
Staff Scientist at FZ Jülich @SachseGroup Enjoy cold microscopy, fancy pixels and loud music. Zerforschen!
Jülich, Deutschland
Joined May 2018
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my band SSB dropped a new EP today. Let me know what you think :) open.spotify.com/intl-de/alb… #SheSaidBattlecatNotSingleSideBand
New research from our lab! nature.com/articles/s41467-0… Atg18 oligomer organization in assembled tubes and on lipid membrane scaffolds
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Cryo-EM instrument scientist fz-juelich.de/de/karriere/st…
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Postdoc Position – Method development of cryogenic 4D-STEM imaging fz-juelich.de/de/karriere/st…
Cryo correlative light and electron microscopy (CLEM). #b3d cover suggestion for Bioprotocols 2023
We tried to measure #CryoEM ice thickness via @CryoSolWorld VitroJet. Excited about your feedback on biorxiv.org/content/10.1101/…
Interested in doing #CryoEM in NRW/Germany? Join my talk next wednesday at @ruhrunibochum @grk2341 to learn how you may solve your structure at ER-C @fz_juelich kalender.biologie.ruhr-uni-b…
Learning AutoScriptTEM and fascinated by having Titan Krios in a Python shell. Deep dark thoughts: SI units are great and intuitive, but what happens when I forget the e-6 for defocus?
new paper: "ATP binding and ATP hydrolysis in full-length MsbA monitored via time-resolved Fourier transform infrared spectroscopy"
doi.org/10.1515/hsz-2023-012…
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Ernst Ruska Centre featured in Biophysical Society TV youtube.com/watch?v=34PglAv2…
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🚨NEWS ALERT🚨I am starting my lab at @fz_juelich to study mitochondrial membrane proteins and I’m recruiting PhD students! Please apply/RT/contact me if you have questions. PhD Position – Cryo-EM of mitochondrial membrane protein complexes fz-juelich.de/en/careers/job…
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EMPIAR.org/EMPIAR-11034 shows scanning transmission electron microscopy (STEM) using the integrated differential phase contrast mode known as iDPC–STEM applied to a cryo-EM specimen by @SachseGroup @fz_juelich. Published @naturemethods doi.org/10.1038/s41592-022-0…). #EMPIAR #cryoEM
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Model building with a fluff. She's concerned about the correct conformations though. #guineapiginscience #cryocarrot #cryoEM #ribosomes
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The Sachse lab advent calendar is back! We will post a festive/jolly/strange EM picture every day until Xmas!🎄✨ 1/24
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Our iDPC-STEM manuscript is now published in Nature Methods doi.org/10.1038/s41592-022-0… We used scanning transmission electron microscopy to resolve vitreous cryo samples of TMV and KLH to resolutions of 3.5 and 6.5 Ang. 1/4
Our most recent Atg18 preprint is now available on BioRxiv!
New research from our lab! We elucidated how Atg18 oligomers form structural scaffolds for membrane interaction. Lots of #CryoEM structures (Helical assemblies, SPA, subtomo) suggest a conserved interaction motif for Atg18-Atg2
biorxiv.org/content/10.1101/…

















