@irma_querques

Structural bio(techno)logist | #NewPI at @MaxPerutzLabs | Mobile DNA lover & CRISPR newbie

maxperutzlabs.ac.at/research/research-groups/querques
Joined October 2017
  • Tweets379
  • Following554
  • Followers1K
1Media
📢 I have two open @ERC_Research fully funded #postdoc and #PhD positions in my lab at @MaxPerutzLabs on the @viennabiocenter campus. We are looking for structural bio(techno)logists with a passion for nucleic acid binding proteins and genome editing. Deadline for PhD: Oct 15th
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It has long been recognized that millions of women, especially younger women, are disproportionately affected by pain disorders. In a new #ScienceReview, researchers synthesize recent advances in understanding these conditions. scim.ag/3VcRS4H
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Irma Querques retweeted
Sternberg Lab@SternbergLabMay 12
1/9 New preprint from the Sternberg Lab in collaboration with the Nishimasu Lab! We uncover how the DRT3 antiphage immune system pairs two reverse transcriptases, one RNA-templated and one protein-templated, to build a double-stranded DNA effector. doi.org/10.64898/2026.05.04.…
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Happy to share the first preprint from our lab now online on bioRxiv! Congrats to Mateusz, Giada, Seraina, and all authors (BRAVI!). Great collaboration with the Jinek lab and @SternbergLab biorxiv.org/content/10.64898… @MaxPerutzLabs @univienna
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Congratulations to first author @AritzRoa for his amazing work on how T4 delivers its genome and blocks other phages from injecting theirs 🥳 Check out his beautiful movie📽️ Thanks to all authors and collaborators MLNielsen and @AHarms485 tinyurl.com/2kvva646 #cryoEM #phage
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🔴 Great opportunity to perform a PhD in different labs (including ours) 👇
CIB Margarita Salas (CSIC)@CIB_CSIC4 Dec 2025
#CIBjobOffer 10 research positions available at the First Call of #SYNBIO-CSIC doctoral network for advanced training in Synthetic and Engineering Biology. Deadline: Feb 26, 2026 Documents and detailed steps 🔗lifehub.csic.es/synbio-cofun…
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Irma Querques retweeted
Indra Roux@IndraRoux26 Nov 2025
Excited to share our latest research in @NatureMicrobiol . We uncover hundreds of inhibitory interactions between common chemical pollutants and human gut bacteria. @kiran_r_patil @MRC_TU A thread🧵(1/10) nature.com/articles/s41564-0…
Illustration showing pesticides sprayed on vegetables, reaching gut bacteria, alongside a chip representing machine learning predicting their effects.

ALT Illustration showing pesticides sprayed on vegetables, reaching gut bacteria, alongside a chip representing machine learning predicting their effects.

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"In the end, I have come to realize that being authentic at work is not a weakness, but rather a strength." #ScienceWorkingLife scim.ag/489m6bk
An illustration of a woman wearing an axolotl costume in front of an audience, with text: Embracing my silly side makes me a better scientist. I wish I’d done it sooner

ALT An illustration of a woman wearing an axolotl costume in front of an audience, with text: Embracing my silly side makes me a better scientist. I wish I’d done it sooner

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Wooow
Sam Sternberg@shsternberg17 Oct 2025
New work from @stephentang23 et al. that describes a fascinating set of reverse transcriptases involved in antiviral immunity. They synthesize tandem-repeat cDNAs that resemble telomeres, revealing an unexpected bacterial evolutionary origin of telomerase. Check out the thread!
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Irma Querques retweeted
EMBL@embl14 Oct 2025
EMBL’s 2025 Kendrew alumni award recipient may know how to make fairy tales come true. Irma Querques repurposed the ‘Sleeping Beauty’ transposon as a genetic tool for new therapeutics, particularly against cancer. embl.org/news/people-perspec…
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nature
@Nature29 Sep 2025
Nature research paper: Protecting double Holliday junctions ensures crossing over during meiosis go.nature.com/4ndH6UI

Protecting double Holliday junctions ensures crossing over during meiosis

Nature - Conditional ablation experiments show that key components of the synaptonemal complex protect double Holliday junction recombination intermediates to ensure their resolution into crossover...

nature.com
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Irma Querques retweeted
Patrick Hsu
@pdhsu24 Sep 2025
in her 1983 nobel lecture, barbara mcclintock presciently described the origins of new species as the aftermath of accidental hybridizations stay tuned for tomorrow, as we stand on her shoulders
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Excited to share my talk at the EMBL John Kendrew Award ceremony about what transposons taught me about science, life, and change along the way. Big thanks to my mentors, @embl, and my current scientific home @MaxPerutzLabs 💛 youtu.be/NwIikKS7EWE?si=4s4g…

Irma Querques - 2025 John Kendrew Award Recipient

Irma Querques, who was a predoc at EMBL Heidelberg from 2014 to 201...

youtube.com
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Wrapping up my @ERC_Research-funded @frontiers_media Fellowship at ISTA. In 4.5 months, I gave talks on science journalism, visited Austrian newsrooms, and connected with researchers and journalists from around the world. Grateful for the opportunity and excited for what’s next!
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1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77
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Temperate phages enhance host fitness via RNA-guided flagellar remodeling biorxiv.org/content/10.1101/… #biorxiv_micrbio

Temperate phages enhance host fitness via RNA-guided flagellar remodeling

Bacterial flagella drive motility and chemotaxis while also playing critical roles in host-pathogen interactions, as their oligomeric subunit, flagellin, is specifically recognized by the mammalian...

biorxiv.org
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Hi there! We are lookig for a highly motivated and talented postdoctoral researcher to join our dynamic team starting in 2026. Please see the call for more details! Come on join us! It will be fun! :)
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Excited to share my last major PhD work from the @SternbergLab. We discovered a mechanism that initiates transcription at programmable sites, without requiring promoter sequences - a novel mode of transcription regulation in bacteria.
Sternberg Lab@SternbergLab11 Jun 2025
New pre-print(s) from the Sternberg Lab in collaboration with @LeifuChangLab! We uncover an unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: tinyurl.com/mr3fd493
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Excited to see our work published in @ScienceAdvances! We present RBPseg, a method for structural prediction of #phage receptor-binding proteins. We applied it to diverse tail fibers and validated the predicted structures using #cryoEM. Read here: science.org/doi/10.1126/scia…

RBPseg: Toward a complete phage tail fiber structure atlas

RBPseg enables accurate modeling of tail fiber structure, providing the first comprehensive tail fiber structure atlas.

science.org
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Exited to share that our RBPseg paper has just come out in @ScienceAdvances. Huge cograts to first author @VKleinSousa and co-authors @AritzRoa, @CloudyKielkopf and @sofos112 #phage #cryoEM #ArtificialIntelligence @UCPH_CPR science.org/doi/10.1126/scia…

RBPseg: Toward a complete phage tail fiber structure atlas

RBPseg enables accurate modeling of tail fiber structure, providing the first comprehensive tail fiber structure atlas.

science.org
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What’s it like to be a postdoc at the Vienna BioCenter? Anna Osnato shares her experience from joining the Institute of Molecular Biotechnology. The VIP³ PostDoc Program call is open – apply now for this unique opportunity! training.vbc.ac.at/post-docs… #VBCPostDoc
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