@modoslab

Imperial College Research Fellow researching precision medicine in inflammatory bowel disease using network biology and modelling

 London
Joined July 2023
  • Tweets107
  • Following225
  • Followers86
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DISCOVER-ME partners meet in Valencia for project kick-off discover-me.eu/discover-me-p… #DISCOVER_ME #research #mecfs #HorizonEurope #BiomedicalResearch
Group photograph of DISCOVER-ME project partners attending the consortium kick-off meeting in Valencia, Spain, in October 2026

ALT Group photograph of DISCOVER-ME project partners attending the consortium kick-off meeting in Valencia, Spain, in October 2026

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Day 1, Session 1 of #BREMC15 explores Systems Biology & AI in ME/CFS research, chaired by @TamasKorcsmaros, with talks from Dezso Modos, Veronika Kedlian & Marek Ostaszewski. Advancing data-driven biomedical research in #MECFS. @Invest_in_ME
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Ready to kick off two days of ideas, collaboration, and new connections at the YoungEMERG Symposium 2026. We are excited to welcome participants and speakers from across the community. — let’s begin! 🚀 #YoungEMERG2026
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📣 Registration for the YoungEMERG Symposium 2026 has been extended until 14 May! Don’t miss two days of talks, networking, and discussions on ME/CFS research — plus our Cambridge evening activity with punting and dinner ✨ 📩 Register via: [email protected] #YoungEMERG
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📣 YoungEMERG Symposium 2026 — registration now open! 📅 25–26 May 2026 | Hinxton Hall, Wellcome Genome Campus Register: youngemerg.com/yemerg07reg.s… #YoungEMERG #MECFS
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𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗠𝗘 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗪𝗲𝗲𝗸 𝟮𝟬𝟮𝟲 25-29 May Cambridge, UK 5 days of biomedical ME #research 20 Years Investing in ME Research to Discover #mecfs Young Researchers + #BRMEC15 + #IIMEC18 + #EMERG2026 #IMECW2026 @YoungEmerg @euromeresearch
Poster for UK charity Invest in ME Research's International ME Conference Week 2026 featuring a globe embedded in a DNA helix

ALT Poster for UK charity Invest in ME Research's International ME Conference Week 2026 featuring a globe embedded in a DNA helix

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This week’s new issue of #ScienceSignaling has arrived! A study reveals how fetal cells could activate maternal natural killer cells during early pregnancy, systems immunology reveals cytokine targets in ulcerative colitis, and more. scim.ag/4ko4K0k
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Replying to @KorcsmarosLab @ibdleuven @bverstockt @NickPowellLab @modoslab @johanne_brooks @ImperialMDR
We were honored to get an Editorial at the journal highlighting our study and its implications. We are grateful for the great Claudio Fiocchi and Dimitrios Iliopoulos for their insightful summary. academic.oup.com/ibdjournal/…

Rewiring of Transcription Factor Binding: Another Piece of the Intricate Puzzle of IBD Pathogenesis

Whatever stimuli come from the global environment (the exposome), being they exogenous like microbial, dietary, and chemical ones, or endogenous, like gene

academic.oup.com
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Our findings show how genetic variation reshapes cellular signaling in #IBD (see two patient-specific networks 👇), providing a foundation for #PersonalizedMedicine. Collaborative work with @ibdleuven @bverstockt @NickPowellLab @modoslab @johanne_brooks 🙌 From @ImperialMDR
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👀 check out projects 1 & 6 on the list: 1️⃣ Multicellular molecular characterisation of inflammatory bowel disease 6️⃣ Designing Efficient Single-Cell Perturbation Experiments with Lab-in-the-Loop AI Agents 📅 Application deadline is 30th September ❗
EMBL-EBI Jobs@EMBLEBIjobs4 Aug 2025
Postdocs: Ready to shape the future of bioinformatics & genomics? The 2025 EMBL-EBI | Sanger ESPOD Fellowship is now open! Cutting-edge science, world-class training, and collaborative research await. Apply now embl.wd103.myworkdayjobs.com… #ESPOD #Postdoc
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🎉 The revised version of CORNETO, our unified Python framework for knowledge-driven network inference from omics data, is published in peer reviewed form 🔗 Paper: nature.com/articles/s42256-0… 📖 News & Views: nature.com/articles/s42256-0… 💻 Code: corneto.org 🧵 Thread 👇
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Great to see this work from Shiv Radhakrishnan and colleagues out in #GutMicrobes - using network analysis to explore #microbiome #metabolome interactions in an #IBD inception cohort: doi.org/10.1080/19490976.202… @IHepatology @ImperialMDR @KorcsmarosLab

Deciphering the microbiome–metabolome landscape of an inflammatory bowel disease inception cohort

The gut microbiota contribute to the etiopathogenesis of inflammatory bowel disease (IBD), but limitations of prior studies include the use of sequencing alone (restricting exploration of the contr...

tandfonline.com
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Inspiring few days on how to identify mechanisms for #MyalgicEncephalomyelitis (ME) / Chronic Fatigue Syndrome. #SystemsBiology session w/ @modoslab #Cytokines w/ @martonolbei #organoids & new #Gutonchip + #microbiome platforms @ImpOrganoid @ImperialMDR Thanks for @Invest_in_ME
@invest_in_me (Invest in ME Research) 🇪🇺@Invest_in_ME25 May 2025
Distinguished line-up for #BRMEC14 Colloquium Investigating the Mechanisms of Myalgic Encephalomyelitis— from pathogenesis and aetiology to treatment innovation, integrating systems biology and clinical research. investinme.org/brmec14agenda… #mecfs #research #IMECW2025 @euromeresearch
Image for #BRMEC14: Investigating the Mechanisms of Myalgic Encephalomyelitis: From Pathogenesis and Aetiology to Treatment Innovation – Integrating Systems Biology and Clinical Research BRMEC14 logoThe 14th Biomedical Research into ME Colloquium (#BRMEC14) brings together leading international scientists and clinicians focused on Myalgic Encephalomyelitis (ME) (also referred to as ME/CFS) and related conditions such as Long Covid. Building on thirteen years of successful collaborative events, #BRMEC14 continues to advance the understanding of ME by fostering knowledge exchange and encouraging international collaboration.

ALT Image for #BRMEC14: Investigating the Mechanisms of Myalgic Encephalomyelitis: From Pathogenesis and Aetiology to Treatment Innovation – Integrating Systems Biology and Clinical Research BRMEC14 logoThe 14th Biomedical Research into ME Colloquium (#BRMEC14) brings together leading international scientists and clinicians focused on Myalgic Encephalomyelitis (ME) (also referred to as ME/CFS) and related conditions such as Long Covid. Building on thirteen years of successful collaborative events, #BRMEC14 continues to advance the understanding of ME by fostering knowledge exchange and encouraging international collaboration.

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"I often wonder… Why isn’t this therapy working for my IBD patient?" Then I remind myself: It could be… ❗ Too Late – Delayed start of effective therapy ❌ Wrong Choice – Misaligned mechanism of action or incorrect diagnosis 💊 Not Taking Medication – Non-adherence is real ⬇️ Not Pushing Hard Enough – Suboptimal dosing or no T2T strategy Step back. Reassess. Personalize. The right therapy at the right time can change everything. Created by @ibdtweets | Tauseef Ali, MD #IBD #Crohns #UlcerativeColitis #Gastroenterology #TreatToTarget #PrecisionMedicine
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🚀 The Interdisciplinary Signaling Workshop 2025 is taking shape! 🔬✨ A unique multidisciplinary program connecting #ECR & #PhD students with world-leading experts in #IBD, #microbiome, #organoids, & #PrecisionMedicine Details & registration by 4 April: signalingworkshop.org
KorcsmarosLab@KorcsmarosLab11 Mar 2025
I’m organizing another Signaling Workshop this July for #PhDs #ECRs & @Y_ECCO_IBD! ✅ Interdisciplinary: #IBD, #cancer, #microbiome, #organoids, #multiomics ✅ Networking: Leading experts from diverse fields ✅ Group projects 🔗 signalingworkshop.org Check video from 2023👇
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I’m organizing another Signaling Workshop this July for #PhDs #ECRs & @Y_ECCO_IBD! ✅ Interdisciplinary: #IBD, #cancer, #microbiome, #organoids, #multiomics ✅ Networking: Leading experts from diverse fields ✅ Group projects 🔗 signalingworkshop.org Check video from 2023👇
KorcsmarosLab@KorcsmarosLab24 Jul 2023
Thanks to many attendees & sponsors👇#ISW2023 has been a 'very different workshop'! #Signaling23 We had terrific talks, great posters, fantastic teamworks, Knights tournaments + Catamaran race 10 children w/ parallel/own programs See you (again) in 2025! signalingworkshop.org
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Looking forward to another great course!
Imperial CPD@ImperialCPD10 Mar 2025
Hands-on #Data #Analysis for #Metabolic Profiling is back at our Hammersmith campus 9-13 June! Training in processing & analysing #metabolomics data from LC-MS & NMR technologies. Early bird until 9 May. @tebbels @ImperialMDR @ImperialMed For more info 🔗imperial.ac.uk/continuing-pr…

Hands-on Data Analysis for Metabolomics

This 5 day course provides a comprehensive overview of data analysis for metabolomics studies focusing on data from NMR spectroscopy and Liquid Chrom...

imperial.ac.uk
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modoslab retweeted
ISCB News
@iscb12 Feb 2025
Your work can inspire the future of bioinformatics. Submit your abstract for ISMB/ECCB 2025 and present your research as an oral or poster presentation.

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Very proud of our clinical PhD fellow, John Thomas @MRC_LMS to win the Top15 best talk award #ECCO2025 - from >1000 abstracts/~200 talks 👏 He showed how genetics can predispose to #IBD due to patient-specific environmental signal changes W/ @modoslab @NickPowellLab @ibdleuven 🙌
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Excited to share our work on UC cytokine networks at #ECCO2025. Come by poster P0104 if you are interested in: - how cytokines regulate each other in UC - the role of TL1A in treatment-naive UC - how we could use this approach to identify new drug targets
KorcsmarosLab@KorcsmarosLab25 Sep 2024
New preprint ⭐️ providing insight into #UlcerativeColitis! With single-cell transcriptomics data we mapped complex cytokine networks to uncover key interactions and potential therapeutic targets. @modoslab @NickPowellLab @ImperialMDR Preprint: biorxiv.org/content/10.1101/… Thread👇

Decoding Cytokine Networks in Ulcerative Colitis to Identify Pathogenic Mechanisms and Therapeutic...

Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract characterised by dysregulated cytokine signalling. Despite the advent of advanced therapies targeting cytokine...

biorxiv.org
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