Earl K. Miller (@MillerLabMIT) header
Earl K. Miller (@MillerLabMIT) profile picture

Earl K. Miller

@MillerLabMIT

Picower Professor of Neuroscience at MIT https://xitter.cf/t.co/UoEeD2FzEY Co-founder, Neuroblox https://xitter.cf/t.co/o6wosMSGen

 Cambridge, MA
ekmillerlab.mit.edu/
Joined May 2011
  • Tweets11.2K
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  • Followers47.4K
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Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)Photo by Earl K. Miller (@MillerLabMIT)
Earl K. Miller retweeted
Biyu Jade He (@BiyuHe) profile picture
Biyu Jade He@BiyuHeNov 5
Nice work! See this paper from our lab earlier this year showing that one-shot perceptual learning-induced activity change onsets in IT before early visual ctx, the underlying plasticity likely residing in IT, and an ANN model capturing this phenomenon. nature.com/articles/s41467-0…
Neural and computational mechanisms underlying one-shot perceptual learning in humans

Neural and computational mechanisms underlying one-shot perceptual learning in humans

Nature Communications - In one-shot perceptual learning, what we see can be dramatically altered by a single past experience. Using psychophysics, fMRI, iEEG, and DNNs, the authors identify neural...

nature.com
Gabriel Kreiman (@gkreiman) profile pictureGabriel Kreiman
@gkreimanNov 4
Single trial learning: Same pixels, new perception. 🧠 Researchers uncovered the neuronal mechanisms underlying the “aha!” moment. We recorded the activity of >1,000 human neurons to explore how rapid learning reshapes what we see—and what AI might learn from it. The picture didn’t change. The brain did. Armendariz et al, Nature Neuroscience 2026. Read more here: kreimanlab.com/code/rapid-vi…
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Mentees, colleagues, friends share remembrances of Susumu Tonegawa news.mit.edu/2026/sharing-re…
Image from MIT Brain and Cognitive Sciences (@mitbrainandcog)
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Anesthesia doesn’t just dampen brain activity. It reorganizes how waves travel across the cortex, differently for different frequencies. State-dependent, frequency-specific modulation of electrocortical traveling waves by anesthesia doi.org/10.64898/2026.08.11.… #neuroscience
State-dependent, frequency-specific modulation of electrocortical traveling waves by anesthesia

State-dependent, frequency-specific modulation of electrocortical traveling waves by anesthesia

Emerging evidence suggests that cortical activity is organized in traveling waves that coordinate neural activity across space and time. How anesthesia alters these waves remains underexplored. We...

biorxiv.org
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Brain-like robustness likely comes from feedback and randomness working together Robust inference via top-down feedback and neural variability in recurrent vision models cell.com/patterns/fulltext/S… #neuroscience
Robust inference via top-down feedback and neural variability in recurrent vision models

Robust inference via top-down feedback and neural variability in recurrent vision models

Greco et al. show that top-down feedback improves the sensory robustness of recurrent vision models when combined with neural variability via dropout. Neural variability prevents unit-level co-adap...

cell.com
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What can machine learning discover about the nature of emotion? cell.com/trends/cognitive-sc… #neuroscience
What can machine learning discover about the nature of emotion?

What can machine learning discover about the nature of emotion?

The science of emotion increasingly relies on machine learning (ML) in the hope of making objective discoveries that resolve century-long debates. We examine research strategies in two main research...

cell.com
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Interesting. This paper proposes that advanced civilizations are rare because two steps, creating a genetic code and creating language, are difficult. So only a tiny fraction of life becomes advanced enough to travel into space doi.org/10.1016/j.plrev.2026…
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Theta rhythms helps consolidate memories. Theta-frequency sensory entrainment promotes episodic memory consolidation sciencedirect.com/science/ar… #neuroscience
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We are finding that theta acts as a master clock that helps coordinate higher-frequency rhythms. Broschard et al (2026) Theta-based organization of information in the frontal cortex. Cell Reports, in press. Preprint: doi.org/10.64898/2026.06.03.…
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Circuit mechanisms for disentangled representations and generalization in the hippocampus nature.com/articles/s41593-0… #neuroscience
Circuit mechanisms for disentangled representations and generalization in the hippocampus

Circuit mechanisms for disentangled representations and generalization in the hippocampus

Nature Neuroscience - The hippocampus encodes different aspects of experience as disentangled variables, enabling flexible recombination and generalization to new situations. This code is supported...

nature.com
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Earl K. Miller retweeted
PNASNews (@PNASNews) profile picture
PNASNews@PNASNewsOct 29
Honoring Susumu Tonegawa, a pioneering molecular biologist whose discoveries transformed immunology and neuroscience. A 1987 Nobel laureate, he advanced our understanding of antibody diversity, learning, and memory. Read the PNAS Retrospective: ow.ly/zORA5102cfh
Honoring the life of Susumu Tonegawa

ALT Honoring the life of Susumu Tonegawa

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It’s not which neurons fire. It’s the geometry of their activity patterns. The piriform cortex doesn’t just store odor “labels.” It continually reshapes that geometry to encode odors. Representational manifolds in olfactory cortex doi.org/10.1016/j.conb.2026.… #neuroscience
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A recent example of this subspace geometry: Li, H., Chrysanthidis, N., Brincat, S.L., Rose, J. and Miller, E.K. (2026) Neural subspace reorganization reflects value-based decision making. iScience, doi.org/10.1016/j.isci.2026.…
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🪱🪼🪰There's still limited time to register for our daylong symposium "Comparative Neuroscience: Lessons from Biodiversity" Nov. 4. docs.google.com/forms/d/e/1F… @MITBiology @mitbrainandcog @ScienceMIT @MITevents
Image from MIT Picower Institute (@MIT_Picower)
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The brain appears to keep ordered lists in separate, low-dimensional position-based “slots” in its activity patterns, not by replaying them one at a time. Neural subspaces encode sequential working memory without detectable neural sequences nature.com/articles/s41467-0… #neuroscience

Neural subspaces encode sequential working memory without detectable neural sequences

Nature Communications - This study finds that the brain maintains sequences in working memory by organizing items according to their position in a low-dimensional neural subspaces, rather than by...

nature.com
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Nice review and discussion Visual attention: Defining the origin of the current terms of engagement link.springer.com/article/10… #neuroscience
Visual attention: Defining the origin of the current terms of engagement

Visual attention: Defining the origin of the current terms of engagement

Attention, Perception, & Psychophysics - Our environment bombards the mind with far more visual information than can be processed. Because of this overload of information, our minds focus on...

link.springer.com
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Earl K. Miller retweeted
Simons Foundation (@SimonsFdn) profile picture
Simons Foundation
@SimonsFdnOct 26
We're remembering the transformative leadership of renowned neuroscientist Gerry Fischbach, who died Sunday at 87. Fischbach founded the Simons Foundation Autism Research Initiative (SFARI) in 2006, inspired the launch of our neuroscience collaborations, and provided invaluable guidance as a member of our board. We will miss him dearly. bit.ly/4stovHV
Remembering Gerry Fischbach: A Pioneer in Neuroscience and Autism Research

Remembering Gerry Fischbach: A Pioneer in Neuroscience and Autism Research

The Simons Foundation mourns the death of Gerald D. Fischbach, who died Sunday at 87. Fischbach, who went by Gerry, was a renowned neuroscientist whose transformative leadership at the Simons…

simonsfoundation.org
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Join us Nov. 4 for "Comparative Neuroscience: Lessons from Biodiversity," our Fall symposium! What can we learn from the differences and similarities across the diversity of nervous systems that have evolved? picower.mit.edu/events/picow… @MITBiology #neuroscience
Image from MIT Picower Institute (@MIT_Picower)
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Spatial working memory enhances gamma oscillations in rodent olfactory bulb and medial prefrontal cortex biorxiv.org/content/10.64898… #neuroscience
Spatial working memory enhances gamma oscillations in rodent olfactory bulb and medial prefrontal...

Spatial working memory enhances gamma oscillations in rodent olfactory bulb and medial prefrontal...

Spatial working memory (SWM), a specialized form of working memory that temporarily encodes and retains spatial information, is fundamental to guide animal behaviors, yet our current knowledge of its...

biorxiv.org
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Hey, that's me. L-i-v-i-n Lives in the Labs: Beyond the Bench. Earl Miller instagram.com/p/DezF_YOAFcv/ @MIT_Picower
MIT Picower Institute (@mit_picower) • Instagram photo

MIT Picower Institute (@mit_picower) • Instagram photo

instagram.com
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Brain waves may play a role in distortions of our perception of the passage of time. The sleep-wake circuit plays a role in temporal distortions sciencedirect.com/science/ar… #neuroscience
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