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I am super grateful that the @NSF's chemistry division, and the American public decided to support my group's research on photochemistry for the next three years! 💰🧪 This is my first major funding award. Thanks goes to all previous group members and mentors over the decades.
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The fascinating story of Thalidomide: how this most notorious drug on the planet, banned in the 1960s, made an incredible comeback and revolutionized the treatment of myeloma.
I will also highlight one person whose role is not recognized: Without Dr. Leif Bergsagel there will be no thalidomide for myeloma.
Read on #MedTwitter
The thalidomide story has many takeaways and lessons.
It shows drug development from bedside to bench and back to bedside.
It shows the power and impact of astute clinicians
It shows the power of investigator courage
The role of serendipity
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Congratulations, Stuart Schreiber and Pete Schultz!
The Welch Foundation is pleased to announce the 2025 Welch Award in Chemistry recipients: Dr. Stuart L. Schreiber of @Harvard and Arena BioWorks, and Dr. Peter G. Schultz of @scrippsresearch.
Both are being recognized for their groundbreaking contributions to the field of chemical biology. Dr. Schreiber is honored for his profound discoveries using chemical probes to understand the chemical machinery of the cell and for developing therapies based on this knowledge. Dr. Schultz is recognized for his pioneering contributions to creating new letters in the alphabet of life, and the leveraging of chemical diversity to discover novel therapeutics and materials.
Each will receive a $500,000 award this October in recognition of their lasting impact in the field of chemistry. Learn more about their work and the award at
welch1.org/news-reports/news…
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Congratulations to Ian Shire for getting the Jacob Kleinberg Award from the @KUChemistry !
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Quick shout out to Asst Prof of Med Chem Zarko Boskovic. He mentors a dual major (chem & biochem) undergraduate student, Ian Shire from Lawrence, who has been selected for a prestigious Courtwright Award for Undergraduate Research Excellence. Congrats to both Ian and Dr. Boskovic
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Interested in radicals and light? Take a few minutes to read what we did here.
pubs.acs.org/doi/full/10.102…
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Manvendra Singh dreamt of becoming a pediatrician before he fell in love with organic chemistry. He still loves children and his young ones inspire him to approach designing diverse and complex compounds in the same way they approach life: with fearlessness, creativity, and awe.
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Taking "induction of proximity" to a new level, Arena BioWorks, a Biomedical Research Institute that just launched in Boston, is bringing academic inquiry and biotech creation under one roof. prnewswire.com/news-releases…
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Excited to be part of the inaugural team at Arena BioWorks @arenabioworks and to work with the amazing scientists assembled there to advance human therapeutics with this new model for scientific innovation and discovery
We're proud to unveil Arena BioWorks, a biomedical research institute with a mission to uncover mechanisms of disease by engaging in basic biological research that will be translated into lifesaving #biotech therapeutics. Learn more: prnewswire.com/news-releases…
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If you are a student or you have students who need to (re)learn concepts from organic chemistry and get instant feedback with lots of examples, you can suggest they try these custom-made "Chemlets":
djavko.github.io/courses/mdc…
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77वें #स्वतंत्रतादिवस पर सभी देशवासियों को बहुत-बहुत शुभकामनाएं।
जय हिंद!
Warm greetings to everyone on the 77th #Independence Day.
Jai Hind!
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Hopping on this rad #ORPGRC post to say that I am so excited to chair next year's conference with @Humulonimbus! Our vice chairs are @DMart_82 and @KUhokie42! Please follow us for #ORPGRC related updates as we aim for an exciting and diversified ochem conference! #OCHEMRULES!
After a great time at chem summer camp (aka ORP GRC), meeting some awesome chemists like @radscientist_ and @xhimichka, catching up with @OChem_Grenning , @HilinskiGroup and @SieberLabVCU I came home to the best harvest of my “budding” gardening (farming?) career!
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Welcome to another awesome pair of issues from @JOC_OL! This time in #JOrgChem we feature a cool cover of a “blueprint” for synthesizing complex lactones pubs.acs.org/toc/joceah/87/2…. Meanwhile in #OrgLett we present a unique dihomohalogenation methodology pubs.acs.org/toc/orlef7/24/4… 😃
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Happy to share the most recent write-up from my lab on accessing ylides through photo-decarbonylation and trapping them to make a bunch of cycloadducts. Now on @ChemRxiv chemrxiv.org/engage/rss/chem…
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Boskovic lab @chemku reporting in J. Org. Chem. @JOC_OL their efforts to reach complex structures in short order from simple precursors.
Spirocyclic azetidine-lactones in a 7-step process with two key photochemical reactions: aza-Yang cyclization to make azetidinols and Buchner insertion of carbene into an aromatic ring to make lactone and cycloheptatriene. In #JOC from @djavko et al. pubs.acs.org/doi/10.1021/acs…
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Synthesis of Cycloheptatriene-Containing Azetidine Lactones pubs.acs.org/doi/10.1021/acs…
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Spirocyclic azetidine-lactones in a 7-step process with two key photochemical reactions: aza-Yang cyclization to make azetidinols and Buchner insertion of carbene into an aromatic ring to make lactone and cycloheptatriene. In #JOC from @djavko et al. pubs.acs.org/doi/10.1021/acs…
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This project had about 11 crystal structures and hundreds of spectra to assign. This is still a manual labor. We posted .sdf files at our GitHub repository, together with the codes for figures and analyses. Hope you like what we did. Happy Nu Year!
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We collaborated with Elles group to measure the femtosecond events following photon absorption. Protonation of the amine is key to prevent the charge transfer from amine to the excited carbonyl. And we measured the quantum yield for product formation.
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Very excited and proud to share with you the product of our year of hard work: chemrxiv.org/engage/chemrxiv… total synthesis of non-natural molecules.