Faculty @ImperialLifeSci - gene driver @transm0 - fellow traveller @targetmalaria - EngBio/SynBio proselyte “the machines themselves will be different”

London
Joined April 2009
Replying to @BillGates
@BillGates talking about #genedrive as one of the tools in the pipeline that could help end #malaria in the next 20 years @transm0 @TargetMalaria
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Sweeeet! SpliceCraft is now an official Claude Skill which you can enable anytime as of today. I hope this is of service and I welcome any feedback. Thanks for considering my tools for your labors. I'll be supporting this software for a long long time since I use it daily.
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Crazy amount of work by postdoc @s_verkuijl mining nearly all published #genedrive papers for insights! biorxiv.org/content/10.64898…
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Nikolai Windbichler retweeted
🚨 The clearest, most devastating summary of Brexit’s damage which answers every remaining excuse. Brexit caused a slow economic bleed: •GDP is 6–8% smaller than it would have been by 2025: worse than forecast. •Investment is down 18% compared to similar economies. •Employment and productivity are 4% lower. •The damage accumulated year after year, driven by uncertainty, friction and lost integration. Nearly 1 in 10 CFOs spent 6+ hours a week dealing with Brexit fallout for years. Huge amount of time/money preparing for economic sabotage. 👀The killer finding 👉firms most exposed to the EU: 😩 Were the fastest growing before Brexit 😥 Became the most damaged after Brexit Brexit punished Britain’s most productive, outward-facing businesses, the exact engines of growth. Brexit is a rare modern case study of a rich country which proves deliberately raising barriers and the result is: •Lower growth •Lower productivity •Lower wages •Permanent relative decline ⚠️ A BIG warning for any country flirting with economic nationalism, trade wars, or sovereignty over integration.
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Nikolai Windbichler retweeted
How do we monitor the spread of gene drive mosquitoes at scale? 🦟🧪 Our latest preprint (in @biorxivpreprint) defines the Target Product Profile for a rapid diagnostic test (RDT) to detect gene drive presence and frequency. Read more: doi.org/10.64898/2025.12.16.…
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Nikolai Windbichler retweeted
AUDA-NEPAD participated in the 2025 Gene Drive Research Forum in Accra, joining scientists, regulators, and policy experts to advance responsible gene drive governance and strengthen Africa’s readiness for next-gen biocontrol tools. #Agenda2063 Read more: nepad.org/news/auda-nepad-20… @Wiltshire_CNJ
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Researchers from @transm0 have taken a major step forward in developing gene drive modified mosquitoes in Africa 🦟 🌍 The new research brings gene drive technology closer to reality as a tool for preventing malaria transmission. Read more ⤵️ imperial.ac.uk/news/articles…
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Nikolai Windbichler retweeted
Our latest work with @DipteraAI out now on @biorxiv. We built an open, cheap and accessible mosquito membrane feeder 🦟⚙️. 3D-Feedies have been a game changer in our insectaries. Hope you'll give it a try: biorxiv.org/content/10.1101/…
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A new study by researchers from @transm0 @imperialcollege describes a promising #genedrive for #malaria control combining both suppression and modification approaches. 🔬🧬🦟 📷| @CDCgov ➡️nature.com/articles/s41467-0…
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Great @transm0 teamwork with @s_verkuijl taming the beast and @pselvaraj05 spinning up the model!
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Finally, is anyone actually left on X? 🕵️‍♂️
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New paper/gene drive from the lab! Dropped by NComms on Friday evening on World Malaria Day of all times without a word of warning…. nature.com/articles/s41467-0…
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Gene drives that affect vector longevity and induce bloodmeal-specific mortality are predicted to be highly effective in reducing malaria transmission as we show in our model.
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We need to know much more about the complex fitness effects we observe and how they would translate to the field.
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Nikolai Windbichler retweeted
Thank you all for your responses. To summarize, these are free/open source alternatives for preparation of scientific illustrations: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org
Because of annoying complications with the use of images prepared on BioRender @iamscicomm for publication or presentations, our lab will be exploring open-source alternatives like bioicons.com/ or drawing our own images with Illustrator.
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Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems biorxiv.org/cgi/content/shor… #biorxiv_synbio
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