Neuroscientist & psychologist @HarvardMed & @McLeanHospital. PTSD & trauma. #academictwitter, #WomenInSTEM. Views mine. she/her, @irosso.bsky.social
Boston, MA
Joined April 2009
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🚨New pub🚨 on the restless hippocampus and trauma memories. We link dynamic hippocampal-cortical coactivations to daily experiences of intrusive trauma memories in PTSD. A tale of collabs and bridging cog neuro w/ lived-experience reports via EMA 🧵
nature.com/articles/s41380-0…
Isabelle Rosso retweeted
🆕in DPN from our EB member Nate Harnett & @_brainstorm_12, @irosso et al:
Traumatic stress alters neural reactivity to visual stimulation
nature.com/articles/s44277-0…
NIH facing ‘devastating’ freezes on meetings, travel, communications, and hiring | Science | AAAS science.org/content/article/…
EMA study of dissociative episodes shows that heart rate does not change in relation to dissociation intensity, counter to "hypoarousal models" of dissociation. sciencedirect.com/science/ar…
Isabelle Rosso retweeted
New research alert!! Interpersonal trauma exposure is associated with altered neural event segmentation mechanisms. Insights into trauma-related memory deficits and perception! @irosso @e_a_olson link.springer.com/article/10…
Hi #ACNP2024, this is my 11th ACNP (!). Come see our posters on Monday to chat neuroimaging and digital phenotyping in PTSD, led by Steve Granger, Kevin Clancy, Nate Harnett. I'll also be helping with discussion @ table 61 of the Women and Gender Minority Luncheon .come join us!
We are officially on the ground in Phoenix so it's time for the #ACNP2024 role call 📣
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
Meta-analysis of psychological interventions for pediatric PTSD jamanetwork.com/journals/jam…
Isabelle Rosso retweeted
If you work at a government agency, CDC, FDA, CIA, FBI, NASA, NTSB, NOAA, anywhere, you need to start saving every gig of data you can find. Studies, organizational charts, employee manuals, policies and procedures.
Anything that can be used to recreate your agency from scratch.
This was a fun pub. As part of a larger study, we're using EMA to track trauma memories. Clinicians often ask us whether participants’ symptoms change during the EMA period. Great question, so we took a look! Congrats to first-authors Yara Pollmann and Kevin Clancy. More to come.
🆕in DPN:
Specific symptom change associated with ecological momentary assessments of intrusive trauma memories
@irosso & team @McLeanHospital show that 2 weeks of reporting on unique qualities of trauma memories leads to reductions in intrusion symptoms
nature.com/articles/s44277-0…
Isabelle Rosso retweeted
NEW lab logo + NEW job posting (link below)!
The Biological Embedding of the Environment and Stress (BEES) lab at #DukeUniversity is #hiring a full-time in-person research assistant to conduct human neuroimaging research on traumatic stress.
Congratulations MMHRSP trainees, and big thank you to the mentors and organizers. Lots of talent, hard work, and dedication in the picture below👇
Isabelle Rosso retweeted
Y'all, I am so proud of this paper! ⬇️ Where we live can influence our likelihood of developing PTSD! But research on resilience after trauma has often focused on individual 🧍 factors and overlooked influential neighborhood 📷factors that may help mitigate the PTSD development
Cross-regional coordination of activity in the human brain during autobiographical self-referential processing | PNAS pnas.org/doi/10.1073/pnas.23…
New pub in @BiologicalPsyc1, collaboratively across trauma research labs @McLeanHospital, led by Nate Harnett. We review the relevance of visual processing in PTSD, esp the impact of stress on affective-visual circuitry.
biologicalpsychiatryjournal.…
Isabelle Rosso retweeted
New research in @dpn_journal unveils potentially distinct patterns of default mode network (DMN) connectivity between posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) following mild acute stress. (🧵1/2)
rdcu.be/dLpKy
ALT Alterations of the Default Mode Network (DMN) connectivity strength are primarily localized in nodes of ventromedial prefrontal cortex (specifically, nodes of the left medial orbitofrontal, and of the right rostral anterior cingulate) and in the left precuneus. https://rdcu.be/dLpKy
Isabelle Rosso retweeted
Abstract:
✅Ketamine "tablets were effective, safe & well tolerated"
Actual results:
❌At primary endpoint of 13 weeks, 0 of 4 ketamine groups outperformed placebo /re remission
❌At 13 weeks, only 1 of 4 outperformed placebo /re response, with a beautiful p-value of 0.046 🤪
Extended-release ketamine tablets provide a promising alternative for patients with TRD who have not responded to other treatments.
Any thoughts @mehta_mitul72 @EikoFried
nature.com/articles/s41591-0…
Isabelle Rosso retweeted
Exercise blunts the cortisol response from an acute psychosocial stressor
Here’s how to use exercise to help manage stressful situations 👇
🧵1/8
Service Dogs for Veterans and Military Members With Posttraumatic Stress Disorder 🐕🦺🐕🦺
jamanetwork.com/journals/jam…
Isabelle Rosso retweeted
This is incredibly moving!
Please take 10 minutes to watch this.
Suicide can affect anyone.
Small acts of kindness can save lives.
If you are struggling, help is available:
@samaritans 116 123
Thank-you @Wolves
An incredibly powerful video by @Wolves, well done to them for raising awareness. 👏
Don’t suffer in silence, there is always somebody that will listen. ❤️
Isabelle Rosso retweeted
Thrilled to share our new publication in @NatMentHealth! We took a longitudinal, dynamic and transdiagnostic approach to define the r factor for post-trauma resilience that explains >50% of variance in mental wellbeing 6-months after #trauma (1/9) – nature.com/articles/s44220-0…
