Senior Research Fellow at Test and Prediction Group, University of Birmingham
Joined October 2013
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Great to see the first chapters of this much needed handbook for carrying out systematic reviews of diagnostic test accuracy coming out. Well done to all involved
It took a few years, but the first 3 editorial accepted chapters of the @cochranecollab's DTA Review Handbook are online.
(study designs; collecting data; understanding meta-analysis)
training.cochrane.org/handbo…
with @deeksj @pmmbossuyt Yemisi Takwoingi @EllaFlemyng Laura Mellor
Jac Dinnes retweeted
JOB opportunity for early career medical statistician in our team here @unibirmingham. Would suit new MSc/PhD graduate or with a few years experience, particularly interested in test evaluation. Work plan will include a variety of clinical projects.
jobs.ac.uk/job/CFW897/resear…
It was a real privilege to be part of this. There are a few great test evaluation studies out there but many more not so great. We hope this paper will help those planning new studies or interpreting those already published
Important paper in @bmj_latest from global leaders in test evaluation. Hope will improve quality of studies.
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Guidance for the design and reporting of studies evaluating the clinical performance of tests for present or past SARS-CoV-2 infection bmj.com/content/372/bmj.n568
Great summary of why confirmatory PCR after positive lateral flow tests is welcome but only one step toward improving testing programmes. Seems that support to isolate and better implementation protocols will be a step too far ...
Slight respite for a few days but we’re already well into another set of studies for the next update with more data from asymptomatic testing and hopefully real world evaluations of serial testing strategies
👇🏻
Updated @cochranecollab review of Rapid Tests for Covid-19 is here
Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection - @jacdinnes @deeksj - 2021 | Cochrane Library
cochranelibrary.com/cdsr/doi…
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Excellent read, especially love this “big data and machine learning offer an exciting chance for revolution, but revolutions demand greater scrutiny, not less”. ML has big potential but needs evaluating in the same way as any test before it’s benefits are understood
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Our BMJ blog on school testing - Consent can’t be informed if people aren't told the risks of having false results. We need direct evidence of benefits from testing in schools and proper support for families who need to self-isolate if a positive result is confirmed on PCR
How are the potential benefits and harms from lateral flow device testing being communicated to students, parents, and teachers?
@jacdinnes and Clare Davenport discuss the rollout of mass testing programmes in English schools ow.ly/tcow50E0cN6 #COVID19
Jac Dinnes retweeted
Just reading this utter statistical nonsense in the Telegraph....
telegraph.co.uk/technology/2…
Our latest Cochrane COVID-19 DTA review of point-of-care tests published today (thread): cochranelibrary.com/content?…
We are already extracting studies for the review update (searches to 22 Jul) but so far not many signs of improved study design and reporting. We can do so much better than this!!
👆Unfortunate that evaluations of Abbott's brand new BinaxNOW antigen test do not seem to be amongst them. How great would it be if these validation results (in symptomatic cases, 83% with high viral load) were shown to apply in practical settings ...
xitter.cf/michaelmina_lab/status…
Great work @TStruyf and @annvdbruel. A much needed insight into the need for more and much better studies into signs and symptoms of COVID-19
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Relieved to get the first of our living reviews of antibody test accuracy for COVID19 published!
Such a pleasure to work with this brilliant team @TERG_UoB @cochranecollab and beyond 🌟
A-b testing rates are rapidly rising so a few things to bear in mind ⬇️
JUST PUBLISHED - Antibody tests for identification of current and past infection with SARS‐CoV‐2 buff.ly/2Z8fZk3 Important Cochrane #COVID19 rapid review from @Cochrane_IDG
2. Tests can diagnose previous infection but there will be errors, especially false negatives. We don’t yet have evidence for how they work in people who had milder or no symptoms, or what happens to antibodies weeks after recovery ⬇️
And a reminder, having antibodies does not necessarily mean immunity! Lots more work is going on to learn about how the virus works 🦠
See @deeksj great summary of the review here
Antibody tests for identification of current and past infection with SARS‐CoV‐2 - Deeks, JJ - 2020 | Cochrane Library cochranelibrary.com/cdsr/doi…
Living Cochrane Review of Antibody Tests – 1st version now published. Twitter summary to save you reading the 300+ pages