@jaykoyner

father, husband. @uofcneph @uchicago come for the ICU-Nephrology, stay for #nephBBQ. figuring things out one CRRT machine and one rack of ribs at a time.

 Chicago IL
med-faculty.bsd.uchicago.edu/Default/Details/7158
Joined February 2015
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457Media
I know I’m old because podcasting makes me really happy A good hang with @keepingitrenal and @jaykoyner talking about AKI Follow-up and Recovery
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Happy @ASNKidney #Kidneyweek2027 Abstract Day to all who celebrate.
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While not a positive study, it was a positive experience and we learned a lot. Thanks to all those @uofcneph and @UW_ICU_DataSci who helped make it happen. There will be more to come; the story of using ML-risk scores to trigger AKI care is not over....
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It was a lot of work. Implementing a real-time machine-learning risk score in the EHR, identifying and enrolling high-risk patients before they had SCr-based AKI, randomizing them to a structured in-person nephrology consult. Excited to see it in press. ja.ma/44Wj6hm

Early Nephrology Consult and Acute Kidney Injury in Hospitalized Patients

This randomized clinical trial assesses whether a structured early nephrology consultation triggered by a machine-learning acute kidney injury (AKI) risk score in patients at high risk for AKI...

jamanetwork.com
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Inpatients at risk for #AcuteKidneyInjury identified by a machine-learning score did not benefit from early nephrology consultation, as changes in serum creatinine and outcomes were similar to usual care. ja.ma/44Wj6hm
RCT: Early Nephrology Consultation for AKI in hospitalized patients. Pop: 102M, 78F, median age 62.5. From 1 Chicago hospital. 180 randomized (89 ENC, 91 usual care). No significant difference in peak SCr change between groups (P=.30). ENC group shows slight SCr increase, usual care slight decrease.

ALT RCT: Early Nephrology Consultation for AKI in hospitalized patients. Pop: 102M, 78F, median age 62.5. From 1 Chicago hospital. 180 randomized (89 ENC, 91 usual care). No significant difference in peak SCr change between groups (P=.30). ENC group shows slight SCr increase, usual care slight decrease.

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Jay Koyner retweeted
Linda Awdishu@LAwdishuMay 19
Have you registered yet? It’s going to be a terrific conference!
Linda Awdishu@LAwdishuApr 30
Come join the conversation on hypertension guidelines and novel drugs for complex hypertension in sunny San Diego!
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Today, we set up a whole new WiFi system in the house. It went as smooth as possible. But there was a 25-min period of total blackout, no WiFi, no nothing - so today I was just like those astronauts who were out of communication on the far side of the moon. Mission accomplished!
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Thrilled to announce that MIMIC-IV-Ext-CLIF is now available on physionet! Download today and accelerate your ICU data science- the Common Longitudinal ICU data Format (CLIF) consortium (1 M critical illness hospitalizations) will run any well coded project written using this resource!
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Replying to @ISNkidneycare @KIReports @jradnephro @SumitMohanMD @sophia_kidney @StephenPastan @ghobby @AgarwalRajivMD @deniise_am @DrSumanBehera
➡️ A Comprehensive Framework for Kidney Function Assessment: Summary of the NIDDK Re-imagining Kidney Function Assessment Workshop kireports.org/article/S2468-…
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COYS!!!!
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Excited to see this work, collaboration with @UW_ICU_DataSci @uofcneph, on our deep learning recurrent neural network to predict severe AKI 2 days earlier than creatinine, published in @asnpublications. It is already implemented and validation studies are actively enrolling.
ASN Publications
@asnpublications15 May 2025
Multimodal AKI risk score accurately identifies patients who will develop Stage 2 AKI over two days earlier than serum creatinine alone. bit.ly/CJASN0695 #ASNCJASN
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Multimodal AKI risk score accurately identifies patients who will develop Stage 2 AKI over two days earlier than serum creatinine alone. bit.ly/CJASN0695 #ASNCJASN
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Her passing is a huge loss for the community and all we serve in medical education. pritzker.uchicago.edu/news/h…

Honoring the Legacy of Dr. Holly J. Humphrey

Holly J. Humphrey, MD, MACP, 1956-2025

pritzker.uchicago.edu
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