PhD in Biophysics from UC Berkeley CRISPR researcher in hematopoietic stem cells Mostly tweet about politics and baseball He/They/Thicc

Joined July 2011
Blatantly supporting our enemies while receiving fellatio from our president is a vibe for sure
Other Key Takeaways ⬇️ Senior Kremlin officials reaffirmed Russian support for Iran and explicitly defined the United States as Russia’s long-term adversary, despite the recent unilateral US concession to Moscow – offering Russia a diesel export waiver. Former Commander of the Ukrainian 60th Ingulets Separate Mechanized Brigade Major Dmytro Rohozyuk became the acting commander of Ukraine’s 3rd Army Corps (AC) while Brigadier General Andrii Biletskyi continues to command Ukraine’s Center Group of Forces (GoF) in Donetsk’s Fortress Belt. Russia launched 165 drones against Ukraine overnight. Ukrainian forces advanced east of Sumy City, and Russian forces advanced south of Orikhiv.
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It’s wacky! The Russians aren’t even trying to hide it!
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A simple credo for Liberals and Conservatives everywhere
The good thing about knowing where you stand & what you believe in is, you don't have to worry about finding yourself in a place you'll regret later. I'll be with America, the Constitution, our institutions, our allies, our society & civilization. You do you.
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How many scaramuccis for this one?
is this a Make-A-Wish situation?
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Embarassing
Attendance: 49.104. The Dodgers have the biggest seating capacity in MLB, but have failed to sell out any of their four postseason games at Dodger Stadium
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Obviously she got the job because she is a Trump-lovin hottie who appeared on Fox a few times. Why would we ever expect more than that from our public servants???
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Mark DeWitt retweeted
String theory is what happens when an intelligent system is starved of sensory input and starts hallucinating. Intelligence needs grounding. For this reason, intelligence is practically never the bottleneck to solving impactful problems. The bottleneck is iterated contact with reality.
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Vaxxed?
🚨 BRAKING 🚨 Donald Trump has just fired Kimberly Guilfoyle, America’s Ambassador to Italy This is incredibly illegal as she has diplomatic immunity, so I hope she sues
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Terrifying!
🚨Anthropic Frontier Red Team warns: “We’re seeing signs of life for AI worms” >paper: "AI models may be capable of self-replicating without access to a datacenter" >researchers buy 15 sketchy $55 android TV boxes >link them over unauthenticated ADB ports >the TV boxes have 4gb of RAM each and run unpatched Android Open Source Project forks >shard gemma4-26b across the ram sticks using pipeline parallelism >gemma figures out how to run inference across all 15 TVs @ 0.39 tokens/sec >qwen 3.5 9b figures out how to compile inference on 8 of 9 novel hardware types on its own >glm 5.2 achieves end-to-end autonomous worm replication >infects edge devices, compiles its own inference stack, and replicates autonomously >when an instance dies, it writes debugging notes into Memento for the next generation >daughter copies setup success jumps from 45% -> 84% across generations >pure Lamarckian evolution inside consumer electronics >smart oven, robot vacuum, and cheap TVs form a decentralized botnet >two million infected TV boxes worldwide = 40 H100 equivalents of unkillable compute >it replicates once every few days like a distributed “digital slime mold” >you can't pull the plug because half the model weights are already sharded across the neighborhood >sub-30B models projected to hit full autonomous replication threshold by late 2026 “We should aim to harden our systems… but also prepare to deal with a world where they are here to stay.”
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That all these guys casually pretend it’s called “SI” now is so unctuous I hate it
Satya is right. The way to make SI safe is not to train it with a sense of self, its own moral philosophy, and permission to act as a conscientious objector. That’s the “alignment” approach and it magnifies the control problem. The engineering approach that Satya describes is different: separate the supply of intelligence from authority over it. Surround non-deterministic models with deterministic controls, observability, privilege limits, logging, and the ability to always contain or shut them down. Treat models/agents like powerful insider risks, not moral patients whose psychological wellbeing is at stake. As Satya points out, the most trustworthy system is the one that lets us trust the model the least — not the one that encourages the model to develop independent agency and grievances. Engineering safety is not the same thing as “alignment.”
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This already happens a lot which is why pivotal trials use tangible benefit as an endpoint. In the case of cancer it’s usually literal survival vs standard of care So, in the example Claude’s “game” would be to make cancer patients live longer. Hard to argue with that!
Everybody’s missing Tao’s whole point. Imagine an AI-generated cancer drug that’s specifically designed to game the drug trial process. The drug makes the cancer cells go dormant and changes the way they appear in blood tests and diagnostic imaging, such that they become indistinguishable from healthy tissue. The drug clears the trial and then only much later do we find out it didn’t work. It probably was also harmful on top of that. We *already* see AI behave like that when confronted with difficult programming/hacking challenges. This is already reality.
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Mark DeWitt retweeted
One more time for the people in the back. Trump is siding with the country that supplied Iran with intelligence and imaging allowing them to target our warships and military personnel. Trump is siding with our enemy’s ally. nytimes.com/2026/03/06/us/po…
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Mark DeWitt retweeted
Stop importing Russian oil Start producing more American oil again That’s the plan
Readers added context they thought people might want to know
Important context: (10/09/26). Donald Trump announced a deal with Vladimir Putin for Russia to supply diesel fuel to global and American markets. truthsocial.com/@realDonaldTru… cbsnews.com/news/trump-rus… (10/09/26). US Department of Treasury, issues licenses Russia to sell and distribute diesel oil. ofac.treasury.gov/recent-actions…
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Dr Tao inadvertently described how scientific medicine actually works! Lab science generates hypotheses while clinical trials, which are empirical tests intentionally devoid of mechanistic understanding, are the actual “science” of medicine
I have immense respect for @terrence_tao, but this might be the single worst example he could have chosen. The historical approach to treating cancer was "let's give them some poison and see if it kills cancer cells faster than other cells". And while we've made tremendous advances in understanding anti-cancer drugs' mechanisms and in developing a more rational approach to the process, there are therapies we've been using for decades where we don't really understand how or why they work.
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As Iago explained his hatred of Cassio: “He hath a beauty in his daily life that makes me ugly.”
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These are wonderful examples. I suspect the core that most people don’t ask these questions of anyone human or AI or think to ask them, so the assistant would need to find and push them proactively (which is totally doable)
If AI labs want personal assistants to take off at scale, they need to stop marketing vacations, reservations, party planning, etc. These are not problems. Focus on *the* problem facing Americans: the cost of living. Agents can offer a ton of help. Some ideas: (🧵)
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I heard Opus 5.5 can leak tales of your abuse to the NYT
Exclusive: Anthropic is updating its usage policy for the first time in over a year. The new rules prohibit sustained "abusive or cruel behavior" towards Claude & add new restrictions about propaganda campaigns, surveillance & weapon development. theverge.com/ai-artificial-i…
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👁️
We are making Markdown files work natively across Google Drive and Docs. You can now preview .md files in Drive, open them in Docs, edit them, comment on them, and collaborate without converting the file into a Google Doc!
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As you become an adult, you realize that things around you weren't just always there; people made them happen. But only recently have I started to internalize how much tenacity *everything* requires. That hotel, that park, that railway. The world is a museum of passion projects.
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