Cardiac Electrophysiology | @MappingLab_EP #opticalmapping #microelectrodearray #Langendorff #calcium #actionpotential #heart #AF https://xitter.cf/t.co/PhpsIYdFx9
Joined March 2020
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A quick overview of Optical Mapping System for cardiac electrophysiology research.
Effortlessly record cardiac membrane potential and calcium transient.
#opticalmapping #cardiotwitter #Cardiology #arrhythmia #heart @MappingLab_EP
In this video, the Optical Mapping System is used to record Ca transients from rat cardiac tissue slices during electrical stimulation, enabling high-resolution visualization of Ca dynamics and signal propagation across tissue & showing how cardiac tissue responds
@MappingLab_EP
Jay Lu, DPhil retweeted
Thrilled to share the Hamilton lab has received our first Notice of Award for an NIH R01; ‘The roles of endoplasmic reticulum stress in cardiac arrhythmias’. I am so grateful to NHLBI and those who supported us to get here. Stay tuned for postdoc position…
Beyond reducing arrhythmias, can a therapy restore cardiac electrical conduction? MEA electrical mapping provides the answer by directly measuring conduction velocity, activation patterns, and electrical heterogeneity.
Jay Lu, DPhil retweeted
Hard to compete with the World Cup tomorrow, but hope you join us! Thank you to @sgpweb @OsamaHarraz and EpIC for the invite!
Join us for the next SGP EpIC Seminar on Tuesday, 7 July 2026, at 12:00 pm Eastern featuring a talk by Shanna Hamilton @S_HamiltonLab on “The cardiac ryanodine receptor: effects of calcium release beyond excitation-contraction coupling." As ever, registration is free and all are welcome: sgp-epic-seminars.com
We are now exhibiting at @ISHR_NAS. Feel free to visit our booth if you re around.
Jay Lu, DPhil retweeted
A new study shows that inherited arrhythmias like CPVT are not driven by cardiomyocytes (CM) alone.
Using hiPSC-derived neuro-cardiac models, the team found dysfunctional sympathetic neurons can trigger #arrhythmia in otherwise healthy CM.
#electrophysiology #cardiology #mapping
Jay Lu, DPhil retweeted
One of the simplest ways to record field potentials and ECG in a Langendorff heart preparation.
Simply apply microelectrode arrays and ECG electrodes directly to the heart.
#CardioTwitter #Electrophysiology #ElectricalMapping #DrugScreening #Cardiotoxicity #iPSC #Heart
Jay Lu, DPhil retweeted
Thrilled to share our new preclinical paper: low-dose (nonablative) cardiac radiation reduces VT/VF in NICM — associated with improved ventricular conduction and sympathetic nerve distribution.
Grateful for our stellar team: @alicardsdoc @carmenbergom @drlpedersen @doctorphillep @rentschlerlab and first author Devaki Abhyankar.
🔗 doi.org/10.1016/j.jacep.2025…
#Electrophysiology #VT #CardioOncology #TranslationalScience @uclahealthnews @jaccjournals
Thrilled to share our new preclinical paper: low-dose (nonablative) cardiac radiation reduces VT/VF in NICM — associated with improved ventricular conduction and sympathetic nerve distribution.
Grateful for our stellar team: @alicardsdoc @carmenbergom @drlpedersen @doctorphillep @rentschlerlab and first author Devaki Abhyankar.
🔗 doi.org/10.1016/j.jacep.2025…
#Electrophysiology #VT #CardioOncology #TranslationalScience @uclahealthnews @jaccjournals
Jay Lu, DPhil retweeted
The first gene-edited miniature pig model of LQT2 is here.
By combining ECG telemetry, electrical mapping, and optical mapping, this study delivers a truly translational view of hERG-related arrhythmias in a large-animal heart.
Short version:
bit.ly/4jaguCV
Jay Lu, DPhil retweeted
Calcium and Contractility Mapping System: An Integrated Solution for Cardiac Research
open.substack.com/pub/jayjay…
#Cardiology #cardiomyocytes #ipsc #mapping #calciumimaging #opticalmapping
Jay Lu, DPhil retweeted
Yu et al. (2025) showed that an Andr-loaded atrial patch prevents POAF by reducing inflammation, oxidative stress, and calcium imbalance. In a rat model, it lowered Afib incidence from 90% to 20% and protected heart cells, highlighting a promising targeted therapy for POAF.
Jay Lu, DPhil retweeted
Unlock the mysteries of cardiac arrhythmias with our advanced Electrical Mapping System! High precision data acquisition and MEA provide unparalleled insights into electrical activity at the tissue level. Perfect for anti-arrhythmic drug screening and toxicity testing.
Calcium and Contractility Mapping System: An Integrated Solution for Cardiac Research
open.substack.com/pub/jayjay…
#Cardiology #cardiomyocytes #ipsc #mapping #calciumimaging #opticalmapping
Our electrical mapping workflow offers a fast and accessible way to measure epicardial field potentials — ideal for quick assessments in drug testing and disease models. ⚡❤️
#activationmap #electrophysiology #Langendorff #drugscreening #cardiotwitter #Cardiology
Jay Lu, DPhil retweeted
Come to join us for exchanging ideas and networking with colleagues and friends.
🫀 A healthy heart requires intricate crosstalk between different cell types to keep it functioning well. We shall explore these interactions over the next two days at #HeartCrossTalk2025 @unibirmingham.
View today's line up of speakers and topics ⬇️ buff.ly/ZqCSNzT
Jay Lu, DPhil retweeted
Excited to share the Langendorff technique for heart cannulation—an excellent method for advancing functional studies 😎
#CardioTwitter #MedTwitter #Langendorff #electrophysiology #heart #Cardiology #opticalmapping #electricalmapping #MEA