
Co-Founder & Principal @ThirdPlateau. Executive Director of Democracy Funders Network. Social impact strategist. Food addict. Global circumnavigator.
San Francisco, CA
Joined April 2009
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Mike Berkowitz retweeted
This has quietly been a miracle month in medicine.
In the last 5 weeks we’ve got news on:
- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors
This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.
Mike Berkowitz retweeted
Simply horrifying.
We must have the highest tolerance for opinion and absolutely no tolerance for violence.
BREAKING: Charlie Kirk was shot during an event at Utah Valley University today. Details of the incident are still unfolding.
Political violence is never an acceptable response to speech. Free speech allows us to settle our differences peacefully and is essential to a free and democratic society.
Our thoughts are with Charlie Kirk and his family.
Read this post from @YaelEisenstat. Egregious and unacceptable for our government to be acting this way.
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This is totally wild.
The last living grandson of President John Tyler has died.
Harrison Ruffin Tyler was born in 1928 and died in 2025.
His grandfather, the 10th President of the United States, was born in 1790 and died in 1862.

ALT Alt-text: A side-by-side image featuring a painted portrait of President John Tyler on the left and a contemporary photograph of his grandson, Harrison Ruffin Tyler, on the right. John Tyler is shown in a formal 19th-century black suit, seated and gazing to his left with a dignified expression. Harrison Ruffin Tyler, elderly with gray hair and wearing a white shirt and gray sweater, looks into the camera with a gentle expression, highlighting the striking generational link between them.
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I am deeply concerned about the ways in which philanthropy and civil society more broadly will be inappropriately targeted by the incoming administration and its allies. philanthropy.com/commons/tru…
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Mike Berkowitz retweeted
If we’re going to take on Trump, Republican extremists, and move our country forward, the Democratic Party needs to be stronger. I'm running for Chair of the Democratic National Committee to unite the party, fight everywhere, and win. Join me. 🧵
Mike Berkowitz retweeted
Nope. Nope. Nope. Trump won fair and square. Follow Harris's lead. She conceded. It's over.
Mike Berkowitz retweeted
No, I am not going to write about what Harris should have done, and pretend that my personal biases/preferences have some kind of universal significance
Mike Berkowitz retweeted
I am begging General Kelly to call a press conference and talk straight to the American people about all the things he saw and heard.
Mike Berkowitz retweeted
This is disgraceful. If your idea of protest is aligning yourself with a brutal terrorist group, you have lost your way. You are terrorizing Jews and you are doing great harm to the people you’re claiming to support.
Mike Berkowitz retweeted
And if you’re with us, donate to her campaign here:
secure.actblue.com/donate/so…
Mike Berkowitz retweeted
My fellow Democrats, I have decided not to accept the nomination and to focus all my energies on my duties as President for the remainder of my term. My very first decision as the party nominee in 2020 was to pick Kamala Harris as my Vice President. And it’s been the best decision I’ve made. Today I want to offer my full support and endorsement for Kamala to be the nominee of our party this year. Democrats — it’s time to come together and beat Trump. Let’s do this.




















