Innovative UK MND clinical trial from Euan MacDonald Centre for MND research at @EdinburghUni. Designed alongside people with MND. Searching for new treatments.

Edinburgh, UK
Joined February 2021
MND-SMART is a ground-breaking multicentre platform trial accelerating the search for safe and effective treatments for motor neuron disease. Working alongside pwMND, we’re evaluating multiple potential therapies to identify those that can slow or stop disease progression.
4
7
398
We're pleased to share that we have opened a new trial location at the Rob Burrow Centre for MND. Read more ➡️ edin.ac/4gAd8YR Register your interest to participate in the trial ➡️ edin.ac/490fmPk
1
6
13
509
MND-SMART Amantadine Stage 2 Interim Analysis Results: Amantadine doesn’t slow MND - now we know, and now we move forward. Read more: edin.ac/4cnN3fp #ALS #MND #trial
1
4
2
6
1,565
We’re very proud to be working closely with the Motor Neurone Disease Association to increase equity of access and opportunities for people living with #mnd #als to participate in clinical #trials
We're proud to announce that we have trebled our investment in the unique MND-SMART trial platform which is driving faster research into potential treatments for motor neurone disease. Read more. 🔗mndassociation.org/media/lat…
3
7
252
⭐️The winter edition of our biannual newsletter is out now!⭐️ Take a look 👉edin.ac/48QllUW Subscribe on our website to receive the next newsletter directly by email: edin.ac/44K2zxB
4
138
We’re delighted to share that MND SMART is now open for recruitment at Imperial College Healthcare NHS Trust. A very warm welcome to the Imperial team! Read more 👉 edin.ac/47zZLn5 Register your interest to participate in MND SMART👉 edin.ac/490fmPk #ALS #MND
3
215
We’re delighted to announce that MND-SMART is now open for recruitment at Hull Royal Infirmary, offering opportunities for participation to people living with motor neuron disease across the Hull and Humber Region. 🔗 mnd-smart.org/news/mnd-smart…
1
3
455
⭐️The brilliant and dedicated research team at the Southampton General Hospital Trial Centre have now randomised >50 participants to MND-SMART!⭐️ Read more 👉 mnd-smart.org/news/jul-2025-… #MND #ALS #clinicaltrial
2
5
395
We're excited to welcome a new Group Leader to the UK DRI! 🥳🙌 Prof @suvankarpal joins our Edinburgh Centre, where he aims to deliver a streamlined approach to take mechanistic understanding of neurodegeneration into evidence-based clinical trials👉buff.ly/WOVDlGI
3
3
2
23
3,953
Tacrolimus added as the fourth investigational arm in MND-SMART. MND-SMART uses an innovative #MAMS design to evaluate several potential treatments simultaneously, speeding up the time to identify effective therapies. Read more 👉 edin.ac/4jWf0uM #GlobalMNDAwarenessDay
1
12
3
21
3,023
🔔 New Trial Centre Open 🔔 Led by Principal Investigator Dr Malcolm Proudfoot, York & Scarborough Teaching Hospitals have joined the MND-SMART team. Read more here 👉mnd-smart.org/news/mnd-smart… #MND #ALS #MNDSMART #MAMS
1
3
10
1,157
Uplifting afternoon at the College of Medicine & Veterinary Medicine, University of Edinburgh Staff Recognition Awards. Very proud the @mndsmart team were awarded the Collaboration & Partnership Award. Fortunate to work alongside inspiring colleagues & people with #MND #ALS🙏🏾🥇
1
2
1
14
942
Congratulations to the fantastic team at Birmingham for delivering equity of access to trials for people living with #MND. Supported by the wonderful @ADFoundationUK, Birmingham serves a diverse population, is a major regional recruitment hub, and one of 23 of our UK sites.
1
3
1
9
509
Our newsletter is back! Find out what’s been happening in MND-SMART over the past year with our Spring 2025 Newsletter: edin.ac/41OJ6td Join our mailing list to receive our bi-annual e-newsletter, showcasing all the latest trial updates: mnd-smart.org/news/newslette…
1
1
6
492
Platform trials have led to a significant step change in how we identify potential new treatments for #als #mnd Thank you to @ALSMNDAlliance for inviting @suvankarpal to present an update on progress we’re making alongside the #EXPERTS & #HEALEY platforms youtu.be/cg1Yon70eZ8?si=vHYT…
1
2
11
681
ALS/MND Platform Trials Update | March 19, 2025 📊 Many thanks to HEALEY, EXPERTS ALS and SMART! They will update us on their approach, recruitment, trial eligibility and their latest news. Appreciation to moderator, Martina de Majo. 🙏 👉 Register now: als-mnd.org/events-programs/…
4
5
419
Incredibly grateful to @mndsmart for leading this initiative and a warm welcome and huge thanks to our new Davidson Nurses 🙏🥰
We are thrilled to launch our new 'Davidson Nurses' initiative in partnership with the @ADFoundationUK This special collaboration has established five regional hubs across the UK where dedicated nurses are working to promote equity of access to MND-SMART. mnd-smart.org/news/mnd-smart…
1
6
269