A twice monthly nephrology journal club that meets on Twitter. Hashtag #NephJC

twittersphere
Joined April 2014
#NephJC runs on community magic ✨ We choose to stay free and independent and give back to our community for 12yrs 🩵 If our blogs, podcasts, or visuals have helped you, your donation keeps us going - and might get you into the coolest #KidneyWk party nephjc.com/news/2026/9/8/nep…
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Nephrology Journal Club retweeted
#Kidneywk Run(s) at Denver 📍Friday October 23rd, 6:30 AM. Meet at the giant blue bear in front of the convention center 📍Saturday October 24th, 6 AM, Meet at the Hyatt Regency @NephJC @runningkidneys @ASNKidney nephjc.com/news/nephrun2026
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Join the coolest kidney party of #KidneyWk! 🩵 Just 6 days to go! Grab your ticket here: nephjc.com/news/2026/9/13/th… 🙏Thank you to everyone who has donated already. Your support keeps #NephJC moving forward
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10/10 Final thoughts: Transplant benefits are certainly not universal and require careful conversations about individualized benefits. Up next- ASN #KidneyWeek26 in Denver, CO. Hope to see you there! Check out NephJC.com, become a donor and for party details.
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6/10 Question 1 #NephJC #NephTwitter So, should we transplant all ESRD cases? It depends. SCD kidneys improved mortality in all studied groups. However, SCD kidneys may not be readily available for all waitlisted patients. Worthy of discussion with older, sicker patients.
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8/10 #NephJC Consensus: In most cases, DDKT can improve survival compared to continued dialysis. Not all donor kidneys are created equal (SCD, ECD, DCD, DBD). Discussion of recipient and donor quality should be undertaken during transplant evaluation, as well of goals of care.
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7/10 Question 2 #NephJC #NephTwitter Should older/sicker patients risk transplant? These are the individualized conversations that are needed. Although older pts receiving poorer kidneys (ECD) didn’t show mortality benefit, QoL is still an important consideration.
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5/10 A picture paints 1000 words As the donor & the recipient “quality” ⬇️, so do benefits. Although higher quality kidneys (SCD) did better in worse recipients (those >75, DM+, CVD+), should they have access to SCD kidneys if overall survival is ⬇️ than younger candidates?
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3/10 1 post methods -SCD, ECD, donor after brain death (DBD), donor after CV death (DCD) -4 transplant groups: SCD/DBD, SCD/DCD, ECD/DBD, ECD/DCD were compared in 4 patient groups: All, DM+, CVD+, neither DM/CVD The 16 trials generated 1,491,537 person-trials
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4/10 1 post results 64.1% ♂️, mean age 55 years; median dialysis vintage-238 days. Comorbidities include DM (26%), CVD (25%). For pts > 75 ECD/DCD kidneys did not show a mortality benefit, however, numbers of pts in this category were small.
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2/10 What was the study? 🎯Target trial emulation: using collected data to mimic a randomized trial 🇪🇺 ERA registry: 2000-2019 ✅Included: >20 years of age, waitlisted for receiving a kidney transplant 🧮60 sequential trial emulations
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1/10 #NephJC #TenPostNephJC. #NephTwitter Patient outcomes are better with transplant vs dialysis. Is this always true? What about high-risk donors (expanded criteria donor-ECD) or recipients (elderly with DM or CVD)? Read the article 👇 link to article on pubmed.ncbi.nlm.nih.gov/4275…
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Check out the VA by @danyrcal Do older, sicker patients benefit from kidney transplantation? This is a nuanced "it depends" answer that is worthy of discussion. #NephTwitter nephjc.com/news/targetva
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🚨This week we are looking at a target trial emulation on transplantation. Do older pts benefit from kidney transplant? What if donation is after: CV death or brain death? What if donor is a standard (SCD) or extended (ECD) criteria donor? #NephTwitter nephjc.com/news/transplantem…
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12 years of #NephJC. Countless papers discussed, ideas challenged, and friendships made. 🩵No paywalls. No pharma funding, just a community that believes in free, independent nephrology education. 🌟We need your help to keep it going. Please donate nephjc.com/news/2026/9/8/nep…
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Can tolvaptan keep up with 3% saline? This within-subject study in healthy volunteers delivered a surprising answer - and a few eyebrow-raising physiology twist. Dive in #NephJC ✍️ by @DrSaiVani1 nephjc.com/news/tolvaptanhyp…
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