@njwalker

CTO at Enhanc3D Genomics. SciPolicy, Bioinformatics, Epigenomes, Julia, KiwiStuff

 Cambridge, England
Joined June 2008
  • Tweets241
  • Following1.2K
  • Followers267
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1/Now published @GenomeBiology! Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet. By @cobyviner @CharlesIshak @njwalker @HS_HuiShi @marcela_sjoberg @roxs88 @David_J_Adams @AnneF_S @decarvalho_lab @HainerLab et al! genomebiology.biomedcentral.…

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

Genome Biology - Transcription factors bind DNA in specific sequence contexts. In addition to distinguishing one nucleobase from another, some transcription factors can distinguish between...

link.springer.com
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Bit of a milestone here. Tuatara genome (~5 GBp) is now up on Ensembl. This is a resource developed in partnership with Ngatiwai iwi, with assistance from a large global team of researchers. Lots of insights emerging and the main paper isn’t too far away now. – at Dunedin City, New Zealand
Ensembl@ensembl10 Jan 2019
The latest release of Ensembl includes 9 new species: #redfox, #koala, #polarbear, #blackbear, #dingo, #donkey, #paintedturtle, #tuatara and #Agassizsdeserttortoise as well as updated #genome assemblies for #cow, #chicken and #horse. Phew! buff.ly/2R9dEo3 #Ensembl95
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Nic Walker retweeted
biomodal@biomodalhq8 Jan 2019
Cambridge Epigenetix is excited to announce its discovery and development programme for routine screening and detection of colorectal cancer and other common cancers using a standard blood draw: bit.ly/2SInJFg
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This is great. And should always be included. But... it really drills home the common approach nowadays: “lets try 100 random structures and pick the only one that improved our metric.”
James Bradbury@jekbradbury29 Sep 2018
A huge fan of putting this in papers (from the BigGAN paper openreview.net/pdf?id=B1xsqj…)
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Super exciting to be able to use @GoogleCloud @GoogleGenomics for our Biomarker Discovery efforts in Bioinformatics. Especially for all the cool stuff that's happening with #machinelearning in @njwalker 's team.
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My command-line bootcamp is used by hundreds of universities and teachers - but it has no funding. My digital ocean account is currently locked. Looking for someone who benefits from it to sponsor by providing a digital ocean droplet for the backend. rik.smith-unna.com/command_l…
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Margaret Brimble: being the first Kiwi woman elected as a fellow of the Royal Society of London is a win for New Zealand and a win for #womeninscience nzherald.co.nz/nz/news/artic…
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Nic Walker retweeted
biomodal@biomodalhq15 Mar 2018
We've launched our HMCP biomarker discovery service offering highly-sensitive & specific detection of #5hmC from a range of sample types & providing valuable information on cell and disease states. Available to select partners as part of an Early Access Program.
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#Epigenetics 2018
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Upcoming free online Julia tutorial next week, December 19! #julialang youtube.com/watch?v=4igzy3bG…
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Parts of #NewZealand with no people living within 1 square kilometer. #dataviz reddit.com/r/MapPorn/comment…
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1969: -what're you doing with that 2KB of RAM? -sending people to the moon 2017: -what're you doing with that 1.5GB of RAM? -running Slack
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Save the date: JuliaCon 2018, Aug 7-11 in London! juliacon.org/2018/
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my daughter is taking an ungrad bioinformatics course. I'm happy to hear she is learning the important stuff
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We need a tag to indicate whether someone's actually looked at - let alone critically read - the paper they’re gleefully (re)tweeting...
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Nic Walker retweeted
Mark Riedl@mark_riedl7 Mar 2017
Google Brain has re-discovered that evolutionary algorithms can optimize neural network architectures. Ramped it up to insane scale. xitter.cf/Miles_Brundage/status/…
Miles Brundage
@Miles_Brundage6 Mar 2017
"Large-Scale Evolution of Image Classifiers," Real et al. at Google Brain/Research: arxiv.org/abs/1703.01041

Large-Scale Evolution of Image Classifiers

Neural networks have proven effective at solving difficult problems but designing their architectures can be challenging, even for image classification problems alone. Our goal is to minimize...

arxiv.org
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An absolute goldmine of bioinformatics lectures from @aaronquinlan, thanks so much for making them public/CC-BY-SA!! github.com/quinlan-lab/appli…
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Our paper on methylation detection using @nanopore sequencing is now out nature.com/nmeth/journal/vao… Thx @timp0 @IdeaAntenna @ljdursi @mateidvd
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Nic Walker retweeted
Winston Timp@timp020 Feb 2017
Our paper on "Detecting DNA cytosine methylation using nanopore sequencing" is out: nature.com/nmeth/journal/vao… 1/2
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You're not studying "DNA methylation", you're studying "DNA methylation patterns", which report many diverse influences #EWAS #epigenetics
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