@pollinalab

Assistant Professor of Developmental Biology @WUSTLmed Nervous System Longevity and Rejuvenation, neuronal activity, epigenetics, DNA damage, Sleep

 St. Louis Missouri
pollinalab.com/
Joined September 2022
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  • Following224
  • Followers417
3Media
Indeed, clearly supporting the idea that NuA4/TIP60 does not use the same molecular mechanism as SRCAP to engage nucleosomes in order to incorporate H2A.Z. The multiplicity of histone mark reader modules in NuA4 likely playing a role.
The Nogales Lab@NogalesLab1 Aug 2024
Replying to @NogalesLab
Please also take a look at related work by @rklouder and Carl Wu at @HopkinsMedicine diving into different functional states of the human SRCAP remodeler and a comparison with TIP60. Recently out in @biorxivpreprint biorxiv.org/content/10.1101/…
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Another brave student joins the Pollina lab. Welcome Joowon!
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Our first qualified PhD student- Congrats to @ena_haseljic for passing her QE. Excited to see what she discovers!
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Elizabeth Pollina retweeted
Xin Gu@XinGu031724 Aug 2023
Over the moon about my postdoc work ⁦@ScienceMagazine⁩ ! Ever wonder about how mammalian cells selectively degrade unwanted nuclear proteins without involving ubiquitination? Check out our paper on a non-canonical protein degradation mechanism! science.org/doi/10.1126/scie…

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Midnolin associates with the proteasome to promote degradation of nuclear proteins through a ubiquitination-independent mechanism.

science.org
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Thrilled to welcome @ena_haseljic as the first grad student in the lab! @WUSTLdbbs @WashUDevBio
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Happy to see the preprint of the work I collaborated with during my postdoc at @EricGreerLab finally out! 🙌🏻 NOP16, a histone mimic protein that regulates H3K27me3 in breast cancer. biorxiv.org/content/10.1101/…

NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

Post-translational modifications of histone tails alter chromatin accessibility to regulate gene expression. Some viruses exploit the importance of histone modifications by expressing histone mimetic...

biorxiv.org
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Elizabeth Pollina retweeted
Sulagna Das@angalus_d26 Apr 2023
Thrilled to share that our paper is finally online @NeuroCellPress ! We address a paradox - how a short-lived #mRNA , Arc, can maintain long-lasting protein levels to execute its functions for #memory! A short thread... authors.elsevier.com/c/1gzrY…
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Elizabeth Pollina retweeted
Lucas Cheadle@LucasCheadle9 May 2023
Incredibly excited to share that I will be joining the #HHMINEWS family as a Freeman Hrabowski Scholar. This award will fund our work on neuroimmunological mechanisms of brain development and function over the next 5 - 10 years.
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Elizabeth Pollina retweeted
Eugenio F. Fornasiero@euforna2 May 2023
Are you interested in cell lineage tracing in a rapidly aging vertebrate? If so, you might want to check out a cool new preprint from @ItamarHarel lab: biorxiv.org/content/10.1101/…
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Congratulations to @MEGNeuro, as well as @erin_schuman and Christine Holt, for this amazing acccomplishment! We are all so happy and proud!
The Brain Prize
@BrainPrize23 Mar 2023
Congratulations to The Brain Prize winners of 2023: Professors Michael Greenberg, Christine Holt and @erin_schuman. They have done pioneering work on molecular mechanisms of brain development and plasticity Read: lundbeckfonden.com/en/pionee… #TheBrainPrize #BrainPrize23 #neuroscience
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