Médico Nefrólogo

Lima, Peru
Joined May 2009
¿Los inhibidores de bomba de protones (IBP) realmente causan daño renal? Abro hilo 🧵 x/10
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Pablo Angeles Tacchino retweeted
Holy shit an RCT of dialysis access
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En nefropatía por IgA y proteinuria, atacicept, sibeprenlibam y telitacicept, al compararse con comparado a placebo; evitaron la ↓TFGe , logrando alcanzar la reducción fisiológica de TFGe En los ensayos clínicos ORIGIN, VISIONARY y TELIGAN Impresionantes resultados que hacen pensar en la remisión completa y sostenida de esta patología
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Replying to @ASNKidney
@ASNKidney President’s Award goes to Will Flanary. “Cardiology never gave me an award” . Well deserved. #KidneyWk
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During his Presidents Award speach, @DGlaucomflecken talks about his experience and more importantly his wife's experience following his cardiac arrest. Advising people to show compassion to the co-survivors, the family.
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#KidneyWk VISIONARY IgAN Phase 3 (sibeprenlimab update) with @DanaRizk1 24 mo outcomes and safety- eGFR: +1.3 vs -7.9 (placebo) Composite kidney outcome: 1 /259 bs 28/251 (placebo) No patients in sibe group had dbl SCr or needed dialysis AE primarily URI Simultaneous in @NEJM
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Joel was one of my first twitter follows when I started Glaucomflecken 10 years ago. I’ve learned so much from him, like how to say osmolality. Still working out what exactly it is, but at least I can pronounce it.
During his Presidents Award speach, @DGlaucomflecken talks about his experience and more importantly his wife's experience following his cardiac arrest. Advising people to show compassion to the co-survivors, the family.
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More on previously published interim analysis of TELIGAN trial by #nephjc @DrAkshayaJ nephjc.com/news/2026/short/t…
Next up phase three trial on teliracicept, a BAFF APRIL inhibitor. The Teligan trial weekly sq injection, after 39 weeks went to every other week.
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VISIONARY phase 3 data on sibeprenlimab in IgA nephropathy Annualized eGFR slope was +0.3 vs. -4.2 mL/min/1.73m²/yr with placebo, a 4.5 mL/min/yr difference. #ASN #kidneyWk @lsuhs @lsuhs_IM
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Replying to @IgAN_JBarratt
@IgAN_JBarratt presenting the final results of ORIGIN trial #KidneyWk Atacicept in IgAN #NephJC reminder of previously published results: nephjc.com/news/atacicept-or…
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#CD19 CAR therapy holds promise for refractory autoimmune ds @LSUHS_IM @LSUHS
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Next to LBCT #kidneywk @DanaRizk1 on VISIONARY trial 24 months results See #NephJC write up on previously published results nephjc.com/news/2025/11/8/ki…
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We needed the #Nephjc people back on Twitter #KidneyWk fomo.
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What a moment at #KidneyWk @DGlaucomflecken receiving this years President's Medal And he gives a huge shout out to @kidney_boy @NephJC #Homeostasis And yes Morton Salt has appeared. Kudos to @ASNKidney
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and the conclusion #KidneyWk
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4/ ⚠️Not all congestion is the same! #KidneyWk 📍LV diastolic dysfunction: ⬆️ filling pressures can cause pulmonary congestion 🦠Sepsis: vasodilation can lower blood pressure even when filling pressures are elevated 🫀Right heart failure: systemic venous congestion may occur without pulmonary congestion
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2/Can the jugular vein help estimate right atrial pressure (RAP)? #KidneyWk 👉IJV height: Find where the vein collapses (the wine bottle sign). Its vertical height helps estimate RAP 👉IJV collapsibility: Assess how the vein changes with breathing 👉Valsalva maneuver: A smaller increase in IJV cross-sectional area may suggest elevated RAP
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5/ When is an AV fistula mature? #KidneyWk ⚠️The traditional rule of 6s (>6 mm diameter, <6 mm depth, >600 mL/min flow) is being challenged ⚠️The slide proposes lower thresholds: 5 mm diameter and >500 mL/min flow
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Los IBP (ej. omeprazol) se asociaron a ↑2.5 veces el riesgo de desarrollar hiponatremia severa (Na <125 mEq/L), sobre todo en las primeras 3 semanas del inicio Hipótesis: induce SIHAD y/o hipomagnesemia que influye en la bomba Na/K ATPasa Kidney360 2026 10.34067/KID.0000001412
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✅ Renal POCUS: SECONDS checklist #KidneyWk @JaberiAala @NephroP ✅A systematic approach to kidney ultrasound: ☑️S – Size: Assess kidney length and cortical thickness. ☑️E – Echogenicity: Compare renal cortex with the liver or spleen ☑️C – Collecting system: Look for hydronephrosis and urinary tract dilation ☑️O – Outline: Check renal contours for irregularities or masses ☑️N – Notable lesions: Identify cysts, stones, or focal abnormalities ☑️D – Doppler: Assess renal perfusion and vascular abnormalities ☑️S – Surroundings: Look for perinephric collections or other adjacent abnormalities
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🩵📧 Kidney Week moves fast... let us keep you in the loop! Subscribe to the #NephJC newsletter for event updates, highlights, and all the nephrology fun headed your way during #KidneyWk nephjc.com/newsletter
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