Kicking off my #PGY1 specialization into #Ophthalmology today at #UofT! Ready to "see" my dreams come into focus and help patients look towards a brighter future. Grateful for this opportunity and excited for the challenges ahead. #Toronto #Residency #EyeCanDoIt #eye #surgeon

We measure IOP sitting up. Patients spend a third of their lives lying down. Our new #Ophthalmology #Glaucoma meta-analysis found a ~3 mmHg rise in supine IOP among glaucoma-spectrum eyes. Whether this increases translaminar stress or drives progression remains unknown for now. doi.org/10.1016/j.ogla.2026.…

An IOP of 16 on iCare isn't necessarily 16 on Goldmann. Our new meta-analysis of 5,593 eyes found a small average difference between devices, but substantial variability in agreement. A useful reminder when interpreting IOP in clinic. doi.org/10.1097/IJG.00000000… @JOGJournal

First Wnt-pathway biologic to clear noninferiority in DME (+9.1 and +8.7 vs +11.8 letters at year 1), but no secondary endpoint beat ranibizumab and PDR AEs were 6.7%/6.1% vs 0.9%. If it repairs the barrier rather than suppressing neovascularization, it may end up as a combo, not a swap

If a cure really works, the mechanism may be irrelevant to the patient. But “really works” is what Tao is interrogating. An AI might learn to satisfy our trials rather than cure the disease. We needn’t understand every mechanism; we do need to trust how efficacy is established.

With growing concerns around GLP-1 medications and vision loss, could optic nerve anatomy offer some answers? Proud to share our new 16-centre study in Ophthalmology: crowded discs were common in NAION, regardless of GLP-1 exposure. A cup-to-disc ratio (CDR) ≤0.20 carried 46x greater odds! authors.elsevier.com/a/1noE3…

Can LLMs reliably assess Risk of Bias in RCTs? Not quite - but they may still deserve a seat at the table. Our new @PLOSONE study found that ChatGPT was more conservative than human reviewers, supporting its use as an adjunct rather than a replacement doi.org/10.1371/journal.pone…

New in CJO - meta-analysis of RCTs (n=9,718) examining intravitreal anti-VEGF and respiratory adverse events. No increased risk of COPD vs sham. Differences in lower respiratory events were observed across agents, largely driven by bronchitis, with substantial heterogeneity in adverse event reporting. Findings highlight the need for standardized safety reporting in future trials. sciencedirect.com/science/ar… #Ophthalmology #Retina #MedTwitter #EvidenceBasedMedicine

Comprehensive review of trabecular meshwork–based MIGS highlights consistent IOP reduction, favorable safety profiles, and expanding surgical options for glaucoma management, while underscoring the need for long-term comparative outcomes. @JCM_MDPI mdpi.com/2077-0383/15/4/1490

We tested 4 LLMs on retinal management across 14,400 simulated patients and found treatment recommendations shifted with demographic changes. These models can be useful, but they need to be evaluated beyond average accuracy before they’re ready for deployment Published in @ajo_int doi.org/10.1016/j.ajoint.202…

New in AJO International: we mapped what patients actually ask Google about ocular cancers (uveal melanoma, retinoblastoma, ocular surface tumours). Commercial pages dominate; government sites are most transparent… and still too hard to read. doi.org/10.1016/j.ajoint.202… @ajo_int

Ectropion can be stubborn. We reviewed the standard toolkit - and added a practical adjunct: superotemporal skin transposition (STS) for tarsal/recurrent ectropion. Quick add-on, strong vector, nice early outcomes. mdpi.com/2077-0383/14/3/827 @JCM_MDPI #Oculoplastics #EyeSurgery @brendantao @EdselIng