Neurologist
London, UK
Joined June 2009
- Tweets174
- Following925
- Followers422
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Happy to share I’ve have been awarded a fellowship by NIHR to develop safe useful clinical conversational AI in the NHS @ImperialBrains @UKDRI
We’ll start with a focus on TBI & cognitive problems. Find out more here; and do get in touch if you’d like to collaborate or join the lab (PhD opportunities available)
appliedhealthintelligence.su…
Lab webpage - appliedhealthintelligence.io
Get in touch if you’d like to know more!
Finger-prick blood testing🩸shows promise to help traumatic brain injury / Alzheimer's diagnosis, as this remarkable technology continues to improve.
Wonderful working with @NicholasAshton Magda Mike Hanna Henrik @PareshMalhotra @Neurosharp & more on it: academic.oup.com/braincomms/…
Great opportunity to join @Neurosharp team at @ImperialBrains as a research assistant, working on late-consequences of military neurotrauma. Do reach out if you'd like to know more about the role. (Closing date 1st April)
imperial.ac.uk/jobs/search-j…
Neil Graham retweeted
Many thanks to esteemed authors especially @ajlees and of course @TheLancet for helping us write the third in this series of articles on Parkinson’s. authors.elsevier.com/a/1iSC0…
Neil Graham retweeted
We evaluated the biological variation of 🩸 p-tau (217, 231, 181), Aβ, NfL and GFAP weekly over 10 weeks in healthy individuals aged 40-60.
An important read for anyone interested in AD 🩸 biomarkers - there’s much more we need to know beyond AUC’s!
alz-journals.onlinelibrary.w…
Neil Graham retweeted
If you are a retired player between the ages of 30 and 55 and would like to check your eligibility for a brain health assessment, contact @theISEH Advanced BRAIN Health Clinic.
➡️ iseh.co.uk/patients/clinical…
Neil Graham retweeted
This month, PFA CEO @Maheta_Molango and Chair @BecklesOmar visited the Advanced BRAIN Health Clinic at @TheISEH in central London.
The clinic provides confidential, specialist clinical assessment for mid-life retired male and female professional footballers, and uses data to help unlock a greater understanding of sport-caused neurodegeneration.
Learn more: thepfa.com/news/2023/11/15/m…
Semaglutide in nondiabetic adults with obesity - remarkable cardiovascular effects (MI, stroke) with also a significant drop in mortality. Trial in NEJM nejm.org/doi/full/10.1056/NE…
Informative discussion of new Alzheimer’s treatments, with @PareshMalhotra @ProfRobHoward on @BBCMoreOrLess. A great listen.
bbc.co.uk/sounds/play/m001r1…
Neil Graham retweeted
Parker et al. report that head injuries during elite rugby games may result in localised cortical swelling that correlates with astrocytic activation and long-term reductions in cortical thickness. tinyurl.com/4xfb3j5s
Pleased to see this comment with @Neurosharp published looking at the great work of the TRACK TBI team on dynamic patient trajectories years post-injury.
More to be done to understand things at a mechanistic level but key implications for patient monitoring & treatment trials.
New online! Clinical outcomes evolve years after traumatic brain injury dlvr.it/Sw0fB8
Neil Graham retweeted
"Associations Between Traumatic Brain Injury and Cognitive Decline Among Older Veteran Men - A Twin Study"
Twin study data demonstrating lifelong #BrainHealth consequences of #TBI.
n.neurology.org/content/earl…
Important paper on a new fluid biomarker for tau tangle pathology (MTBR-tau243) in Alzheimer's disease. The authors show it works well in CSF. Next step is blood testing. Awesome work. Will be interesting to know if this works in other tauopathies like CTE 👏👏👏
💥 #CSF #MTBR-tau243 is an accurate #biomarker of aggregated #tau and clinical #cognitive impairment in #Alzheimers disease, with higher specificity than current #phospho-tau biomarkers. #AD @OskarHansson9 @gesalbla @biofinder_study @KantaHorie
nature.com/articles/s41591-0…
The team has previously published on the performance of different markers MTBR-tau275 and 282, which do pretty well with CBD, PSP, FTLD-MAPT (and AD to a lesser extent) . Seems like an important new direction. ncbi.nlm.nih.gov/pmc/article…
A superb innovation from the Imperial cardiology team.
Imperial's new Clinical/Academic Cardiology Fellowship
Motto:
"We never forget,
you have a choice"
jobs.nhs.uk/candidate/jobadv…
Open to budding cardiologists, and also to existing cardiology SpRs.
Neil Graham retweeted
Many congratulations to all partners on securing funding for TBI Reporter, an ambitious platform for TBI research @Menon_Cambridge @pja_hutch @WillStewNeuro @Neurosharp
ukri.org/news/research-platf…
Neil Graham retweeted
Why many Aβ-positive cognitively unimpaired individuals do not develop downstream tau pathology? Our new study led by @BellaverBruna published in @NatureMedicine shows that looking at reactive astrocytes may help start solving this question. rb.gy/y9qkj
