Recently, we launched a steroid analysis service in hair/nails. haidut.me/?p=1858 A get a lot of emails asking for a sample report, so here are some screenshots. The layout may change as we continue to add more steroids to the list, but I think it is OK as a first attempt.

PUFA peroxidation byproduct and endotoxin/LPS drive ALS and are reliable predictors of its lethality - [haidut.me/?p=3141] #4HNE, #als, #endotoxin, #inflammation, #lps, #mortality, #PUFA, #tlr4

An estrogen-family receptor (ERRy) drives cancerization, age-related strength decline; blocking ERRy reverses at least the latter - [haidut.me/?p=3139] #aging, #cardiolipin, #ERRy, #estrogen, #mitochondria, #muscle, #ROS, #sarcopenia

Cholesterol is a cellular "lifesaver"; inhibiting its synthesis (e.g. statins) poisons cells through mitochondrial debris and fatty acids - [haidut.me/?p=3137] #cholesterol, #FFA, #lipotoxicity, #lysosome, #membrane, #mitochondria, #mitophagy, #statin

Omega-3 (fish oil) is toxic to the brain and inhibits recovery after traumatic injury (TBI), may cause Alzheimer's - [haidut.me/?p=3134] #alzheimer, #brain, #CTE, #DHA, #EPA, #omega-3, #peroxidation, #PUFA, #tbi

Vitamin B6 (monotherapy) may treat depression - [haidut.me/?p=3131] #cortisol, #depression, #dopamine, #GABA, #glutamate, #p5p, #pyridoxal, #pyridoxine

A flagship "antidepressant" (SSRI) drug worsens depression and is ineffective for anxiety - [haidut.me/?p=3128] #amygdala, #anxiety, #depression, #escitalopram, #lexapro, #serotonin, #SSRI

Age-related inflammation driven by declining OXPHOS, even in the absence of inflammatory mediators/triggers - [haidut.me/?p=3126] #acetylCoA, #aging, #CoA, #DNA, #inflammation, #mitochondria, #RNA, #senescent

Lactate accumulation inside cells inhibits OXPHOS and is sufficient to block (kidney) recovery after injury - [haidut.me/?p=3124] #ischemia, #kidney, #Krebs, #lactate, #LDH, #OXPHOS, #reperfusion, #TCA

Vitamin E ameliorates deep vein thrombosis (DVT) by reducing ferroptosis (cell death due to iron overload) - [haidut.me/?p=3122] #clot, #DVT, #embolism, #ferroptosis, #iron, #mitochondria, #thrombosis, #tocopherol

Niacinamide may alleviate systemic sclerosis (scleroderma) and Raynaud syndrome - [haidut.me/?p=3119] #fibrosis, #nad, #niacinamide, #nicotinamide, #raynaud, #scleroderma, #vascular

The toxicity of cysteine revealed - it causes iron overload in mitochondria and cell death - [haidut.me/?p=3117] #cysteine, #ferritin, #ferroptosis, #glutathione, #GSH, #iron, #mitochondria, #peroxidation

The anti-acid drug famotidine has very similar effects to Meldonium/Mildronate - i.e. inhibits fatty acid oxidation (FAO) - [haidut.me/?p=3114] #bbox, #famotidine, #FAO, #glucose, #meldonium, #mildronate, #OCTN2

Mitochondria produce energy through a quantum effect dependent on infrared light and the "metabolic waste" CO2 - [haidut.me/?p=3111] #atp, #cardiolipin, #co2, #cristae, #mitochondria, #nad, #OXPHOS, #quantum, #infrared

Statins damage muscles by increasing endotoxin/LPS absorption and inhibiting glucose metabolism - [haidut.me/?p=3107] #cholesterol, #endotoxin, #glucose, #inflammasone, #inflammation, #lps, #myopathy, #statin

Intact thymus (a sign of lower cortisol/estrogen exposure) is a very good predictor of health/longevity - [haidut.me/?p=3104] #aging, #cancer, #cortisol, #estrogen, #health, #immunity, #lifespan, #thymus

Interfering with mitochondrial dynamics causes cancer (by driving inflammation); no carcinogen/mutation required! - [haidut.me/?p=3102] #cancer, #FAO, #fission, #fusion, #inflammation, #liver, #mitochondria

Excessive fatty acid oxidation (FAO) drives heart failure by depleting cardiolipin - [haidut.me/?p=3099] #aspirin, #cardiolipin, #cardiomyopathy, #energy, #FAO, #heart, #meldonium, #niacinamide

Blocking the endotoxin/LPS receptor (TLR4) prevents brain damage from concussion - [haidut.me/?p=3097] #brain, #concussion, #endotoxin, #inflammation, #lps, #MMP-9, #tlr4

Eliminating sugar (sucrose) from the diet leads to diabetes, as well as gut and liver inflammation - [haidut.me/?p=3095] #colon, #diabetes, #inflammation, #liver, #low-carb, #nafld, #nash, #sucrose, #sugar

Estrogen drives thyroid cancer in women - [haidut.me/?p=3093] #cancer, #carcinogen, #endocrine, #estrogen, #hrt, #thyroid, #WHI