Toronto, Ontario
Joined April 2016
Ismail Raslan retweeted
VLADDY SAFE AT THE PLATE. OH MAN. 🔥
57
544
149
4,408
383,026
To any health care institution or headhunter seeking world-class physicians and surgeons, the Quebec legistlature has passed a new special law severly impacting the civil and professional liberties of medical practitioners in our province, where average remuneration was already one of the lowest in North America, in a jursidiction with one of the highest tax rates in the world. You now have the opportunity to recruit top medical talent to your institution! Quebec medical professionals are accustomed to working in a resource limited setting, in high-volume practices for discounted rates. Now's your chance to recruit and you can thank @cdube_sante, @francoislegault and the @coalitionavenir for this health care fire sale!
30
19
8
86
38,826
Ismail Raslan retweeted
George Springer blew the roof off the entire city of Toronto
135
1,480
146
16,137
738,101
Is this the end of rivaroxaban for acute VTE? @LanaCastellucci presenting the COBBRA trial - 1st RCT comparing apixaban to riva over 3 months. 56% reduction in bleeding risk with apixaban. A safer Rx with the same efficacy. #ISTH2025
10
124
8
349
35,359
Ismail Raslan retweeted
Hot off the press! COBBRA trial showed that apixaban is associated with >50% reduced risk of clinically-relevant bleeding symptoms for acute VTE treatment. This can be practice changing! @LanaCastellucci @RodgerMarc @canvector
5
40
3
109
14,006
Ismail Raslan retweeted
Three cured #sicklecell persons in one room this am. #haplobmt. Never thought I'd see the day.
1
9
1
78
5,598
On International Day of Women and Girls in Science, learn about a unique, women-founded, multidisciplinary clinic at St. Michael’s that provides treatment, care, support and education for women with bleeding disorders – and their babies. unityhealth.to/2025/02/multi…
7
19
881
Almost 120 years since Thomas McCrae (younger brother of LCol. John🇨🇦) described these cytoplasmic inclusions known today as Aeur rods. My yearly plea for morphologists to rename them. Auer rods or McCrae rods? - Barbara J. Bain AJH onlinelibrary.wiley.com/doi/… @DavidSteensma
1
15
1,274
Thrombosis rates are much higher in patients receiving high dose andexanet (as are death rates - more on efficacy in next thread)
1
1
3
583
FDA's own review of thrombotic events reported 12 extra cases – 9 in andexanet & 3 in usual care – that were not assigned as thrombotic by blinded committee. Sorry, I don’t have more info on this! Final figures (based on n=471 FDA safety set): 14.6% vs 6.9%, stroke 5% vs 0.4%.
1
2
3
925
1/ FDA hearing on #andexanet alfa is tomorrow (21 Nov 2024). The documents contain some more data on thrombotic events that weren't published in ANNEXA-I. To be honest, reading through, I have found this data pretty shocking. A 🧵
4
69
4
276
68,122
👇🏻👇🏻👇🏻 Important key data re annexa-I
Replying to @richardbuka
Nevertheless, the rate of thrombosis in patients who DID NOT received any anticoagulation was a whopping 26% vs 10% in the usual care arm. The other thing here is that restarting anticoagulation does not prevent events, as we have been led to believe previously.
1
5
710
Ismail Raslan retweeted
The KDIGO 2025 Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD) is available for public review through Friday, November 22. You can download the public review draft and share comments via the feedback survey on the KDIGO Anemia in CKD Guideline Website: kdigo.org/guidelines/anemia-… KDIGO will prepare a final version for publication based on feedback received during public review. We thank you in advance for your time and insights. #anemia #CKD
1
182
8
520
32,399
Ismail Raslan retweeted
Great presentation by Dr. @Pharmacist_MTL on the importance and relevance of @AnticoagForum Stewardship in Canada. Approx 65% of admitted patients need anticoagulation adjustments (type , dose), de-prescription of anti-platelets, etc. Avoiding complications and improving outcomes
1
4
1
15
2,498
Ismail Raslan retweeted
FcRn-targeting drugs are the new kid on the immuoheme block with many realized and potential uses in Heme and Transfusion patients Co-authors @path_brian @jeremy et al have written an incisive review on the present and future of FcRn agents @AjHematology doi.org/10.1002/ajh.27487
1
4
17
1,793
Ismail Raslan retweeted
The study (GABA-WHY) ran during his fellowship with the help of Iman Huseen and Kristen Moran, our amazing research assistants. It's published today in @JAMAInternalMed Briefly, by giving patients these brochures, we increased deprescribing by 13%! jamanetwork.com/journals/jam…
3
3
10
1,060
Very pleased to see this in the mail today! Congrats to @sholzberg and team in bringing impactful change after years of advocacy and hard work. @LifeLabs
1
2
19
6,322