Scientist, Oncology Bioinformatics at @moderna_tx. PhD in Computational and Systems Biology from @WUSTLdbbs. Genomics 🤘.
Taipei
Joined September 2012
- Tweets2.1K
- Following600
- Followers340
- Likes2.6K
Liang-Bo Wang retweeted
Today Cell, Cancer Cell and Cell Reports Medicine are pleased to publish the 1st wave of Pan-#Cancer multiomics papers looking at over 1000 patients across 10 #tumor types from @theNCI Clinical Proteomic Tumor Analysis Consortium #CPTAC (1/n) @Cancer_Cell @CellRepMed #openaccess
Liang-Bo Wang retweeted
We are excited to announce a collection of new human reference genome sequences that reflect much more global diversity!
nature.com/articles/s41586-0…
Liang-Bo Wang retweeted
webR v0.1.0 has just been released! I'm super excited to see what people create by using webR in their own projects 😃. The docs are at docs.r-wasm.org and I've written an introductory blog post talking more about the kind of things webR can do at tidyverse.org/blog/2023/03/w….
Liang-Bo Wang retweeted
english.cw.com.tw/article/ar…
Thanks to Commonwealth Magazine @CWM_en for publishing a summary version of my article detailing my experience of becoming a Taiwanese citizen as a Taiwan Gold Card holder. Please share it forward to those who may benefit from it. Thank you
Liang-Bo Wang retweeted
Our single-cell MPRA paper is finally out! Super excited about the potential of this technology to study cell-type specific gene regulation 🥰
Out today in @NatureGenet, our group’s single-cell MPRA technology for testing activities of gene regulatory elements in whole tissues.
Congrats to Siqi Zhao and the rest of the crew for their great work!
nature.com/articles/s41588-0…
Liang-Bo Wang retweeted
We are delighted to share our work, now available in
@Nature:
nature.com/articles/s41586-0…
Our scoring system can be accessed here: kinase-library.phosphosite.o…
Coming soon --> the tyrosine kinome and an improved system with many new functionalities & features!
#TheKinaseLibrary #KL
Liang-Bo Wang retweeted
Our paper on insulators is out on Biorxiv! We tested the activity of insulators across thousands of genomic locations to figure out where insulators function. Oh, and I successfully defended today :) biorxiv.org/content/10.1101/…
Liang-Bo Wang retweeted
Finally sharing this collaborative work with my amazing labmates Avi and Siqi! We asked how chromosome position and cellular environments impact gene expression noise by developing a new single-cell method (with a genomicsy name just because) 😉
biorxiv.org/content/10.1101/…
Liang-Bo Wang retweeted
I designed this cover for my PhD thesis using #DALL-E and #StableDiffusion, I'm quite happy with the result!
Took a few steps to combine the strengths of both engines, I found SD: beautiful images, DALLE: gets the story right; look at the steps below: (1/5+2)
Liang-Bo Wang retweeted
After more than two years of working on this project, we are delighted to share our effort in harmonizing the tumor microenvironment (TME) of glioblastoma (GB) at single-cell resolution and providing insights into the tumor architecture (biorxiv.org/cgi/content/shor…).
Details 🧵👇🏼 1/N
Liang-Bo Wang retweeted
‼️ ONLINE NOW @NatureGenet
📰 Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer
🧑🏾🤝🧑🏻 Li Ding @reykajayasinghe @DeNardoLabWUSM and colleagues
⬇️
go.nature.com/3AEvt3n
Liang-Bo Wang retweeted
There are different versions of the human genome annotation but which do you use?
The Matched Annotation from @NCBI and EMBL-EBI (MANE) collaboration is the answer and brings new meaning to the phrase: two heads are better than one.
ebi.ac.uk/about/news/researc…
Liang-Bo Wang retweeted
We have a new version of this preprint! There are 2 key changes - we now show that scMPRA works in mouse retina (!), and we finally implemented the second U6 transcript to detect unexpressed promoters. Siqi worked really hard on this so please check it out 🙂
Check out the latest preprint from our lab by my dear friend Siqi :) He developed a method to perform MPRAs in single cells and show that it can be used to detect cell-type specific regulation and cell-to-cell variability in cis-regulatory elements!
biorxiv.org/content/10.1101/…
Liang-Bo Wang retweeted
Asked in email today about using residuals of one models as data in another. My book (image below) says never to do this, but it's common in some fields. But my book doesn't say much else. Hence the question from a reader.
Short paper on the topic: doi.org/10.1046/j.1365-2656.…
Liang-Bo Wang retweeted
A Draft Human Pangenome Reference biorxiv.org/cgi/content/shor… #bioRxiv
Liang-Bo Wang retweeted
Did you know that you can query any parquet or csv file on all of GitHub just by going to the @DuckDB WASM shell website?
shell.duckdb.org/
Liang-Bo Wang retweeted
KeeWeb is looking for a maintainer: github.com/keeweb/keeweb/iss…
Liang-Bo Wang retweeted
Created with DALL·E 2 by @OpenAI
📝 "An IT-guy trying to fix hardware of a PC tower is being tangled by the PC cables like Laokoon. Marble, copy after Hellenistic original from ca. 200 BC. Found in the Baths of Trajan, 1506."
🔎 He just can't
#DALLE // #dalle2 // #DALLEmerz
Liang-Bo Wang retweeted
Ppl are on twitter for many reasons. I'm here to chew bubblegum & teach scientific inference. And I'm all out of gum. Engage yourself with 20+ hours of free lectures on causal inference and Bayesian data analysis. This isn't an ordinary statistics course. github.com/rmcelreath/stat_r…