@lab_wein

We study bone, the best tissue

 Boston, MA
scholar.harvard.edu/wein
Joined September 2021
  • Tweets84
  • Following209
  • Followers272
25Media
steppingstrong.bwh.harvard.e…

Funded Projects | The Gillian Reny Stepping Strong Center for Trauma Innovation

Explore the groundbreaking initiatives that The Gillian Reny Stepping Strong Center for Trauma Innovation has supported.

steppingstrong.bwh.harvard.edu
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Happy to share great work from @CourtneyMMazur - functional genomics to study osteocyte differentiation Genome-wide CRISPR interference screen identifies Clip2 as a novel regulator of osteocyte maturation and morphology biorxiv.org/content/10.1101/…

Genome-wide CRISPR interference screen identifies Clip2 as a novel regulator of osteocyte maturat...

Osteocytes play critical roles in bone, making them attractive targets for therapeutics to improve bone mass and strength. The genes driving osteocyte maturation and function are not fully understo...

biorxiv.org
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Great eats and science at #ASBMR2025 Thanks ⁦@LilianIPlotkin⁩ ⁦@edguo84⁩ ⁦@JWestendorfPhD⁩ for such a fantastic meeting
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What causes delirium? Maybe defects in glymphatic flow? More insights into pathophysiology from patients from Pathways @mghmedres @MGHMedicine The Neurobiology of Delirium in a Septic Elderly Hospitalized Patient advances.massgeneral.org/res… via @MassGeneralNews

The Neurobiology of Delirium in a Septic Elderly Hospitalized Patient

A 78-year-old woman with a history of poorly controlled type 2 diabetes mellitus and diabetic kidney disease presented to Massachusetts General Hospital for acute physical and mental decline.

advances.massgeneral.org
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More things that make you go hmm from the Pathways consult service... Why does GCA affect different vessels? @mghmedres @MGHMedicine @MGH_RI Pathways Case Report: A Case of Extracranial Giant Cell Arteritis advances.massgeneral.org/res… via @MassGeneralNews

Pathways Case Report: A Case of Extracranial Giant Cell Arteritis

A 90-year-old woman presented to the hospital with 3-4 weeks of back pain radiating to her chest and abdomen without additional constitutional symptoms.

advances.massgeneral.org
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Love this thoughtful discussion about common and rare causes of statin myopathies @MichaelNTrinh @mghmedres @MGHMedicine Pathways Case Report: Anti-HMGCR Statin-associated Myopathy advances.massgeneral.org/car… via @MassGeneralNews

Pathways Case Report: Anti-HMGCR Statin-associated Myopathy

A 69-year-old man with a past medical history of a non-ST-segment elevation myocardial infarction (NSTEMI) was admitted to Mass General with back pain radiating to the shoulders and hip.

advances.massgeneral.org
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Happy Friday- it's preprint time... Crosstalk between mechanical signals and cAMP @FayPapaioanMD biorxiv.org/content/10.1101/… SIKs in alveolar bone from Nicha T @OnoNoriaki biorxiv.org/content/10.1101/… Osteocyte dendrite mRNA trafficking @CourtneyMMazur @JMTali biorxiv.org/content/10.1101/…
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Congrats to Bill on ‘cutting the interim’ as much-deserved official ⁦@mghmedres⁩ director (w John Potts always looking over the action…)
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Congrats ⁦@CourtneyMMazur⁩ - #ASBMR2024 young investigator!
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Fun collaboration with @wm_oldham @chivukula_raghu: from a Pathways patient to a novel NOS3 mutation. Amazing what we find when we let our patients teach us... @mghmedres @MGH_RI ahajournals.org/doi/10.1161/…

Exercise Intolerance and Low Cardiac Filling Pressures in a Woman With a Novel eNOS Mutation |...

ahajournals.org
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Inspiring to learn from @RWalensky at our @mghmedres @MGHMedicine physician/scientist retreat
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Summer lab outing! great games @l99gaming and food @JABeerHall
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Surprise! Wonderful to celebrate @SeannaYoon's imminent new arrival this morning. 9am is NOT too early for dessert... @MGH_RI @CSR_MGH @goChoate
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Sad for us, but lucky for @UNCmdphd that our all-star research technician Nena K is leaving @MGH_RI @CSR_MGH to be a tar heel. Can't wait to follow all your success in years to come!
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Treatments emerge for rare ‘catastrophic’ bone growth disease | Science | AAAS science.org/content/article/…

Treatments emerge for rare ‘catastrophic’ bone growth disease

Five drugs are now approved or in trials for genetic condition that triggers misplaced bone growth

science.org
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Great speaking with @chrisworsham about asking questions through Pathways @mghmedres @MGHMedicine. Love this newsletter @AnupamBJena How can we teach doctors what they don't know? open.substack.com/pub/random…
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We are thrilled that Henry M. Kronenberg, MD of the Endocrine Unit at the MGH has been elected member of the National Academy of Sciences! Warmest congratulations, Hank!#NASmembers@ @MGHMedicine
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Big congrats to Nicha who successfully defended her @dental_harvard DMSc thesis today. And THANKS for teaching us all to love alveolar bone!
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Congrats ⁦@SeannaYoon⁩ - 2024 AIMM young investigator!!!
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A chronic bone disease won't stop Emily Roach on Marathon Monday bostonglobe.com/2024/04/07/m… via @BostonGlobe

‘It’s going to feel like such a triumph’: Local runner overcomes rare bone disease to take on the...

Emily Roach was diagnosed with fibrous dysplasia, a disease that causes weak spots in her bones, when she was four years old. Now 26, she's soon to cross the historic finish line.

bostonglobe.com
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