Rahul kumar (@kumar99_rahul) profile picture

Rahul kumar

@kumar99_rahul

Research Scholar , NCBS-TIFR

 Bengaluru, India
Joined February 2012
  • Tweets56
  • Following2.5K
  • Followers110
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Photo by Rahul kumar (@kumar99_rahul)
Preprint alert 🚨 We develop a computational pipeline, CSI-TME, to infer interactions in the TME of IDH-Mut glioma by using bulk RNA-seq data and typically requires scRNA-seq data. @NCIDataSci @NCIKenAldape @NCIEytanRuppin @hannenhalli
bioRxiv Cancer Bio (@biorxiv_cancer) profile picturebioRxiv Cancer Bio@biorxiv_cancer4 Nov 2024
Identifying Prognostic Cell State Interactions in the TumorMicroenvironment of IDH-Mutant Gliomas Using CSI-TME biorxiv.org/cgi/content/shor… #biorxiv_cancer
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Thrilled to share my new illustrations, together with @Rupsykhurana, on recent findings from our lab @r_sabarinathan @NCBS_Bangalore published in @MolOncology buff.ly/3GD9agz #scicomm #VisualArt #cancer #HPV Check out this news page for more news.ncbs.res.in/research-ex…
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Excited to share that Anurag's work on cis-regulatory effect of #HPV integrations in #cervicalcancer is now published buff.ly/3GD9agz in @MolOncology. Thanks to the fantastic collaborators @kaiwalya17 @DimpleNotani @NCBS_Bangalore and @d_tavernari @CirielloLab @dbc_unil!!
Molecular Oncology (@MolOncology) profile pictureMolecular Oncology@MolOncology12 Dec 2023
🆕Don't miss this - now online 📰Cis-regulatory effect of HPV integration is constrained by host chromatin architecture in cervical cancers 🔗buff.ly/3GD9agz #Virology #Epigenetics #Chromatin #CervicalCancer
Image from Molecular Oncology (@MolOncology)
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The next talk at #EMBLCanGen @EMBLEvents is being given by @r_sabarinathan @NCBS_Bangalore, who is telling us about the impact of chromatin architecture on somatic mutational processes
Image from Daniela Robles @daniela-oaks.bsky.social (@daniela_oaks)
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Excited to share the work of @faseelaee from the lab, jointly with @DimpleNotani, @NCBS_Bangalore uncovering the molecular mechanism underlying increased somatic mutations at CTCF/Cohesin-binding sites (CBSs) at chromatin-loop anchors and TAD boundaries in cancer. See thread 👇
bioRxiv (@biorxivpreprint) profile picturebioRxiv@biorxivpreprint27 Oct 2023
Replication stress underlies genomic instability at CTCF/cohesin-binding sites in cancer biorxiv.org/cgi/content/shor… #bioRxiv
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Very excited to share that my manuscript with @r_sabarinathan and @DimpleNotani on the mechanism behind increased mutations at CTCF/cohesin binding sites in cancers is now online on @biorxivpreprint @biorxiv_genomic Please give it a read here: biorxiv.org/content/10.1101/…
Replication stress underlies genomic instability at CTCF/cohesin-binding sites in cancer

Replication stress underlies genomic instability at CTCF/cohesin-binding sites in cancer

CCCTC-binding factor (CTCF) and cohesin play a significant role in the formation of chromatin loops and topologically associating domains (TADs), which influence gene expression and DNA replication....

biorxiv.org
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Replying to @NCBS_Bangalore @r_sabarinathan
The dedicated team behind this successful workshop @skouped, @nivedhya_venas , @MuskanGupta_6, @kumar99_rahul,  @mkjolly15, @SimonGrundSorensen, @naveen_luke @BratatiKahali, @shramdas, @karthikraman, @Sarthak_Sahoo_, Anurag, Faseela and Awadhesh along with the wonderful students.
Image from National Centre for Biological Sciences (@NCBS_Bangalore)
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Exciting to share this news article @IndiaBioscience about our recent work on prognostic association of immunoproteasome expression to immune checkpoint blockade therapies in solid tumors @MolOncology. Thanks @PurvaVariyar for this nice work and @RohanKhadilkarr for your views!!
IndiaBioscience.org (@IndiaBioscience) profile pictureIndiaBioscience.org
@IndiaBioscience9 Jun 2023
New research from @NCBS_Bangalore & @iiscbangalore! 🧪🔬 They attempt to understand specific #biomarkers and the immune environment to predict how patients will respond to immune checkpoint blockade (ICB) therapies for solid tumors 🔍 Read 👇 buff.ly/45NsfrV #Cancer
Image from IndiaBioscience.org (@IndiaBioscience)
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Winning the evolutionary gamble - bacteria know a trick, do you? Follow the link! news.ncbs.res.in/research-ex… Congratulations @DeepaAgashe, Lindi, @MrudulaSane, and others on this beautiful work. Thanks, @JoannaMasel for sharing your thoughts!
Image from Nivedita Mukherjee (@niveditamj)
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⚠️In case you missed it! Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment 👉buff.ly/42RyKrH #Immunoproteasome #Biomarker #SolidTumours #ImmuneMicroenvironment #MELNM @DynamicsLiving
Image from Molecular Oncology (@MolOncology)
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Our recent work exploring immunoproteasome (IP) expression in solid tumours and its impact on the patients' survival and response to immune checkpoint blockade (ICB) therapies is now published in @MolOncology doi.org/10.1002/1878-0261.13…. Congratulations @kumar99_rahul and Bhavya!!
Image from Sabarinathan Radhakrishnan (@r_sabarinathan)
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New preprint from the lab! Cis-regulatory effect of HPV integration in cervical tumours. Work lead by Anurag Kumar Singh in collaboration with @kaiwalya17 @DimpleNotani @d_tavernari @CirielloLab. Tweetorial👇biorxiv.org/content/10.1101/…
Cis-regulatory effect of HPV integration is constrained by host chromatin architecture in cervical...

Cis-regulatory effect of HPV integration is constrained by host chromatin architecture in cervical...

Human papillomavirus (HPV) infections are the primary drivers of cervical cancers, and often the HPV DNA gets integrated into the host genome. Although the oncogenic impact of HPV encoded genes (such...

biorxiv.org
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Very happy to present my work on prognostic association of immunoproteasome in solid tumors at #EMBOcancerEvolution workshop at Rimini,Itlay. Interesting talks, a lot of feedbacks and a great location!! #Cancergenomics
Image from Rahul kumar (@kumar99_rahul)
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Break it down.
Image from Lalit Patnaik (@lalitpatnaik)
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