Studying the cancer-cardiovascular disease interplay, with a focus on how cancer reprograms the hematopoietic and immune systems, at the Francis Crick Institute
London, England
Joined December 2007
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- Following2K
- Followers1.5K
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Jose M. Adrover retweeted
🎉Our paper on #PDAC and #Pancreatitis organoid multistroma #cocultures is on the cover of @NatureCellBio! Congratulations to the whole lab!!
Almost 10 years (🤯) after my postdoc paper in @JExpMed, here we are again!! So poetic!
nature.com/articles/s41556-0…
Interested in cancer-associated thrombosis? We are proposing a PACE postdoctoral fellowship to study it in a joint effort between the Crick and UCL. If this sounds interesting, apply here: A dangerous NETwork: neutrophils and cancer-associated thrombosis crick.ac.uk/careers-study/va…
Jose M. Adrover retweeted
A distinct subset of #neutrophils supports placental invasion by secreting the enzyme MMP-9, which enables maternal-fetal interface formation for successful early #pregnancy.
Learn more in Science #Immunology: scim.ag/4h4Pc1p
Jose M. Adrover retweeted
Mouse and human studies show sustained elevated levels of NETs in healing bone tissue can lead to nonunion, a condition that occurs in up to 15% of fracture patients.
Learn more in @ScienceTM: scim.ag/4xpZa2t
Jose M. Adrover retweeted
Recruiting! We are looking for enthusiastic post docs and scientists to study the interactions between neutrophils, macrophages and microbes at the Francis Crick Institute. Please contact me if interested.
Jose M. Adrover retweeted
Thrilled to share our latest work, out in @SciImmunology! We show that tissues match their #macrophage numbers to #mitochondrial_activity , ensuring efficient #waste_clearance and #tissue_fitness . A tour de force by Laura Pena-Couso, in collab with @andrsHidalgo16 & Pura Muñoz🧵
Jose M. Adrover retweeted
We've long wondered what gives NETs their branched architecture. Working with @SCWestLab, @DArmstrongJames we found that RAD51—a protein involved in DNA repair—promotes NET branching & stability, spatially restricting NETs to control type-2 inflammation.
science.org/doi/10.1126/scie…
Jose M. Adrover retweeted
New paper 🚨 We built a mouse model (CD101-tdTomato) to finally track mature neutrophils. Sharing both the findings and the tool — hope labs working on neutrophil biology find it useful👇
Genetic tool for specific tracking of mature neutrophils
Read more on hLife👇👇👇
doi.org/10.1016/j.hlife.2026…
Jose M. Adrover retweeted
Excited to share our new review in @GenesDev!
Cancer is more than a local disease. we discuss how tumors require whole-body metabolism to create tumor-supportive macroenvironment that shapes progression, metastasis and therapy response 👇🏻
🆕 ADVANCE ONLINE 🆕
REVIEW: Metabolic adaptations of the tumor macroenvironment and their role in cancer progression and survivorship
By Devesh Raizada and Ana Gomes
➡️ ow.ly/Xrt750ZunaW
@lab_gomes @MoffittResearch @MoffittNews
#cancer #metabolism
Jose M. Adrover retweeted
Molecular phenotypes and spatial archetypes: A new framework for cancer-associated fibroblasts dlvr.it/TTdHNl
Jose M. Adrover retweeted
Meeting Alert !
📢 New dates for ReThink Neuroimmunology: May 24–26, 2027, at the Weizmann Institute of Science.
Join our spectacular international speaker lineup for bold science and deep discussions.
Registration is open. Space is limited: conferences.weizmann.ac.il/R…
#RTN2027 #Neuroimmunology
Jose M. Adrover retweeted
What the Immune System Does When You’re Not Sick—and Why It Matters for Aging m.yale.edu/dkfb
Great article by our own @AndrsHidalgo16 !! Be sure to check out the video!
I am deeply moved and grateful to receive the Sue Eccles award from the @MetastasisRS, a community whose work I admire profoundly. But it really belongs to all my mentors; they are the ones that helped me reach this point! So this is to you @megeblad and @AndrsHidalgo16
Jose M. Adrover retweeted
Who knew? The most common white blood cells in our body, #neutrophils, are brewing batches of a protein with an ancient infection-fighting pedigree -- and a powerful genetic link to #schizophrenia:
med.stanford.edu/news/all-ne…
Jose M. Adrover retweeted
Online Now: Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage dlvr.it/TSKHTr
Jose M. Adrover retweeted
Excited to share our latest review in @CircRes ! We discuss current knowledge of extracellular mitochondria forms, mechanisms of release, and pathophysiological relevance. Great work by Laura Pena and Magda Makuch in leading this effort!
ahajournals.org/doi/10.1161/…
#Mitochondria
Jose M. Adrover retweeted
Neutrophil inflammation metrics are associated with the risk of future dementia in large data from NYU Langone Hospitals and the Veterans Health Administration alz-journals.onlinelibrary.w…
Jose M. Adrover retweeted
Myeloid cells infiltrate tumors from early transformation to advanced disease; however, their plasticity complicates therapeutic targeting. Nogales-Pons et al @Casanova_Acebes review emerging technologies that uncover unexpected cellular states & functions
hubs.la/Q046y-Bs0
Jose M. Adrover retweeted
All you wanted to know about space, time, myeloid cells and cancer. All wrapped up in a beautiful review 👇👇👇
Kudos @Casanova_Acebes and team
Our view of new (& old but re-formulated) determinants of myeloid biology in tumors is out at @JExpMed. Amazing work from @nogales_pons
@mariolamuna & #teresaaceña. And fantastic editing process with @Gaia_JExpMed (thanks!). Hope you like it, as much as we do #cancerimmunitylab
Jose M. Adrover retweeted
Our view of new (& old but re-formulated) determinants of myeloid biology in tumors is out at @JExpMed. Amazing work from @nogales_pons
@mariolamuna & #teresaaceña. And fantastic editing process with @Gaia_JExpMed (thanks!). Hope you like it, as much as we do #cancerimmunitylab
Myeloid cells infiltrate tumors from early transformation to advanced disease; however, their plasticity complicates therapeutic targeting. Nogales-Pons et al @Casanova_Acebes review emerging technologies that uncover unexpected cellular states & functions
hubs.la/Q046y-Bs0