Delighted to share the publication of the #EDICA study in @JCardFail doi.org/10.1016/j.cardfail.2… In patients 🏥 with acute HF, a natriuresis/diuresis-guided decongestion strategy (@escardio guidelines) vs a weight-guided one showed: ✅ Greater 5-day NT-proBNP reduction 🟰 5-day clinical decongestion 🟰 Length of stay & 30-day outcomes (🏥/☠️) 🟰 Safety & feasibility 🔎 Trend toward not sustained ⬆️ 24–48 h diuresis, weight loss, & loop-diuretic dose Some conclussions: 1️⃣ Time matters: earlier identification of diuretic resistance improves biomarker decongestion 2️⃣ Yet this did not translate into better short-term clinical outcomes 🎯Still need to close the gap between decongestion and clinical outcomes: Timing of assessment? Faster titration? Earlier combination diuretic therapy? Thanks to the great collab of Cardiology - Internal Medicine - Emergency Dep @MartaCoboMarcos @JanBiegus @esthermonteroh @fernidom @DeCastro9 @dr_pavia @segoviajavierve @ICardiacaSEC @secardiologia @CardioRenalSEC @HospiPtaHierro @Sociedad_SEMI @IcyfaSemi @SEMES_