senior group leader @sangerinstitute. evolutionary geneticist malaria&biodiversity. lifetime member of darwin's posse. obsessive tidepooler. hearts cephalopods.
sanger institute
Joined August 2008
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our latest #MalariaCellAtlas paper is out in @ScienceMagazine today (see science.org/doi/10.1126/scie…) alongside a nice perspective showcasing the value of studying parasites before they become "zombies" (see science.org/doi/10.1126/scie…).
in this thread and this new manuscript, we present an exciting addition to the #MalariaCellAtlas, showcasing a high resolution view of asexual and sexual development of P. falciparum blood stages, as well as the first single cell transcriptomic profile of a natural infection 1/n
i’ve moved over and don’t come here anymore but sharing this since it was originally a twitter call out for survey respondents in case any of you is still active on this platform bsky.app/profile/marakat.bsk…
New pub from the @EarthBioGenome Sample Collection and Processing Subcommittee led by @marakat: "Best-practice guidance for Earth BioGenome Project sample collection and processing: progress and challenges in biodiverse reference genome creation"
academic.oup.com/gigascience…
mara lawniczak retweeted
❓What is #Biodiversity #Genomics?
Our new leaflet explains it in a direct and engaging way - discover more! 🔗biodiversitygenomics.eu/wp-c…
#GenomicsExplained #connections #biology #science #genomes
via @erga_biodiv
very proud of this work -- if you are into malaria or popgen or evolutionary biology or genomics, have a read. and congratulations to the whole team behind this progress to our understanding of malaria mosquito genomic diversity and population structure!
Preprint is out! We investigated the genomic diversity and evolutionary history of Anopheles funestus mosquitoes, one of the main species transmitting human malaria across Africa. Here’s a visual summary. Art by @petrathepostdoc . 1/8
biorxiv.org/content/10.1101/…
very proud of this work and the team behind it -- if you are on the other place, check out this fun thread with science and art bsky.app/profile/marakat.bsk…
Genomic diversity of the African malaria vector Anopheles funestus biorxiv.org/cgi/content/shor… #biorxiv_genomic
mara lawniczak retweeted
We have two open PhD positions in my group at @CRGenomica.
We are seeking candidates with a background in comp. and/or molecular biology, and with a broad interest in evolution, gene regulation, and comparative genomics.
🗓️Apply before Jan 12 here: crg.eu/en/content/training-p…
mara lawniczak retweeted
An exciting opportunity for an early career researcher in ecology and conservation biology @CamZoology - a funded five year Fellowship linked to @ClareCollege jobs.cam.ac.uk/job/48931/ @BES_careers @RoyEntSoc @royalsociety
mara lawniczak retweeted
NEW Sample Collection and Processing GUIDANCE, LIVE on our website now. Check out @marakat's thread --
pleased to share during #BG24 that the @EBPgenome Sample Collection and Processing subcommittee have updated our guidance on all things you need to think about when collecting and preparing specimens that will be used to generate high quality reference genomes (1/6)
pleased to share during #BG24 that the @EBPgenome Sample Collection and Processing subcommittee have updated our guidance on all things you need to think about when collecting and preparing specimens that will be used to generate high quality reference genomes (1/6)
we have also created a community brain dump for the miscellaneous findings we discover along the way that are not quite right for protocols but that might save someone somewhere a good deal of time either by providing a shortcut or (5/6)
by helping someone avoid a path already found to be a dead end. Please benefit from other peoples' miscellaneous discoveries and contribute your own to the new EBP community collection of anecdotes here: tinyurl.com/EBP-Anecdotes - and finally - please RT this thread! (6/6)
mara lawniczak retweeted
For my malaria colleagues - we are trying to grow the GB4 (Ghana) parasite line and are seeing very large schizonts with merozoites that aren't able to egress. Has anyone seen/noted this before for this line?
just a few days left to apply -- @ArnauSebe and I would love to hear from postdocs who have been out of science for a year and would like to come back to science to work on the #BiodiversityCellAtlas -- more info on the Janet Thornton fellowship and available projects below
this year's @sangerinstitute Janet Thornton Fellowship scheme is now open -- this is for postdocs who have left science for 12 months for any reason and want to return -- read more about its history in the thread below, and find out about 8 projects here sanger.ac.uk/about/equality-…
mara lawniczak retweeted
Have you registered for the upcoming BioDiversity Genomics Conference? There is still plenty of time to join in, we highly recommend visit the website to see what is on offer: biodiversitygenomicsconferen…
mara lawniczak retweeted
Working on a very cool @darwintreelife assembly today.
Haplotype resolved assembly of PENTAPLOID Rosa agrestis.
They have asymetric meiosis with two chroms forming bivalents and the other three inherited as univalents through the egg.
Spot the bivalent pairs in the HIC map.
Anopheles nili reference genome! NO COLD CHAIN! 🚫🧊This genome depended on samples that took a week to get from Cameroon to the UK and they were not shipped on ice -- the magic is light squishing in ethanol. One mosquito for DNA and one for Hi-C = scaffold N50 of 75 Mb 🧬🦟
new genome note here: wellcomeopenresearch.org/art… and preservation protocol (squish is the magic sauce) here: protocols.io/view/squishing-…
congrats especially to Sandrine Nsango, @d_ayalag, @dneafse, and @alexmakunin for the work and thanks to @gatesfoundation for the funding