An itinerant mind with a professional interest in health and a vast curiosity for anything else. Views here are my own.

KL
Joined July 2009
Mind boggling display of creativity and joy
Being an exceptionally talented musician is one thing. But to stand before such high-caliber fellow musicians, a large audience, and cameras—all while remaining composed, communicating skillfully and effectively, showing genuine enjoyment, and staying focused on the creative process—that is what truly amazes me.
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I am a member of the Norwegian Nobel Committee. There are five of us. Five people, appointed by a parliament most of the planet could not find on a map, who decide, once a year, which human being the world has agreed to call good. I know. I know. I think about it on the tram. We meet in a building on Henrik Ibsens gate, a street named after a man who wrote almost exclusively about people discovering they are frauds, which nobody on the committee finds funny except me. There is a room with a long table and the portraits of the dead laureates looking down, Mandela, the Dalai Lama, a great many earnest men in spectacles, and one portrait we do not discuss, which is Kissinger, 1973, awarded while the bombs were still falling, after which two of our predecessors resigned and the satirist Tom Lehrer said political satire was now obsolete. We keep him on the wall. A reminder. Every family has the uncle. It is October in Oslo, which means the sun gives up around four in the afternoon like a civil servant, and it rains the particular Norwegian rain that isn’t quite falling, just hanging there, judging you. I arrive with wet shoes. I always arrive with wet shoes. There is coffee, because this is Norway and there is always coffee, we drink more of it per person than almost anyone alive, and someone’s wife has sent kanelboller, the cinnamon buns, and we sit, five Norwegians, damp, caffeinated, sugared, and we decide the moral standing of the entire species. Let me tell you how it actually works, because the world imagines a cathedral and it is, I promise you, a book club with a mandate. 287 nominations this year. 208 people, 79 organizations. Anyone can nominate, that’s the secret nobody understands: a professor, a parliamentarian, a former laureate, so the “nominee” list is meaningless, it’s a suggestion box, and every autumn some congressman nominates his own golden retriever and the press writes “SHORTLISTED.” Nobody is shortlisted. There is no short list the public ever sees. There is us, and the coffee, and the rain, and the portraits, and a Norwegian stubbornness that is older than the prize itself. We read reports. The institute’s advisers write them, thick dull documents, and we argue. Our chairman told the BBC once that in the final meeting “there is a high temperature.” High temperature, for a Norwegian, means someone slightly raised an eyebrow and then apologized for it. We don’t do high temperature. We do a long silence, and then Kristin says “well,” and everyone knows exactly what “well” meant, and it’s settled. That’s our shouting. “Well.” You’d have to be raised here to hear the violence in it. Now. This year. I will not say the name, because we never say the name, but you know the name. A certain head of state wanted this prize the way a child wants a thing in a shop window, which is to say loudly, and in public, and with the full belief that wanting it was itself the argument. He said he deserved it. He said he’d ended eight wars, a number that grew most times he said it, like a fish. He had other heads of state phone us. Israel’s prime minister posted it on the internet, “Give him the Nobel.” The leaders of Cambodia and Pakistan announced they’d nominated him, as though announcing it were part of it, as though we tally mentions. A man flew around the globe collecting endorsements for a Norwegian committee the way you’d collect signatures for a petition to the council about a noisy dog. And here, uff da, is the detail I treasure, the one that makes me smile into my coffee. The nomination deadline is the 31st of January. He took office on the 20th. So for all the phone calls, all the posts, all the gilded lobbying, the only nominations that could possibly count for this year’s prize were filed in the first eleven days of his term, before he had, by his own arithmetic, ended a single one of the eight wars. He campaigned all year for a prize whose window had shut while he was still hanging up his coat. We didn’t have to reject him. The calendar did. We just watched. Norwegians are very good at watching. We have long winters. People think we sit there weighing his deeds. We don’t. That’s the thing I can’t make the world understand. We’re not grading his homework. We don’t owe anyone the prize for a ceasefire, however real, however loud the announcement. “He made peace” is not a sentence that ends in a medal, the way he believes it does, the way he believes every good thing ends in his name on it. The will of a dead Swede says the prize goes to whoever did the most for fraternity between nations. A dead Swede, I should add, who made his entire fortune inventing dynamite and selling arms, and spent his last years horrified at his own obituary, which called him a merchant of death, and so bought his way to immortality as a man of peace. The whole prize is one guilty arms dealer’s attempt to launder his name. We are, all of us, administering a dead man’s public relations. I find this clarifying. It keeps me humble. It should keep everyone humble, and it keeps, by my count, no one humble at all. So who did we give it to? An eighty-five-year-old woman. A judge. Born in Durban, under apartheid, granddaughter of a Tamil man who came to South Africa as indentured labor, a bus driver’s daughter from the poor Indian quarter, who became the first non-white woman to run a law practice in her province, who defended Mandela’s people when defending them was dangerous, who sat on the Rwanda tribunal and the court at the Hague, and who, at eighty-five, is right now a judge weighing whether a genocide is a genocide. When we told the world, our chairman said the rule of law “underpins the system we have set up to ensure peace,” and that “peace requires justice.” She wasn’t even in Oslo. She was in Nuremberg. In courtroom 600. The actual room where they tried the Nazis. You cannot stage that. God staged that, and God, it turns out, is a better satirist than any of us. She did not phone us. She did not post. No prime minister demanded it for her on the internet. She had, as far as our deliberations are concerned, the one qualification the loud man could never manufacture, which is that she wanted the work and not the medal. The medal finds those people. It flees the ones who chase it. This is not a rule we wrote. It’s just the only pattern the hundred-odd years of our mistakes has ever shown. The reaction from across the ocean was immediate. His spokesman posted that we “place politics over peace.” Ja. Perhaps. We’re five damp pensioners in a rainy city; of course it’s political, it was always political, it was political when we gave it to a sitting American president nine months into his first term for the promise of things he had not yet done, and we have been quietly embarrassed about that one for fifteen years, so believe me, we had a particular reason this year to prefer a woman with fifty years of verdicts behind her over a man with eight wars in front of him and a deadline already behind him. Here is what he will never understand, the thing I’d tell him on the tram if he ever took one. We are the one prize he cannot buy, cannot post his way to, cannot have a friendly dictator phone in for him. Not because we’re incorruptible, nei, we’re as vain and wrong and human as the portraits on our wall. But because the entire point of the thing, the only power a small cold country’s book club has ever held, is that it goes to the person not performing the wanting. The moment you demand it, you’ve proven you don’t understand what it’s for, and proving that is itself the disqualification. He ran the most expensive campaign in the history of the prize and the campaign was the reason. He was never losing to Navi Pillay. He was losing to the concept. It’s dark now. Four o’clock dark. The buns are gone. Kristin said “well” an hour ago and we all went home. I’m on the tram with my wet shoes, and somewhere across the water a very powerful man is explaining to a camera that the prize is rigged, that we’re corrupt, that he’ll win it next year, and he genuinely might, we’re only five idiots and we’ve been wrong before, Kissinger is still on the wall. But not this year. This year an old woman in Nuremberg, in the room where the law once stared down the exact kind of man who thinks wanting a thing loudly enough should make it his, got a phone call she didn’t ask for. That’s the job. We don’t reward the man who ends the war and announces it. We reward the woman who spent fifty years deciding what a war was. He’ll never see the difference. That’s rather the whole point of him. Takk for i dag. I have to change trams.
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Spare a thought for folks who depend on outdoor activities for a living like hiking guides, tour guides etc. I can’t imagine times are good for them. Does anyone know if they need help?
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Untuk makluman para siswazah perubatan sekalian 😂
Physician compensation versus lifestyle balance (a composite index by Marit that accounts for weekly hours, long shift or after-hours work, call burden, and vacation weeks) by major specialty
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Nadiah Wan retweeted
In an age dominated by technology, in which efficiency and profit often take precedence, it is so important that we continue to cultivate a spirit of contemplation and allow time and space for beauty. Such an attitude will greatly help humanity, especially young people, to discover the ability of art to uplift and reveal the depths of the human spirit and our openness to the divine. Contemplation presents a marvelous opportunity to encounter the God who is Beauty.
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Actually banking convenience is the one thing I miss about home when travelling to the west.
几年前来马来西亚,我换了一叠现金塞行李箱。 到今天,那叠钱还在行李箱里。 国内人对这边最大的误解,可能就是支付 👇 出发前朋友认真问我:那边有网吗?要不要多带点现金? 现实是:路边卖椰浆饭的阿姨都有二维码。过路费、停车、水电费、转账,一个 Touch 'n Go 全包。 担心安全? Touch 'n Go 早期是蚂蚁金服扶持起来的,底子就是支付宝那套。 而且支付宝微信本身也接了一大批商家,不开本地账户也能过日子。 说白了是信息差。 国内对东南亚的印象还是椰子树加摩天大楼的明信片,这边这几年悄悄把数字化补齐了。 只是没人出来说。 所以想来这边的:现金别操心,下飞机打开支付宝就能吃饭。 你对马来西亚最大的误解是什么?评论区说说
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Brain-Eye complex. Beyond cool. congrats!
BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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Nadiah Wan retweeted
I first read @yuxin_gao's essays when I was posted in Beijing — almost 15 years ago at this point. She has always been one of the most thoughtful writers on Chinese society. This piece is not different: nytimes.com/2026/10/02/opini…
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Nadiah Wan retweeted
I've coached over 30 Olympic gold medals. I've worked with some of the greatest athletes in history. Here are the lessons I wish more people understood:🧵
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Si es de las mujeres que cada vez que hacía un comentario sobre algún dolor que pudiera presentar su cuerpo, la respuesta automática del entorno era “todo es mental”, preste atención porque la ciencia acaba de derrumbar un mito de la medicina que acompañó a las mujeres durante décadas. La revista Science, publicó el pasado 1 de octubre una edición especial dedicada a la Salud de las Mujeres (Women’s Health), que estuvo a cargo de cuatro investigadoras: Yevgeniya Nusinovich, Sacha Vignieri, Joana Osório y Sarah Ross quienes tenían el propósito claro de su investigación: exponer públicamente la brecha histórica de género en los ensayos clínicos y la medicina en general. Durante décadas la academia de medicina avaló la teoría de que las mujeres tenían una menor tolerancia al dolor que los hombres. La realidad es que las mujeres poseen mecanismos biológicos, hormonales y neuroinmunes completamente distintos a los de los caballeros, como se explicó en el artículo Sex-specific mechanisms of chronic pain, que forma parte de la edición especial de la revista científica antes mencionada. La investigación determinó: 1.- Existencia de un dolor somático y un dolor visceral. Los dolores somáticos se exteriorizan en los tejidos externos, músculos y articulaciones. Migrañas, fibromialgia y osteoartritis (más frecuente en las mujeres después de la menopausia que en los hombres al llegar a la andropausia). En cuanto al dolor visceral, se ubica en el síndrome de intestino irritable, dolor de vejiga, órganos internos y sobre todo en la zona pélvica y abdominal en la etapa reproductiva de la mujer. 2.- La culpa del dolor en las mujeres no es exclusiva de la ausencia de estrógenos, la prolactina también tiene su cuota, esta hormona segregada por la glándula pituitaria que al tener una mayor expresión de este gen, sensibiliza las neuronas sensoriales y dispara su excitabilidad y potencia el dolor mediado por el péptido relacionado con el gen de la calcitonina (CGRP), una molécula clave en los ataques de migraña. 3.- Existen diferencias en la forma en las cuales el sistema inmunitario le habla a la neuronas de un hombre o una mujer. En las mujeres, una inflamación intestinal previa puede dejar una disbiosis (alteración microbiana) persistente que perpetúa el dolor crónico. En modelos experimentales, este dolor visceral se pudo transferir a otros sujetos mediante trasplante de microbiota fecal. En el caso de las articulaciones de las mujeres se observa una mayor concentración de quimiocinas inflamatorias (como CCL2 e IL-8) en el líquido sinovial. Esto atrae una infiltración de macrófagos sensiblemente superior a la que se registra en los hombres. 4.- Finalmente, llegamos al cerebro. A nivel periférico los nociceptores (neuronas encargadas de detectar el dolor) expresaron genes completamente diferentes entre hombres y mujeres. La amígdala contribuye a fijar una hipersensibilidad visceral a largo plazo que se activa con el estrés. Estos resultados reveladores trascienden el mero estudio sobre el dolor en las mujeres, dentro de la investigación fue decisivo realizar una advertencia, la inmensa mayoría de los datos genéticos, clínicos y biomédicos corresponden a mujeres de origen europeo. Es urgente que los ensayos incluyan a mujeres de todos los orígenes étnicos y genéticos para que la medicina personalizada sea real. La industria farmacéutica tiene una deuda pero también una oportunidad a partir de esta investigación. Utilizar los resultados para diseñar analgésicos que tengan en cuenta el perfil hormonal, neuroinmune y genérico de las mujeres. Si el tema le apasiona le recomiendo la lectura de esta edición especial de la Revista Science dedica en exclusiva a la salud de la mujer. #CienciaParaLaVida #SaludDeLasMujeres #DolorCrónico #Neurociencia
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Required reading for every female out there
In the new @ScienceMagazine special issue on women's health, a 5★ review of menopause hormone therapy to promote healthy aging science.org/doi/10.1126/scie…
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Dammit hubs scored one question more and got 149 instead of my 144. Fun though!
This one was fun. Because it's adaptive, most of the test is right at your level of ability, so it's neither boring nor overly challe ging (though I will say that a few of the hardest ones I was entirely guessing) taketest.xyz/vocab-cat
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Bookmarking to watch
בגלל העניין והחשיבות הציבורית אני ורחלי החלטנו ביחד עם הגרדיאן שהסרט נז״א יהיה נגיש באינטרנט בחינם, ללא הגבלת זמן, כדי שכל אדם יוכל לצפות בו ובעדויות החיילים. זה יקרה בעוד כמה שבועות, בנובמבר, במועד הכי מוקדם שהצלחנו לקבוע. עד אז פנינו לבתי קולנוע בישראל והצענו להם את הסרט ללא עלות, בתקווה שיוקרן בארץ כבר עכשיו, במקביל להפצתו בבתי קולנוע בעולם. הצגתו תהיה החלטה אמיצה אל מול אלימות גדולה שמכוונת להסתרתו. אני יודע שיש ביקוש אדיר לצפות בסרט ואני מקווה שבאופן הזה כולם בקרוב יוכלו לראות אותו: בין אם בבתי הקולנוע ובין אם באינטרנט בעוד כמה שבועות. הרבה דברים לא נכונים נאמרו עלינו ועל הסרט בשבוע החולף. הסרט מבוסס על תחקיר עיתונאי מקיף של שלוש שנים והפרטים בו מאומתים ומוצלבים. הוא ידבר בעד עצמו והאמת סופה להתבהר. עשינו את הסרט כדי לעורר דיון ציבורי לגבי המעשים של הממשלה בעזה, ההרג של יותר מ73,000 בני אדם, רובם אזרחים, הנרמול של מלחמת השמדה, של התפיסה ש״אין בלתי מעורבים״. עשרים וארבעה חיילים וחיילות עשו צעד ודיברו מול מצלמה על מה שחברה שלמה לא רוצה לדבר עליו. ההכרה בזוועות בעזה לא מפחיתה לרגע מהטבח הנפשע של השבעה באוקטובר, שחמאס אחראי עליו, שחיילים מדברים עליו בסרט, ושאין לו שום הצדקה. להפך. הרי ההתעלמות ממה שקורה בעזה היא מהגורמים שסללו את הדרך לשבת הנוראה ההיא. וההתעלמות הזו נמשכת. עיתונות היא לא בגידה. ביקורת היא לא בגידה. זו חובה של כל אזרח שממשלתו מבצעת פשעים לדעת ושל כל חייל שהיה עד להם לספר. מסתובבים כאן אלפי חיילים כאלה, שיצפו בסרט ויזהו את מה שמתואר בו באופן אישי: את ההרג של אנשים לא חמושים שחוצים קו מדומיין, את אישורי הנז״א במאות, את התקיפות המערכתיות בבתי משפחות, את השריפה וההשמדה הפיזית של עזה, רצח וירי על אנשים רעבים במרכזי מזון ופשעים נוספים שאין להם הצדקה. גם אם זה מפחיד, זו חובתכם למצוא את הדרך להעיד על מה שראיתם. יגידו לכם שכדאי להסתיר את האמת למען הסברה בחו״ל, אבל זה קשקוש. שם יודעים כבר הכל. פשעים לא מסבירים אלא עוצרים. הסתרת האמת קודם כל מרעילה את החברה שלנו ומעל הכל מאפשרת לפגיעה בבני אדם בעזה להימשך. ובנימה אישית: אני כותב על מדיניות האש של הצבא בעזה בעברית ב״שיחה מקומית״ כבר שלוש שנים. התחקירים זכו להתעלמות בישראל. עכשיו בפעם הראשונה משהו נסדק במסך ההתעלמות - וזה דבר חיובי. זה דבר בריא. כן, זה מגיע עם מחיר אישי גדול. היה שבוע קשה. אבל בתוכו גם יש המון תמיכה, והרבה נדיבות. מה שבטוח: האיומים לא יעזרו. זה לא מרתיע אותנו. אני ורחלי נחזור לארץ ונמשיך להיאבק על עתיד המקום הזה ביחד עם שותפים רבים.
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Congrats!!!
Permata Seni Koir (PSK) mencipta sejarah apabila muncul juara keseluruhan 3rd Internationales Chorfest di Magdeburg, Jerman, selepas mengumpul 29 daripada 30 mata. Pertandingan yang berlangsung dari 16 hingga 20 September lalu itu menyaksikan PSK bersaing dengan kumpulan yang terdiri daripada peserta lebih berusia dan berpengalaman. #BuletinTV3 #PSK #Jerman #PermataSeniKoir
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Nadiah Wan retweeted
In light of the progress in mathematics, we at Edison Scientific and FutureHouse have assembled a set of Millennium Problems for Biology. They are chosen to be very hard to solve but very easy to validate in a simple laboratory environment. Any of these, if solved, would mark a major advance in biotechnology, and most of them would contribute materially towards curing disease. These are, in some sense, the “last reasonable eval” for AI in biology. This was work primarily by @MichaelaThinks and myself, with contributions from many others. Short descriptions below. The full descriptions of the problems with acceptance criteria are at the Bio Millennium Problems website, linked in the next post. Share more if you have ideas. If they meet our criteria, we’ll add them to our list (with attribution and permission).
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Today’s 2026 Tsinghua PBCSF Chief Economists Forum featured Justin Yifu Lin, Yu Yongding, Yao Yang, Li Xunlei, and Ju Jiandong. I’ve prepared a transcript of their latest views on China’s macroeconomic and trade issues. fredgao.com/p/chinas-top-eco…
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If so it begs the question of how equipped our schools are to detect students with serious mental illness.
🚨 JUST IN: The Shah Alam High Court has acquitted the male student accused of killing his female schoolmate at a school in Bandar Utama last year. The court had accepted evidence from a court-appointed psychiatrist who confirmed that the teenager had serious schizophrenia and was of unsound mind at the time of the incident. 🧵1
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And what is our MOE doing I wonder
MIT published a brutally honest report on what AI is doing to students. A committee of professors and students spent five months studying how AI changed learning on campus, and the findings read like a warning to every university on the planet. Study groups are disappearing. Office hours are emptying out. Problem sets and take-home exams no longer prove anything, because AI can produce credible solutions to almost any written assignment in the undergraduate curriculum. Students who lean on chatbots lose mastery and confidence, and some slip into what the report calls cognitive surrender, reaching for AI at the first hint of struggle. The numbers are rough. 46 percent of surveyed MIT undergrads use LLMs daily. 90 percent worry about their own overreliance. Undergrads who feel AI makes them replaceable now outnumber those who feel it makes them capable. The committee's answer surprised me. They refused to fight AI with surveillance. The report calls AI detectors unreliable, says lockdown browsers feel like spying, and warns that policing students builds a classroom atmosphere of mutual distrust. Instead, MIT wants to rebuild education around the things AI can't replace. That means oral exams, semester portfolios, in-person project work, and a required social component in every subject. The report even floats the idea of rethinking grades entirely, since without a GPA to optimize, much of the incentive to cheat with AI evaporates. The committee warns professors against replacing undergrad research assistants with AI agents just because they're cheaper, because a university exists to grow people, not output. The most famous tech school on earth admitted the machines broke its way of teaching. Its answer is more humans, not more software.
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Why is 'lb' the abbreviation for 'pound'?
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