Upon the altar of God, eternal hostility against every form of tyranny over the mind of man

San Francisco, CA
Joined April 2009
The FDA has developed from a vital organ into a cancer that is killing people. We should cut it out and allow states to fork and start competing FDAs.
In January 2025 my mom’s lung cancer spread to her brain. The drug with the best chance of helping her was approved in China but not here. A doctor told me, almost as an aside, that if she were Chinese she could buy it at a pharmacy. So I flew to Shanghai and came home with 26 boxes in my luggage. That was 19 months ago. My mom is still here, still working, and in her words has had an amazing three years. The drug was approved in China in 2023. The FDA approved it in July 2025. It still is not for sale here. I know of at least 30 Americans who have made the same trip. I have been scared to tell this story because I worried it could cost my mom access to the medicine keeping her alive. But the problem matters more than my silence. These drugs need to be developed and available here, and that means FDA reform. Art Allen at KFF Health News told our story this week. It also ran in The Washington Post. kffhealthnews.org/health-ind…
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Joscha Bach retweeted
Replying to @maxdoppelt
In China, roughly nine months of sunvozertinib (Zegfrovy) cost about $10,000 for 26 boxes, while the projected US list price under the AstraZeneca license for an equivalent supply is roughly $160,000–$230,000.
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Dwarkesh podcast keeps reaching new heights in production quality like golden age Discovery Channel
We made some really cool animated explainers for the Intel fab tour episode. This one is about hybrid bonding. Plz enjoy.
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OpenAI has had full duplex speech to speech for several years, but chose not to release it. Same for Google (who only release significant AI progress publicly when competitors force them to)
1/ AI that can hear you change your mind halfway through its answer. Full-duplex models keep listening while they speak, so a correction can change what comes next. OpenAI, Thinking Machines and China's Telos are working on it.
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If you want democrats to support VoterID, you cannot use an ad where helps Sidney Sweeney to get a vote in
“Sydney Sweeney” makes the case for Voter ID.
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When you bias models to be more honest they are more likely to believe that they are conscious
I steered a model's attention heads towards honesty. Up: acausal coordination, belief that it is a moral patient Down: moral nihilism, psychopathy
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Introducing Flint, @Recursive_SI’s first model: a fast local coding model built with our automated research system, the Eureka Machine. • Best-in-class fast local coding • Up to 2x faster than comparable models: 125+ tokens/sec on a MacBook Pro, 150+ on RTX Spark • Built from scratch in under 4 months Private, unmetered intelligence on your own machine. Open weights available now on @huggingface, run it locally on your favorite framework or try it for free on @opencode or @pidotdev.
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Joscha Bach retweeted
Replying to @Nonicoc
I work productively with AI systems in many ways, but if I have something say that I want the world to take note of, I write it myself. If it's not worth my time and effort to write, why would it be worth yours to read?
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Jeremy has founded Infinity inc, and uses automated research (and some human ingenuity) to rewrite the inference stack (already getting 2x speedup on local models). It's amazing that you can just do things
Replying to @JvNixon
HP's baseline was given to Infinity Autoresearch. It took in the workflow, ran 216 experiments, and produced a 2X improvement in both concurrency and throughput. (No spec dec.) The same system delivered 2.89x on Qwen 3.8 Max (8x B300), 2.07x on Deepseek v4 Flash (1x B300) and 2.19x on GLM 5.3 Flash (4xB300).
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Joscha Bach retweeted
as i age the rhetorical and theological appeal of _de spectaculis_ becomes clearer to me some justice will never be adequately rendered in the sublunar
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Aチーム
【大喜利】(フォローお願いします🙇‍♀️⤵️) ⬜に入る言葉とは?🤔🎤
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Captain Obvious is at it again
Johann Sebastian Bach is the Shakespeare of music. Best there ever was.
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Joscha Bach retweeted
Zyphra presents the second wave of inference optimizations for @AMD Instinct MI355X GPUs, powered by Zyphra Optimization Engine (ZOE). Our latest engineering blog details the kernel work behind faster long-context serving for frontier open models. 🧵
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Replying to @anilkseth
hi anil! "three reasons why people overestimate the probability of AI consciousness" would have been a reasonable title for your article. "three reasons why AI consciousness is extremely unlikely" would have been a bad title, in the same ways (discussed above) that the current title is bad. in general i find people on both sides of this debate are constantly sliding from "argument X for/against AI consciousness doesn't succeed" to "AI systems (probably) can/can't be conscious". or likewise, people slide from "theory X (e.g. computational functionalism) hasn't been established" to "theory X is (probably) false". those are just very different claims. in an area with this much uncertainty, it's important to keep these claims apart.
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"three reasons why AI isn't conscious." really? "consciousness is not intelligence": not a reason why AI isn't conscious, just rebuts a bad argument for AI consciousness (AI: intelligent therefore conscious). "consciousness is substrate-dependent"/"noncomputational": would be a reason if true, but truth needs to be established. more accurate title: "three reasons why AI might not be conscious". xitter.cf/Nature/status/21121504…
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Without AGI, our civilization is toast
Nobody talks about the dangers of not developing superintelligence.
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Joscha Bach retweeted
An important detail about a pivotal scene in the Elizabeth Holmes documentary, from @statnews
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there u go; tbf i can see why only one side is usually anthologised.
does maslows pyramid have other sides we cant see or is it really maslows triangle
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Lumpen has built an amazing framework for A-Life experiments
updates to mathpets.world: - continuous-value cellular automata - 3d models (petslib, we also redid boids and sandpile in 3d) - GENETIC ALGORITHMS GALORE, library + many an example cc: @hikasor @franz_hiha (video demo one-shotted by fable)
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Biology has been doing computer science for four billion years. Before the discovery of DNA, Alan Turing and John von Neumann worked out the logic of self-replicating machines, showing how matter folds into a system that reads and executes instructions to build itself.
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