ALT Graphic for 24.09 composed of multiple boxes featuring: associations filtering with logos from ChEMBL, Uniprot, Ensembl, Human Protein Atlas, Gene Ontology, and Reactome, 941 targets with known safety events, FinnGen R11 evidence for 336 associations added to gene burden, 36,740 gene burden evidence in total, OpenAI gpt 4o mini, Azure open datasets, and UI updates for DepMap

ALT Next to a photo of David Hulcoop, Executive Director of Open Targets, text reads: There’s a lot to do and it can be intimidating, but what gets me out of bed in the morning is the progress we’ll make through our current projects and what we will be able to create together with our partners in the future. The quote is from a post on the Open Targets blog: Three reflections from David Hulcoop’s first year as Executive Director

ALT David Hulcoop stands at the front of a lecture theatre. The photo is taken from the back of the theatre so the audience can be seen looking at the projected screen which displays the agenda for the afternoon.

ALT David Hulcoop stands at a lectern, facing out towards the audience and delivering a talk. The screen behind him shows a photo of the three Open Targets directors with the caption: Celebrating our first year.

ALT Annalisa Buniello stands at a lectern, looking back towards the screen which displays the results of an interactive poll. The photo includes the front row of the lecture theatre, with people looking up at the screen.

ALT Three panellists sit at a table with microphones, listening to a question from the audience. Behind them, the screen shows the list of all panellists. To the left, David Hulcoop stands at a lectern.

ALT Graphic showing the highlights of the 24.06 Open Targets Platform release. These read: ChEMBL 24, including European Medicines Agency drug approvals and antibody-drug conjugates (ADCs), Entity List Upload, COSMIC v100, Genomics England, G2P, 9,553 new gene burden evidence from AstraZeneca PheWAS Portal v5

ALT Two men stand on either side of a poster and smile at the camera. The poster title reads: Gentropy, the new Python package for Open Targets Genetics pipelines

ALT A group of over 25 people pose for the photo on bridge connecting two sides of an office building.

ALT A man smiles as he cuts into a sprinkle-covered cake. Text on a screen behind him reads: celebrating 10 years of Open Targets.

ALT Four men laugh while looking at a sheet of paper. They are behind a desk in a meeting room. Green space with trees can be seen in the window behind them.

ALT People sit in a meeting room, behind desks arranged at an angle. They are chatting with each other and laughing.