research News: bit.ly/3KK7EsM
Sack-Yarov Lab retweeted
Honored and grateful to host the incredible @NiengYan for the @ucdavis Tracy and Ruth Storer Lectureship in the Life Sciences this week! @ucdavisbiology @UCDavisHealth @ucd_physiology @UCDAVISPharmac1 @sackyarov
Sack-Yarov Lab retweeted
Matthew James Marquis and Jon Sack @sackyarov show that the use-dependent inhibition of Kv2.1 by RY785 is consistent with gated access to a cavity within the channel that traps RY785. bit.ly/36rFYuE
#Biophysics #MolecularPhysiology #MolecularPharmacology
Sack-Yarov Lab retweeted
Graduate Studies announced the first cohort of the Faculty Academy of Graduate Student Well-Being, which trains faculty to teach seminars on mental health and well-being to grad students. Learn about this innovative program and its participants: ow.ly/qtj550G5R6U
#UCDavis
Sack-Yarov Lab retweeted
We are SO deeply grateful to Dr. Rabaud for her purposeful and persistent work with @MCIPUCD and now also @UCD_BPH Thanks Nicole for sharing your inspiring story and for your long lasting impact on improving the graduate student (and faculty) experience!
When Nicole Rabaud, Ph.D. '02 was a first-generation student pursuing her Ph.D., she felt lost. Now, as director of @ucdavisbiology grad programs, she uses her #FirstGen perspective to help grad students feel like they belong. Read her story: ow.ly/sE0p50FhPa8
ALT Headshot of Nichole Rabaud inside her office.
Sack-Yarov Lab retweeted
We are making an exciting progress! #NIH #nihHEALinitiative @NINDSNews @NIHPainResearch #scientists at @UCDavisMed are using computational biology to engineer a tarantula venom #peptide into a non-opioid treatment for #chronicpain. #NIH #nihHEALinitiative heal.nih.gov/news/stories/prโฆ
We are making an exciting progress on our NIH HEAL Initiative research project! heal.nih.gov/news/stories/prโฆ
Sack-Yarov Lab retweeted
I hope to see not only reflection, but also action and change @ucdavis. @MCIPUCD @UCDavisBMEGG @UCD_BPH @PTXatUCD #StrikeforBlackLives #ShutDownSTEM #ShutDownAcademia #BlackLivesMatter
The @GradSchoolSinai @IcahnMountSinai SUPPORTS #ShutDownStem! Tomorrow, June 10th, and EVERY DAY, take a moment to reflect on the changes that we can make to further equality and healing. We hope you will JOIN US! #Strike4BlackLives #ShutdownAcademia #BlackLivesMatter
Sack-Yarov Lab retweeted
I've recievced many calls and emails from colleagues asking for advice on what to do. Twitter isn't optimal, but I have grants and papers to get done, so this will have to do. In anticipation of this planning meeting... some concrete agenda items. 1/n shutdownstem.com/
Sack-Yarov Lab retweeted
For those who are interested in research-based solutions to stop police violence, hereโs what you need to know - based on the facts and data. A thread. (1/x)
The Yarov-Yarovoy Lab is still going strong on the last day of #bps2020! Stop by B416 and hear about our work! @rosettaathome @BiophysicalSoc #bps20 @UCDavisResearch @UCDavisMed
