@guoci
Joined July 2009
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Now online: Long-Read Haplotype Phasing Resolves Allelic Configuration as a Missing Layer of Precision Oncology doi.org/10.1158/2159-8290.CD…
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Long-Read Haplotype Phasing Resolves Allelic Configuration as a Missing Layer of Precision Oncology doi.org/10.1158/2159-8290.CD… medrxiv.org/content/10.64898…

Long-Read Haplotype Phasing Resolves Allelic Configuration as a Missing Layer of Precision Oncology

Abstract. Short-read sequencing cannot determine whether co-occurring variants within a cancer gene lie on the same allele (cis) or opposing alleles (trans), a distinction with direct therapeutic...

aacrjournals.org
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In this work just out in JPR by GuoCi Teo @DanPolasky and @fcyucn we describe a fast MS2 deisotoping algorithm. Implemented in #MSFragger, it reduces the search time and and boosts ID numbers, especially for open, glycopeptide, and peptidome searches. pubs.acs.org/doi/10.1021/acs…

Fast Deisotoping Algorithm and Its Implementation in the MSFragger Search Engine

Abstract. Deisotoping, or the process of removing peaks in a mass spectrum resulting from the incorporation of naturally occurring heavy isotopes, has long

pubs.acs.org
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Scientists present a new, high-speed parallelized deisotoping algorithm based on elements of several existing methods. When applied to MSFragger, this improves database search speed and performance, particularly for complex methods. pubs.acs.org/doi/10.1021/acs…

Fast Deisotoping Algorithm and Its Implementation in the MSFragger Search Engine

Abstract. Deisotoping, or the process of removing peaks in a mass spectrum resulting from the incorporation of naturally occurring heavy isotopes, has long

pubs.acs.org
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At least we're better at what really counts!
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