🇦🇷🇨🇭 we are yesterday's answers

Zürich
Joined April 2009
Is BBC a fraud?
Israel-bound flight diverted after fight between pilots bbc.in/4z6SCqA
Readers added context they thought people might want to know
The copilot stabbed the pilot in an attempt to hijack the plane until passengers stormed the cockpit and subdued him. The plane plummeted over 17000 feet during the attack and other pilots who were passengers on the plane took control and landed it. cnn.com/2026/09/30/wor… jpost.com/international/… msn.com/en-us/news/oth…
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Today we announced the Claude-led discovery of a molecular machine that we suspect could represent a new gene editing mechanism. Its precise function, biotechnological utility (if any), or level of significance is not yet clear, but at minimum it is work I would have been proud to do as a PhD student. The work was done mostly, though not entirely, by Claude: our life sciences team suggested a broad area of research, Claude read through the literature and a bunch of genome data and discovered something interesting, then Claude proposed experiments to verify the discovery and our team carried them out. It’s easy to dismiss this as a one-off or curiosity, but we’ve repeatedly seen a pattern where AI performance in new intellectual domains goes from weak to superhuman in a matter of a few years. In 2023 models struggled to do math at the level of an average high-school student. In 2024 they started to do well on math competitions for the best high-schoolers in the country, in 2025 they started to solve minor open problems, in early 2026 more significant open problems, and in late 2026 they are beginning to solve the top few open problems in all of mathematics. We believe AI for biology is on a similar exponential trend. The main difference between biology and mathematics, of course, is that math can be done purely theoretically, while biology requires experimentation. Some have used this to draw the conclusion that AI’s utility in biology will be limited. We think this is wrong. As we’ve demonstrated today, humans can collaborate with AI to perform the experiments, validate key results in a few weeks and, if necessary, work with the AI to iterate on what they find. Eventually it may even be possible for Claude itself to safely perform the experiments by autonomously controlling lab equipment, with appropriate safeguards in place, but we aren’t doing that today (our lab is also a BSL1/BSL2 facility that doesn't handle materials dangerous to humans). More broadly, biomedical advancement has many stages — from fundamental biology discoveries, to translational research, to drug discovery, clinical trials, and finally the actual delivery of medicines and health care to patients. We are also interested in these later stages, but even simply accelerating the first stage of fundamental biological discoveries has the potential to speed up and broaden the entire pipeline. Improving our understanding of biology and sharpening biologists’ tools can drive forward all of the later stages, for example by identifying new drug targets, finding new therapeutic modalities, allowing for more precise measurement, and speeding up the experimental loop which itself further accelerates our understanding of biology. This will not in itself speed up clinical trial times, but if it succeeds it could greatly increase the number of promising candidates that go into the pipeline — an increase in throughput even though latency remains. In Machines of Loving Grace, I wrote about AI’s potential to “cure most diseases in 5-10 years” — a goal that sounds impossible, but one I believe is just barely possible if AI is applied to every stage of the pipeline. The first step is showing that AI can first help with, and then drive, biological discoveries. Claude’s discovery is the latest in a line of related prior work that goes back decades, beginning with systems like CRISPR, and continuing with discoveries like the bridge recombinase and VIPR in the past few years. Recently, there has been heightened interest in systems based on reverse transcriptase (RT) enzymes, the enzyme underlying the system Claude identified. And most recently, a Stanford team working independently described a novel RT system with an associated non-coding array that is in some ways similar to the one Claude found, though they are distinct systems that evolved independently from each other. I believe that we’re at the very beginning of finding such systems and developing them into powerful tools for biotechnology. I’m proud of the resources Anthropic has invested in accelerating the public benefits of AI through the life sciences, and we’re aiming both to grow our life sciences team and to work with other scientists to extend this approach to a broad range of problems. If you have a proposal for a research collaboration or are interested in joining our life sciences team, please reach out.
Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR. We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use. Read more: anthropic.com/news/claude-di…
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Amazing new world
"Superintelligence is within reach." If this is true, you could have just years to enjoy the world as it currently exists. Soak it in. Do that thing you've always wanted to do. How much did the trench-dwelling soldier of WW1 wish he could relive the halcyon days of pre-war Europe? Do future you a favor and eliminate the biggest regrets you may have. For the first time, humans could become the second most intelligent species on the planet. Creating a superintelligence means handing over our control to something far smarter than ourselves. Just as every other species is here by our good graces... So too will we survive if and only if the superintelligence deems it appropriate. That may sound absurd. But there's nothing that physically prevents it. It's possible, and some even say likely by 2030. And when it arrives, our entire economic system is obsolete. Since it's coming either way (every great power is in a race to make it happen) let's focus on the most optimistic outcome: Billions of brilliant virtual workers will solve the most critical engineering problems we face. They will invent new materials and unlock abundant energy. They will create software that enables general-purpose robots. They'll invent flawless self-driving vehicles to transport materials. Or maybe they will synthesize materials where they're needed instead of transporting them? Robots will eventually self-replicate to create a workforce of billions that are willing to work around the clock at the equivalent of $1 dollar an hour. They will rapidly rewire our electrical grid to support their aims. Or perhaps invent a new form of wireless, distributed energy. With mental work done far cheaper and more brilliantly than any white collar worker, and with billions of cheap laborers doing the physical work... Humans labor as a means of survival will suddenly seem barbaric. Your grandchildren will view human labor the same way we view child labor or slavery. This terrifies many people. "People need work to be happy!" And that's partially true. Many a wealthy person, lottery winner, and retiree has faced an existential crisis after they no longer had to work. But consider children. They find joy just by playing with their friends, staring at clouds, running around, and spending time with family. It isn't until they enter the school system that they begin to base their happiness on climbing a ladder, seeking external praise via grades, and focusing on their relative standing amongst their peers. In other words, we have all been conditioned to seek happiness in the external. But that's merely a byproduct of a world of scarcity where human competition determines access to resources. It's a matter of mindset and personal philosophy. With basic needs covered, the biggest challenge most humans will face will be how to survive the transition without falling into despair and depression. Someone who was conditioned to value themselves based on their work may feel "useless" - but someone who values themselves based on how good of a friend, father, lover, they are could thrive. In terms of investing and business... How will businesses compete with a superintelligence? How will a business maintain profits if everyone has access to nearly unlimited intelligence, labor, etc.? If anyone can tell the magic genie: "make me an e-commerce brand that provides me $10 million per year in post-tax income" And then have a virtual army of workers outperform even the most skilled human entrepreneurs to make that happen... What business has a durable moat in that world? Any profit will be immediately targeted and competed away. Investing in equities becomes a very difficult proposition. Almost everything will be abundant, but there will still be desirable things that are scarce: - Your own time - Waterfront real estate - Access to pristine nature - Bottles of La Tâche Grand cru And finite #Bitcoin To the extent that we still need to store value to determine who has access to those scarce things, the most logical idea is to store it in the scarcest, most predictable monetary asset possible. And for now that is undeniably Bitcoin. Nearly everything else will be increasingly abundant compared to finite Bitcoin. But how will people get Bitcoin? There will still be things that only humans can do. Human touch, in-person conversation, experiences, sports, human entertainment like standup comedy, etc. "Hand made" products could also maintain an appeal for a while because of their relative scarcity and wabi-sabi compared to mass-produced items. The people who still desire rare luxuries, such as a bottle of DRC, will have opportunities to earn Bitcoin. We are already in the early stages of this world. Technology has already given us a level of abundance and wealth that people 100 years ago would have dreamed of. The fiat world is designed to transfer these gains to the money-printing class... But those who have already adopted #Bitcoin as their savings technology have watched their purchasing power and control over their time increase. Anyone can opt into this superior system at anytime. Bitcoin gives you more time. It makes every desirable good more affordable. It makes basics like food seem abundant. In other words, Bitcoin lets you live in the future, today.
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The price of freedom. Not bad
Free speech wasn’t free. I paid $44,000,000,000.00 for it.
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Para salir de la Echo chamber
Un consejo que me cambió X: dejá de mirar el feed "Para ti". Miralo por tópicos. El mío favorito es ciencia, después tecnología y business. Se hace en dos segundos: tocás el "+" arriba de la pantalla y agregás los temas que te interesan. De golpe X deja de ser una máquina de bronca. No más política, no más peleas, no más cosas puestas ahí solo para que te enfurezcas. Empezás a ver gente que descubre, construye y crea. El feed "Para ti" vive de tu enojo, porque el enojo engancha y te retiene. Los tópicos viven de tu curiosidad. Elegí curiosidad.
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Siempre la ve clara
Cuiden Ceuta, Melilla y la costa.
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Antisemitas y pro terrorismo me denunciaron masivamente la cuenta y la tengo shadowbaneada (invisibilizada). Ayúdenme con RT y sugiriendo que me sigan, para romper esas restricciones. Gracias a todos !!!
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J.K. Rowling: “It’s impossible to live without failing at something, unless you live so cautiously you might as well not have lived at all, in which case you failed by default”
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peter retweeted
Ya está lista la carpeta con más de 200 fotos en HD de la hazaña histórica de hoy; Una fiesta el baile descomunal que le pegamos a Inglaterra. Inolvidable. Una foto mejor que la otra. y NOVEDAD: hay carpeta con videos. PARA COLECCIONAR Dale RT así seguimos con la cábala (están las carpetas de todos los partidos) Lo bajan acá: forms.gle/qeJ7eSyFa3UfobQx6
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So long
Remembering David Hockney, he was kind and always had a sparkle in his eye. He never stopped experimenting and is one of the finest painters of our generation.
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Remembering David Hockney, he was kind and always had a sparkle in his eye. He never stopped experimenting and is one of the finest painters of our generation.
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There are not bad Math students: only bad teachers
People don't hate math; they hate the feeling of being lost. They hate the compounded debt of unlearned prerequisites.
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Just the same that happens with most mass media
“Barack Obama's political genius is his ability to say things that will sound good to people who have not followed the issues in any detail — regardless of how obviously fraudulent what he says may be to those who have.” — Thomas Sowell
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People don’t (want to) see correlation
2021: The Triumph of Big Government 2025: The Coming Debt Emergency. What a surprise... You pay. Sigh.
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Hay que sentarse a discutir cómo levantar las villas. Buenos Aires nunca va a ser Primer Mundo si está llena de villas: La 31 La 1-11-14 La 15 La 20 La 21-24 La Cildáñez Rodrigo Bueno Fraga La carbonilla …
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Con la aplastante victoria de @JMilei quedó en evidencia la complicidad periodística con lo peor de #Argentina. Operaron durante semanas para bajar a #LLA y crearon una realidad alternativa donde aseguraban que el gobierno perdía.
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“If you don't actively shape the story, people just fill in the blanks”
This Redditor dropped a cold reality about PM
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peter retweeted
The purest reason to make something is not to make money and not even to make the thing. It’s to have the experience of making the thing - and no one can take that from you.
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Want to master these 4 patterns and never be exit liquidity again? I've recorded a 17-minute deep dive walking through this system. RT this and comment "PATTERN" and I'll DM you the link.
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Cine en Bologna
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