A multi-donor fund by Renaissance Philanthropy dedicated to sustaining and evolving the open source software stack that underpins science.

San Francisco, CA
Joined April 2026
Open Source for Science Fund retweeted
🚀 Excited to announce that we are teaming up with @os4science to fund the software stack behind open source science! 🚀 Open science models do not run without open source software, but they rarely get the funding or credit they deserve. We're trying to change that 🤗🤗🤗
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Our inaugural call, Open Source for the Life Sciences, drew hundreds of proposals spanning a wide range of biology disciplines and computational approaches. If you use agents or AI models as a scientist, open source software is what makes it possible.
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The Open Source for Science Fund exists to sustain and evolve the software stack that makes AI-driven scientific discovery possible, and to foster the communities behind it. Want to learn more about our work? Get in touch and join our mission.
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Thank you to the hundreds of teams who submitted letters of intent to our inaugural Open Source for the Life Sciences call. We are energized and inspired by this response. Notifications and invitations to submit full applications are now out. 1/2
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If your proposal wasn't selected to advance, we hope to consider it for future funding opportunities. Want to stay informed about fund updates and new calls? Subscribe to our newsletter: os4science.org/newsletter 2/2
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Missed our info sessions this week? A recording is now available! • Video: drive.google.com/file/d/1wcd… • Slides: docs.google.com/presentation… Still have questions? Check out our FAQ page or reach out directly at [email protected] The Letter of Intent deadline is June 8th.
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A reminder that our webinars are this week. Sign up if you want to learn more about the current call for proposals and ask us anything:
📣 The inaugural Open Source for the Life Sciences funding opportunity is live! We're hosting two information sessions to help you learn more, ask questions, and understand the application process. Sessions cover the same content, register for whichever time is most convenient:
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A new open source project from our sister program, the Mathlib Initiative, at Renaissance Philanthropy. Check it out:
Launching today: Formal Frontier from the Mathlib Initiative, a program of @RenPhilanthropy and funded by @xtxmarkets. Formal Frontier will focus on responsible, scalable, and open-source AI-driven autoformalization of mathematics. Read more and learn how to get involved: mathlib-initiative.org/forma…
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📣 The inaugural Open Source for the Life Sciences funding opportunity is live! We're hosting two information sessions to help you learn more, ask questions, and understand the application process. Sessions cover the same content, register for whichever time is most convenient:
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🗓 Session 1: Wednesday, May 27 (&28) [6:00 pm PT | 9:00 pm ET | 1:00 am UTC (May 28)] zoom.us/webinar/register/WN_… 🗓 Session 2: Friday, May 29 [7:00 am PT | 10:00 am ET | 2:00 pm UTC | 4:00 pm CEST] zoom.us/webinar/register/WN_…
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How does the fund work? How can you join as a funding partner? How to apply for funding? We've got you covered, check out our FAQs: os4science.org/faq/
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Open Source for Science Fund retweeted
Exciting new funding opportunity for open source software in the life sciences: @os4science has launched its inaugural call for proposals. Definitely worth a look if you’re building in this space!
📣 New funding opportunity. Today, we're launching our inaugural call for proposals for open source software that underpins data-intensive research and AI-driven discovery in the life sciences. 1/ os4science.org/funding_oppor…
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📣 New funding opportunity. Today, we're launching our inaugural call for proposals for open source software that underpins data-intensive research and AI-driven discovery in the life sciences. 1/ os4science.org/funding_oppor…
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Two application tracks: Track 1. domain-specific software tools across a broad range of disciplines in the life sciences (up $250,000) Track 2. foundational libraries as well as collaborations among related projects within the same software ecosystem (up to $1,000,000) 3/
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Across these two categories, we will give priority to applications that enable large-scale data analysis and AI-driven applications and workflows. Letters of intent (LOI) are due June 8, 2026. Full application details at: os4science.org 4/4
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