General Surgery Registrar and Gut Microbiome Researcher
Birmingham, England
Joined July 2012
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James Halle-Smith retweeted
New #GUTScience paper by Halle-Smith et al entitled
"Gut microbiome composition is associated with response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma patients" via
bit.ly/4f6XRzg
#OA #PancreaticCancer @druppygill
Two people can receive the same chemotherapy and have completely different experiences.
Emerging evidence suggests that bacteria in the gut may contribute to the development of side effects.
This article explores the recent evidence and mechanisms ⬇️
open.substack.com/pub/microb…
James Halle-Smith retweeted
Are you a dietitian, Interested in doing a PhD and love the pancreas - then this is for you findaphd.com/phds/project/op…
@RoyalSurrey @GutsCharityUK @PancSocGBI
💡Does the gut microbiome affect how well neoadjuvant chemotherapy works in pancreatic cancer patients?
Our study just published in @Gut_BMJ science investigates how the gut microbiome differs according to chemotherapy response🧵
gutscience.bmj.com/content/1…
What does this mean? ⏭️
Altering the gut microbiome towards a more favourable phenotype has the potential to increase efficacy of existing chemotherapy drugs in pancreatic cancer. This could potentially be achieved through dietary modification or FMT
nature.com/articles/s41591-0…
Thank you to all those who contributed to and supported this research @beggs_lab @unibirm_CMH @UHB_HPB @adbeggs @TariqFMT @ThePancSocGBI @uhbtrust @PancreaticCanUK
Very proud of @jameshallesmith who is a clinical PhD supervised by @UHB_HPB and @beggs_lab for winning the Rodney Smith Medal @ThePancSocGBI meeting this week on “Pancreatic Exocrine
Insufficiency is associated with Gut Microbiome
Dysbiosis in Patients with PDAC”
James Halle-Smith retweeted
Doctors: use vignettes! 🧵
You’ve done a gazillion exams and what do all patient-based questions have? That’s right, a clinical vignette.
Heres a secret in medicine: you can use the “skill of the vignette” to get what you want and to communicate better than ever.
James Halle-Smith retweeted
Time to get fit and raise money. At 44yr it’s time to experience emotions of the @LondonMarathon 2025. Raising money for @PancreaticCanUK and privileged to be doing so. @UHBCharity @uhbtrust @unibirmingham @EASLnews @ExaltTrial #livertwiiter @AASLDtweets 2025tcslondonmarathon.enthus…
All hands to the pump! ⛽️🤲
Birmingham NRP team practising troubleshooting at the fantastic Edinburgh NRP masterclass 2024 @Bham_HPB_LTx @CentreEdinburgh
#NRPMasterclass – at Scotland, United Kingdom
Session 1: Bristol ✅
Session 2: Liverpool ✅
Session 3: Birmingham ✅
Session 4: Leeds ✅
Talks from experts at pancreatic units all over the UK as part of the webinar series for trainees and fellows on pancreatic cancer.
Second talk of this evening from Prof Smith (Leeds) – at Scotland, United Kingdom
4th session in the national pancreatic cancer webinar series for trainees and fellows.
This week’s first talk from the Leeds team and @Drsampathak talking about surveillance and recurrence after pancreatic cancer surgery @roux_group @UHB_HPB
James Halle-Smith retweeted
Great to see so much participation from the Birmingham HPB surgical team during the HPB sessions at #AUGIS2024! @Augishealth @uhbtrust @Bham_HPB_LTx @UHB_HPB @liveRPancSurg
Brilliant feedback for first session of national trainee webinar series on pancreatic cancer surgery with talks from @UHB_HPB on decision-making and Dr Karteszi from Bristol on Radiology in pancreatic cancer
Join next week for talks from Prof Ghaneh and Mr Dunne from Liverpool! – at Birmingham, England
Missed tonight? No problem - sign up below to join the mailing list. Talks are also recorded and will be made available soon.
forms.gle/zkkquQp3fXL69Cf57
@roux_group – at Birmingham, England
