Co-Founder/COO of 3D body tracker @shapescale. 💪 Data & fitness tech geek, dad and husband. 🏃👊🔥

San Francisco Bay Area
Joined February 2009
Wouldn't be surprised. You can almost not browse any accounts with default Muse browser these days.
Prediction: you’re all going to be using @AsideAI with your agents in a year or so
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This is pretty cool.
Plus up your furniture with 3D-printed accessories using Gemini 4 Argon. Upload a pic with rough measurements, and use Canvas in Gemini to build an interactive 3D CAD studio where you can explore styles, tweak live sliders, and export printable STLs to upgrade your space.

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... and resets every other day! 🫠 Otherwise I'd probably get more out of Opus/Sonnet/Haiku.
Token spend has moved from Anthropic to OpenAI because - Luna is the king of small closed models - Sol 6.1 is an excellent every day driver for non-coders - Astra for coding is amazing, if you can afford it. Less dense than Fable Overall OpenAI has a very solid model family
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Martin Kessler retweeted
A hundred years ago, if your kid got diabetes, the doctor's plan was to starve them. 400 calories a day. Some weeks, nothing at all. It sounds insane but there was a grim logic behind it. Type 1 diabetes killed children within months back then, and less food meant less sugar in the blood, which slowed the dying. Kids on the diet stopped dying of diabetes and died of starvation instead, just slower. Parents signed up anyway because one extra year with their child was the best medicine could offer. Elizabeth Hughes was the daughter of the US Secretary of State, so she got the best care money could buy. That care took her from 75 pounds at diagnosis down to 45 pounds by age 14. When her mother brought her to Toronto in August 1922, she could barely walk. The treatment waiting there almost never got made. Frederick Banting was a small-town surgeon whose practice was failing so badly he was nearly broke. He talked a university into lending him a lab for one summer, and with a 21-year-old student assisting, isolated the pancreatic hormone researchers had chased for 30 years. Five weeks after her first shot, Elizabeth was eating 2,500 calories a day with a pint of cream poured on top. She gained 60 pounds in four and a half months. She went to Barnard, raised a family, lived to 73, and kept the diabetes secret from almost everyone she knew. Banting refused to put his name on the patent. He'd sworn the Hippocratic oath and believed a doctor had no business profiting from something like this. His co-discoverers sold it to the University of Toronto for a dollar. "Insulin does not belong to me, it belongs to the world." 24 months from first injection to the Nobel Prize, and every diabetic kid on earth went from a death sentence to a normal life for the price of one dollar.
In 1922, this little girl was wasting away from type 1 diabetes. Four months after doctors gave her a new experimental drug called insulin, she looked like a different child.
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Martin Kessler retweeted
Exercise, the low cost way to "reverse aging" science.org/doi/10.1126/scit…
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Martin Kessler retweeted
hey apple, this is what i want.
Welcome HomeView
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The Wegovy pill may be doing something more important than taking market share from injectable GLP-1s: expanding the obesity treatment market. A new study published in Annals of Internal Medicine examined the early uptake of oral semaglutide following its January 2026 launch. The numbers are pretty remarkable: 🔹100,000 new monthly prescriptions by month 2**, compared with month 4 for Zepbound and month 20 for injectable Wegovy. 🔹4.4x faster early adoption** than Zepbound and 7.4x faster than injectable Wegovy, based on launch-aligned prescription growth. 🔹Injectable Wegovy prescriptions did NOT decline following the pill's introduction. 🔹Total Wegovy prescriptions (oral + injectable) increased substantially, although Zepbound continued to lead in overall prescription volume. Here's what I find most interesting: The introduction of an oral GLP-1 appears to be expanding the market rather than simply cannibalizing injectable therapies. This makes intuitive sense. Some patients don't want injections. Others may find a pill more approachable, even with the inconvenience of daily fasting administration. Of course, these are aggregate prescription data, so we can't definitively establish how many new patients entered treatment versus switched therapies. But the broader implication is exciting. We may have substantially underestimated the number of people willing to pursue pharmacotherapy for obesity once we offer them more choices. And with additional oral obesity medications in development, this market could look very different in a few years. Source: acpjournals.org/doi/10.7326/…
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An AI health assistant in China reportedly surpassed 100 million users, offering services including free medical-report interpretation. While not a replacement for doctors, it shows how quickly access to health information can scale. The opportunity is enormous.
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Martin Kessler retweeted
11% of U.S. adults now take a GLP-1 for weight loss, roughly 28 million people, up from just 3% in 2024, per Gallup.
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Martin Kessler retweeted
I was at an AI dinner last night in NYC. Some interesting topics discussed 1. Performance engineers now spend most of their time managing agents and RSI loops. Most perf opts at major inference providers (together, fireworks) are found by agents. 2. RLing too much on code and math has negative effects on your model especially it’s language. 3. People were impressed by @bot and the overall acquisition of @cursor_ai by @spacexai. xAI is a legitimate frontier lab right now. 4. Most people have agents in loop writing, reviewing, and submitting PRs 24/7 5. Most agreed code review is not super productive anymore 6. Consensus was Fable 5.5 will be stunning but OpenAI will beat it in December with Bel
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Martin Kessler retweeted
GLP-1 prescriptions to healthy US adults went up 15x from in 4 years (2021-2025). None of them had type 2 diabetes or qualifying obesity. This tells me that the market for healthy people who want to become healthier is as big as the market for sick people. It's probably bigger. Healthy people want more energy, sharper focus and, ultimately, more good years. That's how GLP-1s went from a diabetes drug to a weight loss drug, and now to a lifestyle drug. I personally take retatrutide for focus as well, so I don't have to think about food. The same thing happened to tadalafil. It was an ED pill, and now people take it for longevity. I believe this is one of the signs that we are moving from sick care to performance medicine.
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It’s a bad sad when your best local model is now worse than Haiku. 😮‍💨
Btw GLM 5.3 Flash (had codex go find the results, could be off)
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Entering the Napster era
It's insane to watch AI blow apart closed source software and games. 4 examples from the past month: 1. 7 of Adobe's biggest apps, including Photoshop, Premiere, and Lightroom, have been partially rebuilt in Rust with Opus 5.5 and open sourced. It's still early, but the developer thinks they can match Adobe's features within months. Adobe's all-apps plan costs $840/year.
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That’s huge. Will be quite expensive for them if true.
Important note regarding Grok @Bot: Going forward, @SpaceX will use the best back end model for any given task, including Claude Opus 5.5, MidJourney, Suno and other leading APIs. Whatever is most likely to give you the best outcome.
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Martin Kessler retweeted
Amazon banning agents is the first opportunity I've seen since Amazon was founded for a startup to create an Amazon competitor. People will want agents to buy stuff for them. It will be one of the main use cases. And they won't want to use some Amazon-supplied agent to do it.
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Martin Kessler retweeted
15 years for an iPad app for Instagram. 30 days for an iPad app for Muse.
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Martin Kessler retweeted
Mobile advertisers watching the open-web ad industry realize that Apple exerts absolute authority over its platform:
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Ha, I was reading this post on Reddit and it made me think that I'm not really using my Dots to the fullest (mostly been orchestrating Codex sessions). Turns out it can run Blender on its virtual machine and since Dots uses Astra it's pretty capable. But boy rendering is SLOW.
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Let's see what comes of it when I wake up :D
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