@janeslab

Systems biology lab @ UVA BME Interested in engineering approaches for signal-transduction and transcriptional networks.

 Charlottesvile, VA
systemsbioe.org/
Joined July 2019
  • Tweets40
  • Following115
  • Followers341
5Media
Congratulations to Kevin, @RPrzanowska, and Najwa for being featured in UVA Engineering News for their cutting-edge work with patient-derived breast cancer organoids! engineering.virginia.edu/new…
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You can check out the original journal article here: breast-cancer-research.biome…

Patient-derived response estimates from zero-passage organoids of luminal breast cancer

Breast Cancer Research - Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways...

link.springer.com
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Congrats to all for a successful SASCO symposium and @NCIsysbio site visit! news.med.virginia.edu/resear… The Hot Ones career advising panel was a terrific success (thanks to Iylan from @sepiddsh lab and Jen from @kashatuslab for participating).
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Congratulations to Catalina for earning an ASPIRE fellowship from the Susan B. Komen foundation! news.med.virginia.edu/resear… @SascoVirginia @NCIsysbio

Komen Supports UVA Engineering Researchers Targeting ‘Triple Negative' Breast Cancer - Research -...

Through precision medicine, the University of Virginia is working toward a world in which no more pink ribbons are necessary. To that end, Susan G. Komen announced support for the UVA School of...

news.med.virginia.edu
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Great week for the lab with two new and very different preprints posted: biorxiv.org/content/10.1101/… biorxiv.org/content/10.1101/…
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Nothing beats a -80ºC failure on Labor Day evening. Thanks to the team who could make it in on short notice!
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Lab members Najwa Labban, @taylormarohl, and @WeAndThenSam presented their work at #NCIJI2023 earlier this month and brought home an award and honorable mention!
Wisam Fares - Poster Presentation Award

ALT Wisam Fares - Poster Presentation Award

Taylor Marohl - Poster Presentation Honorable Mention

ALT Taylor Marohl - Poster Presentation Honorable Mention

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Check out our latest preprint that statistically relates mRNA-protein abundances to make protein copy number estimates from transcriptomics! A web tool was also developed to make the estimates broadly available. @AndrewSweatt1 @CamTheVirusGuy @paudelbb biorxiv.org/content/10.1101/…

Proteome-wide copy-number estimation from transcriptomics

Protein copy numbers constrain systems-level properties of regulatory networks, but absolute proteomic data remain scarce compared to transcriptomics obtained by RNA sequencing. We addressed this...

biorxiv.org
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Check out this work done by @JianhaoZeng1 from Zong Lab in collaboration with @aycatalina24 and Lixin Wang in Janes Lab! Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model sciencedirect.com/science/ar…
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Janes Lab BBQ 2023!
Janes Lab posing for a picture outside.

ALT Janes Lab posing for a picture outside.

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Pleased to share our lab's most recent work! Congratulations @paudelbb, Lixin, and Anthony! @SascoVirginia @UVABME
Bishal Paudel@paudelbb13 Apr 2023
Happy to finally see our work on nucleocytoplasmic transport of HER2 and multicellular fate published on @NatureComms today. Thanks to @janeslab, Lixin, and Anthony for an exciting collaboration. @UVABME, @SascoVirginia. Lastly, thanks to @NCIsysbio #CSBC nature.com/articles/s41467-0…
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Exciting new Janes Lab preprint from Lixin, @paudelbb , and Anthony on ErbB signaling, nucleocytoplasmic transport, and breast cancer systems biology: biorxiv.org/cgi/content/shor… @SascoVirginia
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Janes Lab had a great time at #SACB2022. So much amazing research and even more amazing people. Can't wait to see everyone again at SACB 2024.
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Happy to announce the release of the SASCO U54 web page: sasco.virginia.edu Come see the cancer sys bio plans at UVA. @janeslab @LazzaraLab @kashatuslab @papinsysbio @MFallahiSichani @Kristen_naegle @hui_zong @shaynalefrak @Kristen_atkins @NCIsysbio
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Be sure to follow the latest on our new U54 Center of the NCI Cancer Systems Biology Consortium @SascoVirginia!
sasco.virginia@SascoVirginia14 Sep 2022
We are excited to announce the Systems Analysis of Stress-adapted Cancer Organelles (SASCO) U54 Center of the NCI-sponsored Cancer Systems Biology Consortium! @janeslab @LazzaraLab @kashatuslab @papinsysbio @MFallahiSichani @Kristen_naegle @hui_zong @shaynalefrak @Kristen_atkins
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New this year, for #SACB2022, we are offering scholarships to young investigators/trainees to encourage more participation in the meeting. The application can be found at tinyurl.com/y7afr93e or directly from the SACB website (sacbmeeting.org) Deadline is August 19th!
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Janes Lab retweeted
Virginia BME@UVABME22 Jul 2022
Announcing UVA's newest pre-doctoral training grant in Systems & Biomolecular Data Sciences, funded by the National Institutes of Health. Co-PIs are Jason Papin + Kevin Janes, and the 1st cohort of PhD students is selected! @papinsysbio @janeslab @UVAEngineers @uva_bims
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Congratulations to Dr. Kevin Janes for being selected as a John Marshall Money Professor of Biomedical Engineering!!!
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Congratulations to Dr. Kevin Janes for receiving this year's Research Mentor Award from the VPR's office! This award recognizes faculty members for their dedicated and extraordinary efforts to help junior faculty succeed in their research careers. research.virginia.edu/2021-a…
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Excited to share work by Kai Song, the Graeber lab & collaborators, interrogating the interplay of BRAF focal amplification modes (extrachromosomal DNA (#ecDNA) & homogenously staining regions (#HSR)) in the context of MAPK inhibitor #cancer regiments. bit.ly/2ZqHWrK 1/2
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