Brian retweeted
What if a foundation model could align histology, spatial biology & clinical data to reveal latent biomedical insights?
🚀 Introducing Haiku — a tri-modal foundation model trained on 26.7M+ spatial proteomics patches with matched H&E and clinical text, aligned in one shared embedding space.
📄 arxiv.org/abs/2605.00925
🧵👇
Brian retweeted
🚀 Introducing OpenResearcher: a fully offline pipeline for synthesizing 100+ turn deep-research trajectories—no search/scrape APIs, no rate limits, no nondeterminism.
💡 We use GPT-OSS-120B + a local retriever + a 10T-token corpus to generate long-horizon tool-use traces (search → open → find) that look like real browsing, but are free + reproducible.
📈 The payoff: SFT on these trajectories turns Nemotron-3-Nano-30B-A3B from 20.8% → 54.8% accuracy on BrowseComp-Plus (+34.0).
🧩 What makes it work?
🔎 Offline corpus = 15M FineWeb docs + 10K “gold” passages (bootstrapped once)
🧰 Explicit browsing primitives = better evidence-finding than “retrieve-and-read”
🎯 Reject sampling = keep only successful long-horizon traces
🧵 And we’re releasing everything:
✅ code + search engine + corpus recipe
✅ 96K-ish trajectories + eval logs
✅ trained models + live demo
👨💻 GitHub: github.com/TIGER-AI-Lab/Open…
🤗 Models & data: huggingface.co/collections/T…
🚀 Demo: huggingface.co/spaces/OpenRe…
🔎 Eval logs: huggingface.co/datasets/Open…
#llms #agentic #deepresearch #tooluse #opensource #retrieval #SFT
Unpopular opinion: PKM is like a "porn" for people who want to be productive but build nothing of "long-lasting" values.
Brian retweeted
clone any voice with a 5-second audio clip.
VoxCPM is an open-source project that takes a fundamentally different approach to text-to-speech.
most TTS systems convert speech into discrete tokens. this creates a bottleneck that limits how natural the output can sound.
VoxCPM skips tokenization entirely. it models audio in continuous space using an end-to-end diffusion autoregressive architecture.
the result is speech that actually sounds human.
here's what makes it special:
> context-aware generation: it reads your text and infers the right prosody, emotion, and pacing automatically. no manual tuning required.
> zero-shot voice cloning: give it a short audio clip, and it captures not just the voice, but accent, rhythm, and emotional tone.
the model was trained on 1.8 million hours of bilingual data (English and Chinese)
- supports streaming synthesis
- works with both full fine-tuning and LoRA
- simple Python API: `pip install voxcpm`
VoxCPM1.5 runs at 44.1kHz sampling rate with 800M parameters. so this is noticeably crisper and more natural.
it's Apache-2.0 licensed, so you can actually use it in production.
link to the GitHub repo in the next tweet.





