Janez Konc (@koncj) profile picture

Janez Konc

@koncj
Joined August 2017
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ProBiS-Dock Database: A Web Server and Interactive Web Repository of Small Ligand–Protein Binding Sites for Drug Design pubs.acs.org/doi/10.1021/acs…

ProBiS-Dock Database: A Web Server and Interactive Web Repository of Small Ligand–Protein Binding...

Abstract. We have developed a new system, ProBiS-Dock, which can be used to determine the different types of protein binding sites for small ligands. The b

pubs.acs.org
2
New Research: Molecular Dynamics Simulations Reveal Interactions of an IgG1 Antibody With Selected Fc Receptors: In a survey of novel interactions between an IgG1 antibody and different Fcγ receptors (FcγR), molecular dynamics simulations were… frontiersin.org/articles/10.… #chemistry
Frontiers | Molecular Dynamics Simulations Reveal Interactions of an IgG1 Antibody With Selected Fc...

Frontiers | Molecular Dynamics Simulations Reveal Interactions of an IgG1 Antibody With Selected Fc...

In a survey of novel interactions between an IgG1 antibody and different Fcγ receptors (FcγR), molecular dynamics simulations were performed of interactions ...

frontiersin.org
2
1
Loop Grafting between Similar Local Environments for Fc-Silent Antibodies pubs.acs.org/doi/10.1021/acs…
Loop Grafting between Similar Local Environments for Fc-Silent Antibodies

Loop Grafting between Similar Local Environments for Fc-Silent Antibodies

Abstract. Reduction of the affinity of the fragment crystallizable (Fc) region with immune receptors by substitution of one or a few amino acids, known as

pubs.acs.org
1
Binding site comparisons for target-centered drug discovery tandfonline.com/doi/full/10.…

Binding site comparisons for target-centered drug discovery

Introduction: The success of binding site comparisons in drug discovery is based on the recognized fact that many different proteins have similar binding sites. Indeed, binding site comparisons hav...

tandfonline.com
CANDOCK: Chemical atomic network based hierarchical flexible docking algorithm using generalized statistical potentials biorxiv.org/content/early/20…
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BoBER: web interface to the base of bioisosterically exchangeable replacements jcheminf.springeropen.com/ar… #jcheminf
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