Thrilled to announce that our paper (w. fantastic @richardneher and Liam Shaw) is now published on Molecular Biology and Evolution 🎉
academic.oup.com/mbe/advance…
Curious about how fast the genome of E.coli evolves structurally (gains, rearrangements...) ? 🧬
Marco Molari retweeted
The @KITP_UCSB QBio course on mobile elements was amazing 🩵 With excellent projects led by @PaulTurnerLab, Roberto Kolter, @jemersonmicro, @richardneher, @NimwegenLab, @benjaminhgood (+ me). Course began with a wetlab bootcamp, Dallas Mould demonstrating the first experiments..
Marco Molari retweeted
Daria Frolova's paper in plasmid relatedness now out in MGen! She uses rearrangement distances & shared seq content to build a relatedness network of plasmids, identifies hubs which are likely transposons, and then clusters related plasmids.
microbiologyresearch.org/con…
@MicrobioSoc
First paper from my student Daria Frolova's PhD now on biorxiv:
biorxiv.org/content/10.1101/…
The key question: plasmids change structurally ~as fast as they mutate, so how can we decide whether 2 plasmids are "the same plasmid" for epi purposes?
1/n
Marco Molari retweeted
One of the reasons I've been quiet on Twitter for a few months is because I've been working on something big - something I'm really happy to share now!
Pathoplexus.org
A new, open-source database for pathogen sequence sharing. 👐🧬🌎
1/12
Marco Molari retweeted
It has been public for a while, but with #VoM2024 starting, today is as good as any to introduce our new tool phage genome annotation tool Phold. Phold uses structural homology to assign functions to phage proteins (1/n)
Marco Molari retweeted
Ever wondered how fast accessory genome dynamics of bacteria really is?
In a new preprint we (@mrcmolari, Liam Shaw) explore how rapidly E coli picks up genes horizontally, breaks genome synteny, etc..
biorxiv.org/content/10.1101/…
For a thread by Marco see
mstdn.science/@mrcmlr/112772…
Marco Molari retweeted
First paper from my student Daria Frolova's PhD now on biorxiv:
biorxiv.org/content/10.1101/…
The key question: plasmids change structurally ~as fast as they mutate, so how can we decide whether 2 plasmids are "the same plasmid" for epi purposes?
1/n
Marco Molari retweeted
If any non-UK folk with (or soon to have) a PhD are interested in applying for a Newton International Fellowship to work with me at the University of Bath (UK) on pangenome algorithms for bacteria and/or plasmids, do get in touch!
Deadline 13th March!
royalsociety.org/grants-sche…
Marco Molari retweeted
Two PhD positions for #plasmid evolution research are open in our group: 1) Computational evolutionary microbiology and 2) Microbial evolutionary genetics. Application deadline: 10.3.24. Details in evoldir: evol.mcmaster.ca/brian/evold… @trans_evo @_K_E_C
Marco Molari retweeted
In particular we've got space on the fantastic Pathogen Phylogenetics and @nextstrain course, and would love to see you there!
I've you've ever wanted to dip into phylo & learn how to run Nextstrain, here's a great chance in a beautiful place!
Register, register, register!
There are still a few places left at the #SwissEpidemiologyWinterschool in beautiful Wengen!
epi-winterschool.org/program…
Marco Molari retweeted
ggCaller paper now out in its final form
genome.cshlp.org/content/33/…
Call your genes, get your pangenome
(and a great cover thanks to laurenbellcreative.com/)
Marco Molari retweeted
Recruiting PhD students for Oct 24 start at University of Bath. Fully funded for UK students only. If interested in developing data structures/algorithms for bacterial genomics, or exploring plasmid epidemiology, or ML/AI on bacterial/phage geno/pheno data, give me a call 1/n
Marco Molari retweeted
I have an open postdoc in my group: embl.org/jobs/position/EBI02…
To work on either modelling or method development, but with a lot of flexibility in project choice. Please contact me if you are interested
Marco Molari retweeted
👩🏻🔬New **PostDoc** Opportunity!👨🏾🔬
My new Epidemiology & Virus Evolution (EVE) group at @SwissTPH🇨🇭 is looking for a PostDoc in evolution & phylogenetics of respiratory viruses 🦠🌳
Interested? See here for more details & to apply!
jobs.swisstph.ch/Vacancies/9…
Please share! 😁
Marco Molari retweeted
👨🏽🎓New PhD Opportunity👩🏿🎓!
My new Epidemiology & Virus Evolution (EVE) group at @SwissTPH 🇨🇭is looking for a PhD student in the evolution of phylogenetics of respiratory viruses 🦠🌳.
Interested? See here for more details & to apply!
jobs.swisstph.ch/Vacancies/9…
Please share! 😁
Marco Molari retweeted
Huge congrats to @richardneher for receiving the 3rd Symposium for Emerging Viral Diseases @gcevd Award! So well deserved for tireless hard work during the pandemic and on @nextstrain!
For his award lecture he will speak on adaptive evolution in #influenza & #SARSCoV2.
Marco Molari retweeted
Since its emergence in late 2019, #SARSCoV2 has diversified into multiple distinct variants.
In a new preprint, I quantify evolution within these variants and compare it to the process that gave rise to these variants.
biorxiv.org/content/10.1101/…
1/N
Marco Molari retweeted
So excited to announce that we have a definitive program for the "QBIO - Innate and Adaptive Recognition of Antigens and Neoantigens" colloquium! Have a look at our amazing panel of speakers at sites.google.com/view/qbio-i…. Registrations and abstract submission are open!
