Institute of Molecular Systems Biology at @ETH_en @ETH_DBIOL - Contributors: Members of IMSB
ETH Zurich
Joined January 2012
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A warm welcome to Paola and Kian, our new IMSB members, who started at the beginning of this month. 😊
IMSB_ETH retweeted
Recap on the Leitner group's @IMSB_ETH summary of the contributions of structural mass spectrometry to the characterization of protein-RNA interactions - proteomics, structural biology, biophysics and more!
doi.org/10.1042/EBC20220174
![(A) The experimental apparatus used in the study of cytochrome c, copied from Dharmasiri and Smith (1996) [49]. (B) The static mixer used to study partially folded myoglobin, adapted from Simmons et al. (2003) [50]. (C) The repurposed adjustable capillary mixer, previously used to study enzyme kinetics, attached to a microfluidic device, adapted from Wilson and Konermann (2003) [51]. (D) Experimental setup using a single syringe pump to control the constant flow rate of all three syringes, adapted from Keppel and Weis (2013) [26]. (E) FastHDX thiol-ene microchip apparatus, adapted copied from Svejdal et al. (2019) [52]. (F) Automatic FastHDX prototype by Seetaloo and Philips (2022) [53]. Image adapted from Waters Corporation 2014 Acquity UPLC M-Class with HDX Technology System Guide.](https://pbs.twimg.com/media/Ge2Eaw2WcAAeFCq.png?name=orig)
ALT (A) The experimental apparatus used in the study of cytochrome c, copied from Dharmasiri and Smith (1996) [49]. (B) The static mixer used to study partially folded myoglobin, adapted from Simmons et al. (2003) [50]. (C) The repurposed adjustable capillary mixer, previously used to study enzyme kinetics, attached to a microfluidic device, adapted from Wilson and Konermann (2003) [51]. (D) Experimental setup using a single syringe pump to control the constant flow rate of all three syringes, adapted from Keppel and Weis (2013) [26]. (E) FastHDX thiol-ene microchip apparatus, adapted copied from Svejdal et al. (2019) [52]. (F) Automatic FastHDX prototype by Seetaloo and Philips (2022) [53]. Image adapted from Waters Corporation 2014 Acquity UPLC M-Class with HDX Technology System Guide.
IMSB_ETH retweeted
📢Don't miss our plenary #seminar this week, with Dr. @pedrobeltrao, from @IMSB_ETH-@ETH_en👇
🤝Hosted by @ptck72
Register now!👉shorturl.at/24xXK
#BarcelonaBiomed
IMSB_ETH retweeted
Thank you European Proteomics Association for the JPA Proteome Pioneer Award in recognition for our group's work in this field. The award promotes "the principles of sharing and integrating resources for the development of excellent research" which is something we do strive for.
Here are the 2023 @EuPAProteomics Awardees! They will personally receive their prizes on Oct 22 at #HUPOEuPA2024. Congratulations to
@Sigridvrhlst, Laurent Gatto, @maurinefucito, @pedrobeltrao,
@DemichevLab, @akadfmfm !🥳
Congratulations to the @Picotti_Lab, and lead authors @CathyMarulli and Christian Dörig, for their exciting new paper in @NatureBiotech 🥂
Our paper describing a new method (FLiP-MS) for the global profiling of protein complex dynamics is out @NatureBiotech !
Read here👉: doi.org/10.1038/s41587-024-0…
🔬 Highlights:
- Uses an experimental library of peptide markers integrated with a structural proteomics workflow.
- Probes the assembly state of hundreds of protein complexes simultaneously across conditions directly from whole cell extracts, informing on binding interface occupancy.
- Supports the structural modelling of protein complexes and the design of compounds targeting them
Congratulations to shared first authors @CathyMarulli and Christian Dörig and thanks to our collaborators @LabBarral and @TorstenSchwede lab
@ETH_en #Proteomics #PPIs #SystemsBiology #LiPMS #teammspec #DrugDiscovery
A warm welcome to Marc, Luc, Sara, Gian and Noa, our new IMSB members who started throughout September 2024 😊
IMSB_ETH retweeted
We are beyond proud of our newest @NatureMedicine paper! Using pharmacoscopy & in-silico drug MoA discovery, we show that the antidepressant Vortioxietine is effective in #Glioblastoma primary patient material and in mouse models.
bit.ly/GBM_SL
#PersonalizedMedicine
IMSB_ETH retweeted
Bacteria live very different lives from us, but they too feel the weight of old age. @vilhelmiina_h takes a look at the world of bacterial aging and the molecular mechanisms that affect humans and single-celled organisms alike. asm.social/24V
IMSB_ETH retweeted
I have an open position for a PhD student in molecular microbiology!
The project is about the role of transcription factors during P. aeruginosa infections 🦠🧬.
More details:
imsb.ethz.ch/research/trouil…
Please share!
A warm welcome to Marco Baumann, who started his PhD in the Wollscheid Lab at the beginning of August. 😊
IMSB_ETH retweeted
My lab is searching for a postdoc in microbiology/microbial metabolomics!
Are you a biologist who is secretly realizing you might be a mass spec nerd? If so, I can relate and I'd love to work with you!
Please check out more details here:
jobso.id/j6x1
Congratulations @JulianTrouillon🍾 We look forward to seeing all the great science from your group here at @IMSB_ETH
Congratulations Sammy! We wish you all the best in starting your own group at @BiologyKULeuven and @VIB_microbes 🥂
IMSB_ETH retweeted
We have been hosting Prof. @mike_tilapia from the @DonnellyCentre for a part of his sabbatical in our group at @IMSB_ETH. Here is proof of him doing some actual experiments. He will be around still a few weeks so reach out to him if you are in the area and would like to chat.
We are very happy to have Mikko Taipale @mike_tilapia with us! He is Associate Professor at the Donnelly Centre & the Dep of Molecular Genetics at the University of Toronto and currently our Guest Professor at IMSB 😊
Congratulations to our very own @pedrobeltrao for his election to @EMBO membership 🥳
I am honored to have been elected @EMBO member, a recognition of the work of our fantastic group members over the years. Aligned to EMBO's mission, I remain committed to support life science research through teaching, training and service activities. embo.org/press-releases/outs…
A warm welcome to Angela, Kosuke and Ilaria, our new IMSB members, who started at the beginning of this week. 😊
