Chemistry Research Investigator @Incyte | Postdoc @NarayanLab @UMLifeSciences (2019-22) | Ph.D. from @GroupTakacs @unlchemistry (2013-19) | š³ļøāš (he/him) |
Wilmington, DE
Joined September 2016
- Tweets75
- Following423
- Followers171
- Likes2.3K
Suman Chakrabarty retweeted
Go Biocatalysis Go! Congratulations to @EvanORomero, @AtsauSaucedo, @joserhern1, @DiYang33319166, and @purfectcatalyst on this perspective about the adoption of biocatalysis in organic chemistry! Make sure to check it out! pubs.acs.org/doi/10.1021/jacā¦ #GoBlue #BioCats
Suman Chakrabarty retweeted
P450s do fantastic chemistry, but can present practical challenges. In work just published in ACS Chemical Biology, Lara and ā¦@purfectcatalystā© create fusions of a P450 with a reductase to give a self-sufficient enzyme for oxidative biaryl coupling pubs.acs.org/doi/10.1021/acsā¦
Today marked my last day as a postdoc in the @NarayanLab! I am beyond grateful for all the learning, accomplishments and friendships. Thank you @AlisonNarayanUM and @NarayanLab for everything!! ā at Ann Arbor, MI
Suman Chakrabarty retweeted
The Transformative Power of Biocatalysis in Convergent Synthesis @UMichResearch @UMich @MichiganChem @AlisonNarayanUM @NarayanLab #JACSPerspective #Biocatalysis #Convergent #Synthesis pubs.acs.org/doi/10.1021/jacā¦
Suman Chakrabarty retweeted
The latest from twitterless Lara and @purfectcatalyst => Putting enzymes at the center of a synthesis in @J_A_C_S
#biocatalysis
@NarayanLab @UMLifeSciences @MichiganChem
The Transformative Power of Biocatalysis in Convergent Synthesis pubs.acs.org/doi/10.1021/jacā¦
Suman Chakrabarty retweeted
#Biocatalytic oxidative cross-coupling reactions for biaryl bond formation by Lara Zetzsche, @JYazarians, @purfectcatalyst, @MHinze_PhD, @laurenammurray, @AprilLukowski, @leoajoyce, @AlisonNarayanUM at @NarayanLab @MichiganChem @UMLifeSciences in @Nature nature.com/articles/s41586-0ā¦
Suman Chakrabarty retweeted
A huge thank you to @gomobel for covering recent work from @NarayanLab on #biocatalytic biaryl bond formation in @cenmag and to @fryania for her perspective on this science
@UMLifeSciences @MichiganChem
a new enzyme designed by @NarayanLab catalyses the formation of biaryls š¤©
this method offers unprecedented selectivity, āa unique case in biocatalysis,ā says @fryania
enjoy my latest story for @cenmag: cen.acs.org/synthesis/biocatā¦
art by Rajani Arora
#realtimechem @Nature
Suman Chakrabarty retweeted
In Nature this week: Enhanced enzyme ā Engineered biocatalyst offers efficient way to form biaryl compounds go.nature.com/3C8DVHf
Suman Chakrabarty retweeted
#ICYMI: Research from the @NarayanLab is featured on @Nature's cover this week.
Co-first author Lara Zetzsche describes the study as
"a proof of concept" showing that enzymes can be engineered to do a variety of reactions to build complex compounds.
nature.com/nature/volumes/60ā¦
ALT Image of the cover of Nature, with a quote from Lara Zetzsche: "This study is a proof of concept, showing that we can take enzymes in nature that naturally put together only two similar molecules, and we can ask them to do a whole host of different reactions to form the building blocks of complex compounds."
Suman Chakrabarty retweeted
New research featured on the cover of @Nature, led by @MichiganChem and @UMLifeSciences faculty member Alison Narayan, demonstrates that enzymes found in nature can be engineered to form a common building block at the core of many medicines and materials. myumi.ch/bRDAx
ALT Quote from U-M Faculty Member Alison Narayan: "Most enzymes have evolved over millions of years to perform one very specific reaction, very well. The challenge is to coax them into performing the reactions that we want to do, not just the ones theyāve evolved to do."
Very proud to to share our work on āBiocatalytic oxidative cross-coupling reactions for biaryl bond formationā now out @Nature ! Congratulations to everyone involved!!
Today, I am delighted to share work from @NarayanLab on biocatalytic oxidative cross-coupling reactions to form tetra-ortho-substituted biaryl bonds in @Nature
nature.com/articles/s41586-0ā¦
Suman Chakrabarty retweeted
Congratulations to @UMich faculty member @AlisonNarayanUM, who has received the Arthur C. Cope Scholar Award for excellence in organic chemistry.
"The Narayan group has had an enormous impact at the nexus of synthetic chemistry and enzymology."
myumi.ch/lxOvD
Suman Chakrabarty retweeted
#Outlook by @AlisonNarayanUM & co-workers @UMLifeSciences
With advances in enabling technologies, biocatalysis has transcended early applications in fermentation to have an expanding footprint as an essential tool in the production of high value compounds: bit.ly/2UvmMFQ
Suman Chakrabarty retweeted
Tune in today for the #NaturalProduct #TotalSynthesis Accounts of Chemical Research journal club, 3 PM EST
Registration is free: connect.acspubs.org/ARJournaā¦
Talks from @sarah_reisman, Tom Maimone, Tanja Gaich, @ThomasBPoulsen, and me representing @NarayanLab
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Suman Chakrabarty retweeted
In @ScienceMagazine this week @GBD_Lab slips boron into alkyl ethers through a fascinating handoff from zinc to nickel science.sciencemag.org/conteā¦
Suman Chakrabarty retweeted
These selfies of NASA's Mars helicopter with the Perseverance rover are just amazing dlvr.it/RxCKQt
Suman Chakrabarty retweeted
Two bots, one selfie. Greetings from Jezero Crater, where Iāve taken my first selfie of the mission. Iām also watching the #MarsHelicopter Ingenuity as it gets ready for its first flight in a few days. Daring mighty things indeed.
Images: go.nasa.gov/2RaUBKF
Suman Chakrabarty retweeted
An unexpected mechanism for C-F bond activationš¤ In collaboration with @GavinCTsui (CUHKšš°), we report an experimental and computational study of Pd-catalyzed SuzukiāMiyaura cross-coupling of difluoroalkenes @ACSCatalysis pubs.acs.org/doi/full/10.102ā¦
Suman Chakrabarty retweeted
Great way to start a Monday morning! Pleased to share the publication of, "Structural Diversification of Hapalindole and Fischerindole Natural Products via Cascade Biocatalysis" pubs.acs.org/doi/10.1021/acsā¦ @UMLifeSciences @UMichPharmacy @NSFCCHF @houk1000
What started off as a lunch discussion in the GRC Organometallic Chemistry in 2017 led to an awesome collaboration between @GroupTakacs and @pengliu_group in elucidating the mechanism of tertiary C-B bond formation through directed catalytic asymmetric hydroboration. @J_A_C_S
check out our latest @J_A_C_S paper with @GroupTakacs on how conformationally flexible TADDOL ligands promote challenging bond formations in catalytic alkene hydroboration. Congrats @HuilingShao @purfectcatalyst š špubs.acs.org/doi/10.1021/jacā¦
