Scientist. Avid book clubber. Overly enthusiastic dancer. Postdoc with @Marston_lab @WTCell. Personal account.
Edinburgh, Scotland
Joined April 2010
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Lori Koch retweeted
YeastMine is closing July 15 due to ongoing funding cuts. For more info: community.alliancegenome.org… #yeast
Lori Koch retweeted
Big thanks to all @DKW_2024 participants for excellent science, engaging conversations, and mountain excursions! We hope to see everyone in Oxford in 2027. Thanks also to our generous sponsors @EMBOevents @Co_Biologists @eLife @Chromosoma_EB @snsf_ch @UNIGEnews @EMBO
Check out our shiny app to explore meiotic phosphorylation!! meiphosprot.bio.ed.ac.uk/
#meiosis #phosphorylation #proteomics #yeast #meiosis4eva
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Lori Koch retweeted
Prof Adele Marston is our 2024 Mary Lyon Medal winner and is giving her talk tonight at the “Developmental Genetics” conference. Congratulations @Marston_lab! #BSDBGenSoc2024
Lori Koch retweeted
Happy to share our new preprint, the work of the brilliant Menglu (Lily) Wang . Thanks to our wonderful MS collaborators @RappsilberLab @jurirappsilber Christos & Juan.
Molecular basis for condensin enrichment at pericentromeres biorxiv.org/content/10.1101/…
Happy to see our work out at @embojournal !! Special thanks to the amazing Adele @Marston_lab and everyone who helped with this project. 😄👩🔬🧪⏲️
Phosphoproteomics reveal pervasive rewiring of Cdk1 and Polo kinase phosphorylations during yeast meiosis, ensuring the occurrence of two successive divisions without intervening S-phase
Lori Koch, Adele Marston et al
@lbkoch9 @Marston_lab @WTCell
embopress.org/doi/full/10.10…
Lori Koch retweeted
Happy to see this published finally! Congratulations @BMihalas and all authors! Thanks to the constructive reviewers and @AnneKnowlton1 and to the couples who donated oocytes.
Age-dependent loss of cohesion protection in human oocytes sciencedirect.com/science/ar…
Congrats @LisaKursel !!
I had a lot of fun working on this story and I'm pleased to see it now published. A pleasure as always to work with @TheRogLab and congrats to undergrad Jesus on his first publication 🎉
See quoted tweet for a link to the paper and a taste of our findings 🙂
Congratulations Adele @Marston_lab !! 👩🔬🧪🌟
🏅Thrilled to announce that Prof Adele Marston @Marston_lab, has been awarded the 2024 Mary Lyon Medal. This award recognises outstanding research in genetics to scientists who are in the middle of their research career.
@uniofedinburgh
genetics.org.uk/8-november-2…
Happy to share our preprint, check it out here:
Rewiring of the phosphoproteome executes two meiotic divisions biorxiv.org/content/10.1101/…
Check out our work on phosphorylation dynamics during the meiotic divisions 👩🔬🧪
Delighted to share Lori Koch’s @lbkoch9 tour-de-force phosphoproteomics of the meiotic divisions. She reports dynamics for thousands of phosphosites and shows that Spo13/Meikin directs Polo kinase to substrates with a novel motif. biorxiv.org/content/10.1101/…
Very proud of my partner Nitobe, who is a formidable biochemist!! 🤓🧑🔬🧪
sciencedirect.com/science/ar…
Lori Koch retweeted
A £9 million grant from @wellcometrust will fund a new Discovery Research Platform for Hidden Cell Biology
It will reveal deep insights into the inner world of cells, shedding new light on diseases and antimicrobial drug resistance.
➡️ edin.ac/3NDKsl6
Lori Koch retweeted
Great first day at British Meiosis Meeting in Edinburgh, excellent talks from Luz Maria Lopez Ruiz @Piotraz1 @dluzewskajulia @ChrisMorgan555 @BioJNO Arne Klungland @lbkoch9 @hdlopez80 @JoshPPrince @weir_science. Looking forward to the poster session this evening. #BMM2023
Lori Koch retweeted
I'm incredibly proud to post this work from my postdoc in Edinburgh @Marston_lab. Please check out our preprint. I hope you like it as much as we do 😁
biorxiv.org/content/10.1101/…
Lori Koch retweeted
Out on bioRxiv! Our study showing how a kinase critical to cell cycle control, CDK1, switches consensus sequence to phosphorylate non-proline directed sites in human cells. biorxiv.org/content/10.1101/…
Lori Koch retweeted
I’m so excited to share our reconstitution system where we saw individual yeast kinetochores on yeast microtubules. But that’s not all, these kinetochores MOVE! We found the kinesin-8, Kip3, moves kinetochores towards the plus-end of the microtubule biorxiv.org/content/10.1101/…
Lori Koch retweeted
Excited this work is out-fantastic collaboration with @glennis_logsdon to identify transcripts at and around yeast centromeres:
transcriptional roadblock protects yeast centromeres academic.oup.com/nar/advance…
Lori Koch retweeted
Excited to see this out in @eLife . Many congratulations to Rachael, Lucia and Dan. Thanks to the reviewers and editors for a positive experience. Chromatin loops are really important for meiosis!
doi.org/10.7554/eLife.74447 @eLife
Many thanks to my co-authors and especially to @SueBiggins and Chip for their excellent mentorship!
Work from the @SueBiggins and Asbury labs shows that Mps1 phosphorylates the Ndc80 kinetochore protein to regulate the strength of #kinetochore-#microtubule attachments. This phosphorylation contributes to mitotic error correction in cells. bit.ly/2XfUl0y
#CellDivision
