⚽️ I’m having WAY too much fun with this game on the iPhone Duo 😂 This is how you take advantage of a foldable! 🥅 The goalie is on the vertical screen ⚽️ You kick the ball using the bottom screen 📱 The entire form factor becomes part of the game! It genuinely feels like we’re back in the Wild West of apps, when developers made fun, creative experiences just for the sake of having FUN. We need more of this!! 🔥

I absolutely love that the @AppStore allows us to have animated headers!

While I was writing this, my AI assistant got cut off by a bio safety filter. It was summarizing my own team's notes on the model we released today 😅 Frontier labs are moving fast into biology but the scientists and clinicians who'd get the most out of these models are unfortunately the ones running into walls like this one (and every day). So we partnered with TIGEM (Telethon Institute of Genetics and Medicine), Naple "Federico II" University and Zhongguancun Academy to train Carbon-X. Carbon-X is an open 14B model that reads raw DNA and talks about it in plain English. On our DNA benchmarks it scores 67%, vs 61% for Claude Opus 5.5 and 50% for Gemini 4 Argon, and its within a point of GPT-6.1 Sol at about 1000x lower cost. We kept human and animal viruses out of the training data. The weights are open and the model runs on hardware accessible to academia (a laptop). One example from the blog: give frontier models an 8kb stretch of the NF1 gene with a mutation at a splice site. Most of them call it benign, refuse, or run out of tokens. Carbon-X says pathogenic, because the mutation breaks the splice site. This century, biology may be where AI matters most. We want to get there with the safety work done in the open and every lab in the world able to build on it. Go try it, and tell us what you find. Model: huggingface.co/HuggingFaceBi… 
Blog: huggingface.co/spaces/Huggin…

It's been a lot of fun trying the Duo out for a week, but it feels like I've gotten to use an extraordinarily polished prototype — not a finished product that I'd want to buy and carry. daringfireball.net/2026/10/t…

Happy Trafalgar Day Never mind maneuvers Go straight at ‘em

Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERN’s record by a factor of 10. Last week, we enriched isotopes in the world’s most powerful plasma centrifuge, beating the Soviet record that stood for 40 years. Now, we’re building a fusion reactor in San Francisco to achieve record power density.

In the process, we can emulate our ancestors, and build a new Metroland that lets people live and thrive in a green belt in which the best and most beautiful land is preserved and protected just as strongly as today. Please give the report a read cps.org.uk/research/the-futu…

People who cured / are curing their own cancer on X: 1/ @sytses - bone cancer, billionaire founder of Gitlab, developed 10+ personalized therapies for himself. 2/ @paul_conyngham - shrank his dog Rosie's mast cell cancer tumors after chemo and surgery weren't enough. Now backed by YC and Founders Fund 3/ @miriamgonp - stage 4 breast cancer, tumor sequenced, searching for vaccine manufacturer now 4/ @kevinace - stage 4 lung cancer, angel investor in 300+ companies, first drug stopped working after 18 months. Vaccine designed, now paying $300k out of pocket for the vaccine 5/ @masonbgrant: going founder mode on his his 32-year-old wife's rare liver cancer, sequencing her tumor with AI agents 6/ @ArunRLverma: former product leader at Atoms and Shopify, brain tumor, built a vaccine from his tumor. Now building an AI health agent startup based on what he went through We're going to make it

I spend a lot of time, perhaps too much, thinking about the lost architecture of Britain. Crystal Palace was the most tremendous loss of the modern era, yet it's rare to see any pictures of it. When built in 1851, it was the largest building in the world and three times the size of St Paul's Cathedral. What's more, that immense ironwork and 293,000 glass panels went up in just 190 days for the World's Fair. Almost 1 million square feet of glass. An extraordinary feat. It was razed in a fire in the 1930s and never rebuilt.

Claude Code and I have turned my ancient Kindle into cool family photo frame for my film photos (see pinned post in profile). To prevent Kindle from downloading the latest update and overwriting its OS, cheeky Claude filled it up with empty files so the updated doesn’t get through. And now… I have my personal stylish black and white photo frame with family pics

Claude isn't a great musician (yet) But this kind of video would be unfathomable to make even 6 months ago with previous LLMs "Claudia Explains: Euclid"

The Ferrari CEO praised @Tesla's new Roadster unveil today: "It ​certainly shows that in the automotive world there's ​still ⁠a lot to be done. We have to keep dreaming. As a European, thank you for showing us how that, even in an old ⁠world, ​you can still innovate and dare." He gave the Roadster launch 10 out of 10 for technology and 10 out of 10 for presentation.

Nvidia CEO Jensen Huang to Chancellor Merz: I've also heard you say that you want to find that balance between innovation and regulation. There's nothing to regulate if the industry doesn't thrive.