Dopamine. Science. Technology. Reason. Photography. Baking. Films. Psych Prof @UWpsych
Madison, WI
Joined August 2010
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My dad—arguably the best in the world—has sailed away. He was an advocate of science, a caring cardiologist, and a history enthusiast. He loved telling jokes and making people laugh. I will do the same: laugh and make laugh, until we meet in the deep blue... So it goes...
Indeed, it's an exciting new tool! Congrats to all. Cannot wait to start using the setup...
This is something we are very excited about. @lodder_bart led this development project collaborating with @LinTianPhD lab. The technology makes lifetime photometry easy and, with the new dopamine sensor, allows measurements of phasic and tonic DA in vivo
biorxiv.org/content/10.1101/…
Ali Mohebi retweeted
Pls chk out the Bruchas lab's new preprint "Endocannabinoids facilitate transitory reward engagement through retrograde gain-control". Congrats @DavidJMarcus2 @cloverpharm @StellaLab11 @Graphtablet & many other colleagues. biorxiv.org/content/10.1101/…
I’m excited to share the most recent study from the @mbruchas lab, which represents the culmination of my postdoctoral work, and serves as the platform for my future research programs investigating the in vivo role of the endocannabinoid signaling system!
biorxiv.org/content/10.1101/…
Ali Mohebi retweeted
(1/7) Far-red dopamine sensor is coming! Excited to introduce our chemigenetic DA sensor, HaloDA1.0! #Dopamine #FarRedSensors, #GRAB biorxiv.org/content/10.1101/…
Ali Mohebi retweeted
Excited to share work from Twitter less Juan Enriquez-Traba, grad student from the lab. Juan and the team demonstrate that dopamine regulates differential aspects of reward, motivation vs reinforcement, via co-expressed D3 and D1 receptors
nature.com/articles/s41593-0…
Imagine your favorite top level admins at your school. Who court Epsteins to meet their next fundraising goals. Who care more about the alphabet initiatives than the people the alphabet belongs to. Those have taken control of the Democratic party. And sure, pardon your son.
Two favorite friends of mine talking science 😊
Every neuron in your brain (every cell in your body!) has the potential for universal computation. @theHessam describes why that's important, and one way RNA, and it's secondary structure, could have evolved that ability using combinatory logic.
braininspired.co/podcast/199…
Ali Mohebi retweeted
My paper is out!! 🎉
"Opponent control of reinforcement by striatal dopamine and serotonin", @Nature
Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain 🧠
THREAD ⬇️
1/n
Ali Mohebi retweeted
The first piece of work from my PhD has now been uploaded to biorXiv! Short 🧵below:
Hunger modulates exploration through suppression of dopamine signaling in the tail of striatum biorxiv.org/cgi/content/shor… #biorxiv_neursci
Kindness trumps excellence. My dad, a farmer’s son who became a pioneering cardiology professor, was remembered after his passing not for his academic/career achievements but for his acts of kindness. It goes to show that kindness outlasts success. Kindness is timeless...
An interview with him (in Farsi) where he shares some of his thoughts and ideas...
youtu.be/TJgtHuJGgwo
Thank you all for your messages. It takes a village to uplift sorrow. I feel so lucky to be surrounded by villagers...
The Fountain is perhaps the best depiction, both visually and musically, of death and humanity's helpless struggle against it, ultimately leading to salvation through acceptance. Listen to the OST for me
youtube.com/watch?v=C3skXjCm…
Madisonians! I am psyched about Psych 711. It is the first course I have ever taught in a psychology department. Join me; let's read and judge(!) papers, have some fun, and learn some skills together. Here's a greeting from my (non-oval) office to you.
youtube.com/watch?v=C2MYSKxr…
And here's a very early draft syllabus, just in case:
chain-weaver-eb6.notion.site…
It may surprise the tax payer, but I work for a company that thinks “because the exact same item was 60% cheaper there” is not a justified reason to pick vendor A over the company approved (read favorite) vendor. I suppose research dollars aren’t real money.
I am giving a talk on Nov 7th. Help me pick a title (Polls close on Nov 6th).
:: Spatio-temporal dopamine dynamics for learning, motivation, and beyond
:: What shall we do now? A eulogy for science, wisdom, and hope
Solid paper (as expected) from Arif and co. Congrats, team!
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Just watched Ken Loach's final film. It's not his best. But it reminds you what a good movie should be about... And what decent moral values are like. This is what we need more of, in these dark days. Thank you good sir, for all the beauty and compassion, for all these years
The latest @berke_lab paper in @PNASNews by my bff @DuhneMariana (with some contribution by yours truly) on cholinergic pauses in the striatum and the dopamine signal... What does the silence mean?
pnas.org/doi/full/10.1073/pn…
In a remarkable 113-page supplementary document, she meticulously presents the rasters and responses of every single tagged cholinergic she recorded from (data and code also available).
pnas.org/doi/suppl/10.1073/p…
