
Breast Medical Oncology and APD @baystatehemeonc| Interested in hereditary/familial cancers and medical education
Springfield, MA
Joined March 2016
- Tweets755
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Prarthna Bhardwaj retweeted
Woke up today to news of flying cars but am still using the fax machine at work
The future remains tantalizingly out of reach
Prarthna Bhardwaj retweeted
Pick any medical specialty other than your own. Who’s the most famous physician in it? You probably can’t name one.
Almost none of us will be known outside our field, and even those who achieve real professional fame are mostly forgotten within a few decades.
Fame is a poor reason to devote your life to medicine. The work itself matters more: caring for patients, discovering new knowledge, and teaching the next generation.
Prarthna Bhardwaj retweeted
Important / sobering @JCOOP_ASCO on the business of cancer care
- Private equity or pharma-linked corps own > 20% of cancer care in many states
- global variation in drug prices are political not econ choices
- Ask your MD who they really work for!
ascopubs.org/journal/op
Prarthna Bhardwaj retweeted
Very thoughtful article. Academic medicine needs to figure out how to right the ship. More talent are leaving academics for private or industry opportunities. The question to ask now is, “Does prestige of academics even matter to the new generation? opmed.doximity.com/articles/…
Prarthna Bhardwaj retweeted
Nineteen seasons.
Nineteen summers.
Nineteen auctions.
Nineteen fresh squads.
Nineteen times people said, “maybe this year age catches up.”
Nineteen times bowlers made plans.
Nineteen times fans carried hope into another IPL.
And through all of it, one man remained.
Virat Kohli in red and gold.
We have seen entire IPL eras rise and disappear in front of our eyes. Legends changed teams. Captains changed cities. Generations changed. The league itself transformed from fearless cricket into data-driven cricket into power-hitting madness.
But one thing somehow stayed untouched.
A man walking out for RCB with impossible expectations on his shoulders.
And still delivering.
Not for 2 seasons.
Not for 5.
Not for a purple patch.
For nearly TWO DECADES.
People will talk about the numbers.
The thousands of runs.
The hundreds.
The chases.
The consistency.
The records.
And yes, they matter.
But statistics alone cannot explain what Virat Kohli has meant to this league.
Because numbers do not capture loyalty.
Numbers do not capture pressure.
Numbers do not capture what it means to carry the hopes of one franchise for 19 straight years in the loudest cricket tournament on earth.
Twelve different IPL seasons with 400+ runs.
Think about that for a second.
In a format designed for chaos…
in a league designed to expose weakness…
through injuries, form slumps, captaincy pressure, scrutiny, trolling, expectations and changing teammates…
he still found a way to show up.
Again.
And again.
And again.
Tonight was not just another innings.
It was another reminder.
That greatness is not only about peaks.
It is about returning.
Every single season.
Every single time people doubt.
Every single time the game evolves.
Every single time younger stars arrive.
And still being the standard.
There are players with bigger power.
Players with crazier strike rates.
Players with shorter bursts of brilliance.
But there has never been another Virat Kohli.
Because nobody has blended hunger, skill, fitness, passion, loyalty, pressure and longevity quite like this man.
For RCB fans, he is not just a player anymore.
He is memory.
He is childhood for one generation.
Adulthood for another.
And inspiration for the next.
Someday the IPL will continue without him.
RCB will continue without him.
New stars will come.
New heroes will rise.
But there will always be a silence when fans realize they once lived in an era where Virat Kohli opened the batting for RCB every summer.
And made it feel normal.
Love you @imVkohli to the moon and back.
Oh.
US nonprofit hospitals spent $7.8 billion on management consultants from 2009 to 2023, but contracts were not associated with meaningful changes in finance, operations, or quality of care. 🧵
ja.ma/4d46zfq
Prarthna Bhardwaj retweeted
Leadership should not be mediocrity dressed up in titles.
Leadership is vision, excellence, and the ability to inspire.
Titles sometimes go to people who are compliant to those who appoint them than to those who are excellent and will challenge authority when needed. But we must always seek excellence in leadership.
The world may continue without you in many places. But in a few, irreplaceable corners, it simply doesn’t know how to.
A profound reminder of what’s most important in life!
"Medicine can have extraordinary meaning. But it cannot substitute for being present in your own life."
In #APieceofMyMind, a psychiatrist and residency program director reflects on an unexpected #LungCancer diagnosis.
ja.ma/48OxHxC
It’s @TumorBoardTues time again! Join @YAbdouMD and myself in a few mins to learn more about oral SERDs
#TumorBoardTuesday
Good morning @TumorBoardTues crowd - looking forward to diving back into the learning, as we exit winter🌨️
📢Join us Tuesday, 3-3-26 at 8PM ET as @YAbdouMD & @prarthnavb 🗣️the use of oral SERDs in HR+ metastatic #breastcancer
RT and bring others into the discussion‼️
Prarthna Bhardwaj retweeted
#TumorBoardTuesday
Good morning @TumorBoardTues crowd - looking forward to diving back into the learning, as we exit winter🌨️
📢Join us Tuesday, 3-3-26 at 8PM ET as @YAbdouMD & @prarthnavb 🗣️the use of oral SERDs in HR+ metastatic #breastcancer
RT and bring others into the discussion‼️
Prarthna Bhardwaj retweeted
I’m really happy to say this out loud: I finally found a place where I am trusted to lead.
Not just a title. Not responsibility without authority. Real trust. Real support. Real sponsorship. Today a piece I wrote for Forbes went live, inspired by so many stories from women in healthcare. Talent isn’t leaving because women aren’t strong enough. It leaves when the emotional tax becomes unsustainable and leadership falls short.
Being in a place where “we trust you” is actually lived out feels almost radical. It brings back your voice, your confidence, your joy in the work. When women are trusted to lead, everyone wins. Grateful today. Hopeful always. Paying it forward.
@forbes forbes.com/councils/forbesbu…
Prarthna Bhardwaj retweeted
Confused by the explosion of new ER-targeting agents at #SABCS25? 🤯
It is no longer just "SERDs." The vocabulary of HR+ Breast Cancer is evolving.
We now have PROTACs, CERANs, and next-gen SERMs.
Here is the mechanism cheat sheet you need 📝:
🔹 SERD (Degrader):
Mechanism: Destroys the ER.
Drugs: Elacestrant, Giredestrant, Imlunestrant, Camizestrant.
🔹 PROTAC (Chimera):
Mechanism: Hijacks the ubiquitin system to degrade ER.
Drug: Vepdegestrant.
🔹 CERAN (Complete Antagonist):
Mechanism: Fully blocks ER (degradation independent).
Drug: Palazestrant.
🔹 Novel SERM (Modulator):
Mechanism: Tissue-selective modulation (brain-penetrant).
Drug: Lasofoxifene.
Different mechanisms = different resistance profiles. 🧬
Bookmark this slide for the boards (and the clinic). ⬇️
@OncoAlert #bcsm #Oncology #MedEd
4 Major Takeaways for clinics :
#SABCS25
1️⃣ Monotherapy is out: "Era of endocrine monotherapy for ER+ mBC is over" (with rare exceptions).
2️⃣ Profile Early: You cannot treat 2L correctly without genomic baseline.
3️⃣ Resistance: We are still learning if "SERD after SERD" works.
4️⃣ New Std of Care: ET partner + Targeted agent is the goal.
@OncoAlert
Prarthna Bhardwaj retweeted
Multimodal AI has arrived in breast ca! An avalanche of compelling presentations at #SABCS25
-multimodal ICM+ w/pathomics is prognostic and provides better performance for late recurrence than ODx in TAILORx
-check out Rapid Fire 3 for more on TAILORx, NSABP B-20, NSABP B-42
Finally caught up on the brilliant, inspiring talk by @AGiulianoMD. Change is hard. We are wired to resist it. In medicine, change is not just progress; it is correction. Takes humility to rewrite what we thought we knew and the courage to act even when it challenges tradition!
Brilliant discussion by @DrLisaCarey on lidERA and future directions #SABCS25
Do we have a new SOC for adjuvant ET in HR+HER2- eBC?
Yes for :
📍 high-risk disease
📍 similar side effects and fewer discontinuation compared to AI/tam
📍 Esp those receiving chemo
However:
💲cost?
Stage 1 cancer?
#SABCS25
Prarthna Bhardwaj retweeted
While negative studies are not always as flashy or exciting, they are critical to answer important questions and guide further evidence-based and guideline concordant care for our patients! #SABCS25
Prarthna Bhardwaj retweeted
ASCENT-07 presented by @jhaveri_komal: in ET-refractory ER+/HER2- MBC, in a mostly visceral met population, first-line SG did not improve PFS vs. chemo. Best PFS observed with capecitabine, which, along with T-DXd, remains the preferred option to consider in this population.
Prarthna Bhardwaj retweeted
@IlanaSchlam beautifully presenting 6 month follow up from TRADE adjuvant abemaciclib study, confirming benefit of early dose escalation improving drug tolerability. @DFCI_BreastOnc #SABCS25

































