Robert Dickson retweeted
We did it!
Absolutely thrilled to share the results of the ASPEN trial published today in @NEJM
Brensocatib(10mg and 25mg vs placebo) reduced exacerbations over 52 weeks and slowed lung function decline
A new treatment for bronchiectasis patients
nej.md/4lBHwUr
Robert Dickson retweeted
Come learn to study the lung microbiome at ATS 2025! Meet and learn from an all-star team of experts. San Francisco, May 16th.
Robert Dickson retweeted
This man from the Middle Ages had a knife hand as a prosthetic
Thread 🧵 on the Germanic man with a knife for an arm and how we know
Robert Dickson retweeted
Not even the craziest part of that language family
Robert Dickson retweeted
Tomorrow's Grand Rounds will feature Dr. Robert Dickson, MD, (@robertpdickson) of @umichmedicine, presenting “The Role of the Microbiome in Critical Illness" virtually and in-person. Join us!
Details: medicine.wisc.edu/department…
Robert Dickson retweeted
Ryan Day is now 45-1 against Big Ten teams that aren't Michigan, and 1-4 against Big Ten teams that are Michigan
Robert Dickson retweeted
According to dynamical systems, psychiatric disorders can be seen as energy landscapes with peaks and valleys. OCD has deep valleys where neural activity gets stuck, while schizophrenia has shallow valleys that let neural activity roam too freely, connecting unrelated ideas.
Robert Dickson retweeted
My kid and his friends went as Tally Hall and ran into the _actual_ @shaneMauX! This is winning Halloween in Ann Arbor.
Robert Dickson retweeted
Here’s a timeline of my career
Orange=grants submitted
Green=grants funded
Lessons learned?
-persistence pays
-scientist=professional writer
-grant writing makes the science better
-scientist=entrepreneur. Not every “invention” is a hit (learned this from @ABCSharkTank)
Robert Dickson retweeted
In contrast, in college football's top division, 134 teams play zero exhibition games, 12 regular season games, and compete for 102 trophies they made up themselves, not counting the conference, bowl, and playoff trophies. (2/7)
Robert Dickson retweeted
I've seen claims online that tardigrades can live for 30 years without food or water. A Nat Geo article says this, without attribution.
My initial reaction was that this must be an estimate. Why would anyone wait 30 years to figure this out? But Japanese scientists actually did.
In 2015 or so, researchers at the National Institute of Polar Research, in Tokyo, looked inside a freezer and found some old moss samples that had been collected from Antarctica in 1983. The moss had been stuffed into a plastic bag and then stored at -20 °C for the last 30.5 years.
The researchers slowly thawed the moss and then rehydrated it. They found two living tardigrades and one tardigrade egg. At first, the animals moved really slowly, but then they moved a lot more after a few days and started eating algae.
One of the tardigrades later laid eggs and reproduced. The other tardigrade died without reproducing. The egg also hatched and those offspring reproduced, too. The tardigrades seem to survive because they shut down their metabolisms and have proteins that protect their DNA from oxidative reactions over decades.
So, in this case, an internet claim that sounds made up is actually true.
Paper: doi.org/10.1016/j.cryobiol.2…
Robert Dickson retweeted
Replying to @CritCareReviews @NEJMEvidence @CIHR_IRSC @InnovationCA @ACTAEC @khome @ogradyhk @CCCTG_ @CritCareSociety @SRSMcMasterU @machealthsci @McMasterU @ResearchStJoes
Critically ill muscle isn’t programmed for exercise, it’s programmed to support immune defences and it isn’t in its usual phenotype, exercise doesn’t have the usual effect - deliberate muscle catabolism. Hopefully @Zudin_P can lead us to the answers!
Robert Dickson retweeted
As soon as you conceptualize critical illness myopathy as a form of end-organ failure, negative trials of aggressive ICU nutrition and mobilization make more sense. It’s not caused by insufficient calories/exercise.
Like giving lasix for sepsis-induced AKI. Missing the point.
Robert Dickson retweeted
Great study from the group of @robertpdickson 👇👇showing a relationship between the microbiome and chronic rejection after lung transplantation.
I’m starting to think there might actually be something to this whole microbiome thing 😂 – at Aspen, CO
The Lung Microbiome Predicts Mortality and Response to Azithromycin in Lung Transplant Recipients with Chronic Rejection
🔗 tiny.cc/c2rcyz
Robert Dickson retweeted
🌟 Meet Dr. Chanderraj, our PITB #highlight for June 2024, & learn about his research and interesting hobby!
Check out his work on mortality in #sepsis in patients treated empirically with #cefepime vs. piperacillin-tazobactam ⏬️
Robert Dickson retweeted
Viewpoint from @robertpdickson and @RepDebDingell discusses the death of a patient caused by unregulated biological products and efforts to encourage federal government oversight of such products. ja.ma/3KjTBwi
Robert Dickson retweeted
What if there was an antibiotic that doesn't disrupt the gut microbiome?
There is now.
A discovery published @Nature today
nature.com/articles/s41586-0… @PaulHergie and colleagues @UofIllinois @justsaysinmice
Robert Dickson retweeted
Most viewed in the last 7 days from @JAMAInternalMed:
Study compares the administration of piperacillin-tazobactam compared with cefepime among patients with suspected sepsis and no clear indication for antianaerobic coverage.
ja.ma/4bmYel6
Robert Dickson retweeted
**Gut bacteria control the thermostat**
Both in sepsis and in health, body temperature is modulated by the gut microbiome.
New translational study from from our lab in the Blue Journal: tinyurl.com/4t4569a5
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