Ivan Chan (@ivanylchan) header
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Ivan Chan

@ivanylchan

BBSRC PhD Student at UoM with interests in Helicobacter, infection, phages and AMR 🧬🧫🦠💊

 United Kingdom
Joined August 2017
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Photo by Ivan Chan (@ivanylchan)Photo by Ivan Chan (@ivanylchan)
Thrilled to have presented my talk and poster at #CHRO2024 in stunning Perth, Australia. 🧫🧪🌅 An unforgettable experience made even more special by meeting Nobel laureate Prof. Barry Marshall.
Image from Ivan Chan (@ivanylchan)
Image from Ivan Chan (@ivanylchan)
Image from Ivan Chan (@ivanylchan)
Image from Ivan Chan (@ivanylchan)
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Very interesting and exciting two days at #Microbio24 Pop by poster booth B366 if you want to hear about about my PhD year 1 work on metal-handling systems in Helicobacter pylori!
Image from Ivan Chan (@ivanylchan)
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New paper from @Cambridge_Uni & AMRHAI Reference Unit of @UKHSA (@juliana_tropic, @theAMRdoc, @IzziePotterill, et al). We report a novel Globicatella species causing soft tissue infection and tenosynovitis in an immunocompetent man after cat bite injuries. doi.org/10.3201/eid2908.2217…
Image from Yu Wan 万宇 (@wanyuac)
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Our discovery of widespread MDR Staphylococcus capitis NRCS-A clone in neonatal units across UK is published. This work was sponsored by @UKHSA, led by @aliciad3, Dr B Pichon, @cstewartb, supported by @NHSuk, @derren_ready, @Leginnyella, @ElitaJaun, et al. doi.org/10.1016/j.jinf.2023.…
Graphic abstract of the paper

ALT Graphic abstract of the paper

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Very pleased that our new paper is out! pubs.acs.org/doi/10.1021/acs… Excellent work from Josh @MIBTP1 and Jaimee (Mbio @WarwickLifeSci ) in collaboration with @Chen_group . Thanks to @BBSRC for funding!
Genetic Engineering of Bacteriophage K1F with Human Epidermal Growth Factor to Enhance Killing of...

Genetic Engineering of Bacteriophage K1F with Human Epidermal Growth Factor to Enhance Killing of...

Abstract. Bacterial infections are a major cause of human morbidity and mortality on a global scale. Many bacterial pathogens, such as Escherichia coli, ca

pubs.acs.org
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It’s officially out 🎉🎉 Very grateful to be part of this work during my URSS summer experience @WarwickLifeSci and special thanks to @MeeraUnnikri @JChengScience and everyone involved to make this happen. journals.asm.org/doi/10.1128…

Regulatory Role of Anti-Sigma Factor RsbW in Clostridioides difficile Stress Response, Persistence,...

Pathogens like Clostridioides difficile face a range of stresses in the environment and within the host. Alternative transcriptional factors like sigma factor B (σB) enable the bacterium to respond...

journals.asm.org
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I captured a bacterium #sneezing🤧 This E. coli bacterium is undergoing lysis (RIP) because of an infection with T4 #bacteriophages. It was forced by these viruses to build virus copies. Now they are released to infect other bacteria, kinda like sneezing on them. Gesundheit!
Several bacteria heavily infected with T4 bacteriophages. One of them is currently rupturing to release the phages so they can infect more bacteria. However, it seems like all bacteria in the vicinity are already infected, so this is a bit like sneezing in a room full of people who all have a cold already anyway

ALT Several bacteria heavily infected with T4 bacteriophages. One of them is currently rupturing to release the phages so they can infect more bacteria. However, it seems like all bacteria in the vicinity are already infected, so this is a bit like sneezing in a room full of people who all have a cold already anyway

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Why do some people develop persistent lung sequelae after severe COVID19? Our new PROSAIC consortium study now published @ScienceTM uses multi-omics to identify a causal role for neutrophils/NETS in driving this complication @ImperialInfect @ImperialNHLI science.org/doi/10.1126/scit…
A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae

A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae

Individuals with persistent interstitial lung changes following COVID-19 exhibit a systemic proinflammatory neutrophil-associated immune signature.

science.org
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New preprint from the lab… this has involved several lab members over the years… but finally led by ⁦@JChengScience⁩ . The regulatory role of anti-sigma factor, RsbW, in Clostridioides difficile stress response, persistence and infection | bioRxiv biorxiv.org/content/10.1101/… – at Coventry, England
The regulatory role of anti-sigma factor, RsbW, in Clostridioides difficile stress response,...

The regulatory role of anti-sigma factor, RsbW, in Clostridioides difficile stress response,...

Summary The anaerobic pathogen Clostridioides difficile , a primary cause of antibiotic-associated diarrhoea, faces a variety of stresses in the environment and in the mammalian gut. To cope with...

biorxiv.org
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Interested in learning the latest in bacterial infection biology and two research project placements in great labs? Look into our MRes programme in the Bacterial Pathogenesis & Infection stream. Admissions open, apply early! @CMBI_Imperial imperial.ac.uk/study/pg/medi…

Biomedical Research (Bacterial Pathogenesis and Infection) MRes

Training in the fundamental aspects of bacterial pathogenesis for a career in biomedical research.

imperial.ac.uk
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