International platform for updates on Cerebral Microbleeds 🧠🩸– an MRI marker of cerebral small vessel disease. #microbleeds 👨💻
Sweden
Joined August 2015
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Cerebral microbleeds retweeted
💡 Glad to share our latest paper published in #JAHA on long-term blood pressure fluctuations and their association with cerebral amyloid angiopathy (CAA)-related ischemic brain lesions. 🧠💥
Cerebral microbleeds retweeted
🚨New paper:
Everything you actually need to know about Cerebral Amyloid Angiopathy (CAA) — in 10 clinical takeaways. 🧠💥
🙏 Grateful to @StrokeAHA_ASA for the invitation — and for the intellectual freedom to share my expert perspective.
🔗ahajournals.org/doi/10.1161/…
🧵 to follow soon
#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
Cerebral microbleeds retweeted
Boston University and Radboud University researchers have secured a $9M Leducq Foundation grant to advance molecular neuroimaging for cerebral amyloid angiopathy (CAA).
radiologybusiness.com/topics…
Cerebral microbleeds retweeted
🧠🩸Really excited to share that the @FondationLeducq has awarded a $9M International Networks of Excellence grant to launch TRAFFIC, a BU–Radboudumc co-led initiative focused on advancing understanding, early detection, and diagnosis of cerebral amyloid angiopathy. Grateful to our international team and excited for the opportunity to build a collaborative framework that can move the CAA field closer to earlier intervention and future therapies.
🔗bu.edu/cbr/2026/06/15/9m-gra…
@BU_Tweets @AphasiaLab @BUProvost @BUmedical @The_BMC #NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
Cerebral microbleeds retweeted
🧠Really excited to share that the @FondationLeducq has awarded a $9M International Networks of Excellence grant to launch TRAFFIC, a BU–Radboudumc co-led initiative focused on advancing understanding, early detection, and diagnosis of cerebral amyloid angiopathy. Grateful to our international team and excited for the opportunity to build a collaborative framework that can move the CAA field closer to earlier intervention and future therapies.
Read more👇👇
@BU_Tweets @AphasiaLab @BUProvost
@BUmedical @The_BMC
#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
The Leducq Foundation has awarded Drs. Antreas Charidimou (Boston University) & Marcel Verbeek (Radboudumc) a $9M grant to support their project, “Translational Framework For Innovation in Cerebral amyloid angiopathy (TRAFFIC).”
🔗 bit.ly/4utoym7
@a_charidimou
Cerebral microbleeds retweeted
🩸🧠Clinical MRI framework for cerebral amyloid angiopathy (CAA) diagnosis.
@StrokeAHA_ASA
#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
Cerebral microbleeds retweeted
Our 1st harrowing experience ever.
28 ♀
Post D&C.
After 5D in ICU on venti.
What do we observe?
Cerebral microbleeds retweeted
🩸🧠Cerebral Amyloid Angiopathy: Pillars for management
#WSC2025
🔖 Read our full Guidelines on behalf of the @iCAAassociation & @WorldStrokeOrg via @IntJStroke
🔗journals.sagepub.com/doi/10.…
#WSC2025 #NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
Cerebral microbleeds retweeted
The 2025 @WorldStrokeOrg scientific statement on cerebral amyloid angiopathy (CAA) - a "very prevalent" small vessel disease - is discussed by @a_charidimou at #WSC2025, including stratification of future bleeding risk in probable CAA cases and the role of inflammation
Cerebral microbleeds retweeted
Imaging Pearl 1: COVID-19 SWI MRI with Critical Illness Associated Cerebral Microbleeds
ALT Imaging Pearl 1: COVID-19 with Critical Illness Associated Cerebral Microbleeds
Cerebral microbleeds retweeted
🫀 AFib + prior brain bleed 🧠 or CAA?
🚨New meta-analysis (14 studies, 1,235 pts) finds LAAO may be safe:
✅ Stroke ~2%
✅ Recurrent bleed ~2%
✅ Major bleed ~3%
⚠️ Evidence low — RCTs needed!
#StrokePrevention #AFib #LAAO
@a_charidimou journals.sagepub.com/doi/abs…
Cerebral microbleeds retweeted
🩸🧠Cerebral Amyloid Angiopathy:
Guidelines for Diagnosis and Management
🔖 A Scientific Statement from the @iCAAassociation and the @WorldStrokeOrg via @IntJStroke @SMGreenbergNeur @UCLStrokeRes
☂️These will likely have significant clinical impact by helping to harmonize care for our patients with CAA.
🔗journals.sagepub.com/eprint/…
#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
Cerebral microbleeds retweeted
🚨 New meta-analysis
🩸🧠 In selected patients with AFib &
cerebral amyloid angiopathy / intracranial hemorrhage, 🫀LAAO may be a safe and feasible alternative to 💊anticoagulation.
Excellent work @TheodorosMavri2 and team @IntJStroke!
#NeuroTwitter #Neurology #Neurosurgery #stroke #MedStudentTwitter #FOAMncc #MedTwitter #amyloidangiopathy #FOAMncc #cSVD #Cardiology #CardioTwitter
Excited to present our newly published study/meta-analysis on LAAO in patients with previous ICrH and/or CAA.
Many thanks to my mentor @a_charidimou. Without his guidance this endeavor would not be possible.
I also want to thank Dr Archontakis-Barakakis and Dr Chlorogiannis...
Cerebral microbleeds retweeted
Excited to present our newly published study/meta-analysis on LAAO in patients with previous ICrH and/or CAA.
Many thanks to my mentor @a_charidimou. Without his guidance this endeavor would not be possible.
I also want to thank Dr Archontakis-Barakakis and Dr Chlorogiannis...
Just Accepted!
🫀🩸Systematic review and meta-analysis suggests LAAO may offer safe and feasible alternative to anticoagulation in high bleeding risk AF patients with ICrH/ CAA
👉More RCTs needed to confirm
Read more here!👇
journals.sagepub.com/doi/abs… @TheodorosMavri2
Cerebral microbleeds retweeted
10/
🔹 GRE / SWI (Gradient Echo / Susceptibility Weighted Imaging)
These sequences detect magnetic distortion from paramagnetic substances—like iron, calcium, or blood.
🩸 Blood breakdown = iron = black on imaging
🧠 Use for:
– Microbleeds
– Hemorrhagic conversion
– Cavernomas
– Calcifications
Know your anatomy: iron is naturally present in regions like the globus pallidus.
🧠 The image below shows microhemorrhages in the thalamus and basal ganglia.
Those small, scattered, circular dark lesions are microbleeds.
The iron deposits distort the local magnetic field, leading to a signal dropout on SWI.
Cerebral microbleeds retweeted
@a_charidimou kicks off #ESOC2025 @ESOstroke with a fine talk on application of diagnostic criteria in CAA
Cerebral microbleeds retweeted
🧠Illicit Drug Use & Cerebral Microbleeds in Patients with Acute Ischemic Stroke & Transient Ischemic Attack
👉New study shows association between cerebral microbleeds and cocaine and opioid use
journals.sagepub.com/doi/ful…
Cerebral microbleeds retweeted
⭕️🧠 CAA progression & neuropath staging (CAA=Cerebral Amyloid Angiopathy)
Here is my take👇 which will try to unpack 🧵 in the coming days.
⛱️ CAA is not a single disease and is not uniform
🌂CAA does NOT invariably progress to bleeding as part of it's natural history, but rather there are hemorrhagic/advanced and non-hemorrhagic phenotypes which progress and behave distinctly
🧊 We only see the tip of the CAA iceberg
#NeuroTwitter #NeuroRad #Neurology #Neurosurgery #stroke #MedStudentTwitter #FOAMncc #MedTwitter #amyloidangiopathy #FOAMncc #neuroscience #brain #Alzheimers #Alzheimer #illustration #neuropath #cSVD
xitter.cf/a_charidimou/status/17…
#MondayTip
Cerebral amyloid angiopathy progression:
1🧬Amyloid deposition in cerebral vessels
2⭕️Alterations in vascular physiology
3🚫Non hemorrhagic lesions
4🩸Hemorrhagic lesions
From: doi.org/10.1016/s1474-4422(2…
@SMGreenbergNeur @a_charidimou
Cerebral microbleeds retweeted
⚡️🩸🧠 Practical framework for diagnosing Cerebral Amyloid Angiopathy-related inflammation (CAA-ri)
We frequently discuss challenging CAA-ri cases with colleagues around the world. This framework summarizes key diagnostic features across the CAA-ri spectrum in a clinically useful manner.
via @ANA_journals @GreenJournal
#NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD
Cerebral microbleeds retweeted
🩸🧠Hemorrhagic MRI manifestations of CAA
(CAA=Cerebral Amyloid Angiopathy)
⚫️ Strictly lobar/cortical @microbleeds
🎢 Cortical superficial siderosis
🪱 Convexal subarachnoid hemorrhage
🩸 Lobar intracerebral hemorrhage
🚀More tomorrow at the #WSC23 SVD-CAA session!
#neurotwitter #NeuroRad #MedTwitter #MedStudentTwitter #MedEd #EndNeurophobia #Neurology #Neurosurgery #RadEd #stroke #amyloidangiopathy #FOAMncc #WICH2023
