
ML @RecursionPharma. Previous: ML Engineer @dewpoint_tx @PhenomicAI. Into ML, physics, math, music, computer-generated art, and Dungeons & Dragons.
Toronto, Ontario
Joined August 2017
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Grant Watson retweeted
Autoresearch loops are a particularly promising form of continual learning that we can scale indefinitely over time. However, in practice, they often plateau as runs get longer. In naive implementations of such loops, agents "lose motivation" after seeing full history and talk themselves out of trying anything new.
Stateless Language Agents (SLA) looks at why this happens and proposes a few simple modifications to scale usefully to 1B tokens (!). The core trick is to hide as much context as possible from each worker while having a separate advisor agent handle coordination.
SLA achieves the best final result on every task we tested (vs EvoX, CORAL, SwarmResearch), often by a wide margin!
AutoResearch agents keep burning tokens after they stop making progress. 💰😭
From authors of ACE and Meta-Harness: Introducing Stateless Language Agents (SLAs). Stateful search, stateless agents. Advancing the performance-cost Pareto frontier of RSI.
Across 9 tasks, up to 1B tokens:
- Best final result on every task 📈
- 14.5× fewer tokens to match the best kernel baseline 🚀
- Advisor (the “coordinator”) uses < 0.6% of total tokens 🫣
📑 Paper: arxiv.org/abs/2610.07625
NOT JUST HIGHER NUMBERS. Some more surprising findings in the thread below! 🧵 #LLM #AI #RSI #Agent
Grant Watson retweeted
Great researchers have an uncanny ability to make connections that seem inevitable in hindsight, in places nobody else would have thought to look. Can we measure this ability?
Introducing ScholarCatalyst: a far-from-saturated benchmark for finding what we call "catalyst papers"📚, labeled by 184 lead authors on 207 of their own recent projects.
Paper: arxiv.org/abs/2610.02202
To make sustained progress on open-ended problems, I think agents need the sort of "research taste" that great researchers have. They need to make deep connections between earlier discoveries and problems those discoveries weren't intended to solve. ScholarCatalyst is a first step towards this goal.
More details in the thread below🧵
Grant Watson retweeted
Accepted to #NeurIPS2026, we reshaped Monte-Carlo Tree Search 🙉
Introducing 2FFS, a new tree search algorithm that combines multi-fidelity bandits to resolve the fundamental trade-off: should we use cheaper, approximated evaluations, or expansive but accurate samplings?
More:
Grant Watson retweeted
Can an LM, starting from random init (!!), learn to generate all of its pretraining data?
Introducing Self-Play Pretraining with Zero Data. Two models start from random initialization: a generator proposes programs for a universal Turing machine and a learner trains on their outputs. We never train on any real data, but see predictable scaling on natural datasets: zero-shot val loss on images, text, audio, and melodies decreases predictably with self-play compute. And the learner develops in-context learning capabilities.
A fun proof-of-concept, co-led with @AdityaCowsik and @KfirDolev and co-authors @gbruno_dl, @ANourya @noahdgoodman, and @YoavLevine.
Grant Watson retweeted
“An accumulation of facts is no more a science than a heap of stones is a house.” - Poincaré
LLMs are now proving results that have resisted mathematicians for decades. Finding interesting theorems without human guidance is a new bottleneck. We show that we can teach an LLM to do it!
TL;DR:
→ a quantitative notion of interestingness
→ 4.3× higher interestingness
→ a self-expanding discovery loop
[1/5]
Grant Watson retweeted
Sakana AI welcomes Jürgen Schmidhuber as Chief Scientific Advisor.
sakana.ai/schmidhuber/
Sakana AI is incredibly proud to announce that Jürgen Schmidhuber, universally recognized as the father of modern AI, is officially joining Sakana AI as Chief Scientific Advisor.
For nearly four decades, Jürgen has explored how machines can learn to learn. His foundational work in the 1990s drove core advancements in deep learning and established early frameworks for world models. Crucially, his pioneering innovations in meta-learning opened the very path toward recursive self-improvement.
These ideas have already shaped our own research, from the Darwin Gödel Machine to The AI Scientist. Now Jürgen will help guide our newly formed RSI Lab, whose objective is to trigger a compounding cycle of scientific discovery aimed at improving machine intelligence. We are assembling a critical mass of world-class experts in Tokyo to make this a reality.
Welcome, @SchmidhuberAI !
Grant Watson retweeted
Current LLMs aren't truly creative because they haven't implemented the "Formal Theory of Fun and Creativity" (2008) yet. See "Driven by Compression Progress: A Simple Principle Explains Essential Aspects of Subjective Beauty, Novelty, Surprise, Interestingness, Attention, Curiosity, Creativity, Art, Science, Music, Jokes" arxiv.org/abs/0812.4360 Tweet: xitter.cf/SchmidhuberAI/status/1…
Oxford researchers argue that LLMs can never invent anything.
It is mathematically impossible.
They published a paper called “Theory Is All You Need" and it argues against the claim that computational models can generate genuine novelty or new knowledge.
They analyzed the limits of generative ai, and the results are a brutal reality check for the idea that ai will replace human decision making under uncertainty.
Here is why AI is stuck and human cognition wins:
backward-looking vs forward-looking.. llms are probability machines that look backward at existing data. human cognition is forward-looking and capable of generating genuine novelty. human cognition operates theoretically "top-down" rather than "bottom-up" from data.
the "data-belief asymmetry".. the researchers use the invention of "heavier-than-air flight" to illustrate this concept. an ai relies on data-based prediction, which is largely imitative. humans, however, use theory-based causal logic that allows them to hold beliefs that go beyond existing data.
the intervention gap.. humans don't just process information; we use theory to practically "intervene" in the world. we engage in directed experimentation to generate entirely new data. ai-based models are theory-free and place primacy on existing data and prediction.
tldr?
AI uses a probability-based approach to knowledge and ia largely imitative. It can process data and make predictions, but human cognition relies on theory-based causal reasoning.
The decades-old analogy comparing human minds and computers to mere "input-output" devices is fundamentally flawed.
Grant Watson retweeted
Why should a generative model be diverse? 👀
If there’s an obviously best answer, why put probability on worse ones?
New paper: a perspective on what diversity is *for*, and an algorithm on post-training for the right amount 🌹.
🧵🔽 [1/12]
Grant Watson retweeted
Our group discovered that reasoning models produce fractals when asked to solve hard problems. We can use nonlinear dynamics to probe the thinking processes of recurrent depth models on Sudoku, mathematics, and even ARC-AGI (1/N)
arxiv.org/abs/2609.04963
Grant Watson retweeted
Predicting the answer to interventional "what if?" questions — the outcome of an action you never took — need a *mechanistic* model, not a curve fit. And you can only learn one by *experimenting*. Experiments are costly, so the real game is **data efficiency**.
Meet the Model Discovery Agent (MDA). 🧵
I am excited to share some of the progress we are making towards using Gemini to accelerate scientific discovery in the real-world.
We present an extension of Co-Scientist that transitions from pure in silico ideation to execution-grounded research partner, adapting to multiple levels of autonomy across different scientific domains.
Grant Watson retweeted
One of the puzzles in perturbation prediction, and the cause of many food fights, is that deep learning models often lose to the simplest possible baseline-- just predict the average response across all perturbations.
This summer, multiple labs converged on an answer to this.
Grant Watson retweeted
I ran Boltz-2 100 million times 🤯
A cell is shaped by billions of interactions between proteins, RNA, DNA and small molecules. Co-folding can now simulate some of these interactions at scale.
So what can we do with all this data?
Could it open a bottom-up path to Virtual Cells?
Can it help us understand the limitations of co-folding models? And learn when they actually translate to biology?
🧵
Grant Watson retweeted
Tackling a 60-year-old challenge in quantum chemistry: making density functional theory scale nearly linearly with system size.
This has huge implications for opening the door to realistic systems that have traditionally been too expensive to simulate.
AI has attempted to accelerate these calculations, but models generally struggle to extrapolate, particularly to systems larger than those seen during training. Unlike text or images, quantum-mechanical training data is extremely expensive to generate.
We present a single unified AI model that performs quantum-mechanical simulations of both molecules and materials in quasi-linear time.
Using a novel Fourier neural operator variant, we learn the underlying Kohn–Sham equation map to produce physics-informed, self-consistent answers.
Unlike prior AI approaches that directly predict chemical properties, our model works through intermediate steps to improve difficult predictions, resembling inference-time reasoning in large language models.
To demonstrate its scalability, we run a self-consistent calculation of a magnesium dislocation with about 80k electrons on a single GPU, which previously required about 7k GPUs.
tensorlab.cms.caltech.edu/us…
@DanishK42 @Caltech
Grant Watson retweeted
Continuous self-improvement needs an ever-expanding supply of training environments (goals).
SPADE: one model self-plays the Environment Designer and the Reasoning Agent, writing executable, agentic environments that get harder as it improves. Environment scaling on its own. ♠️
Grant Watson retweeted
New work I'm very excited about: Physics of Agents!🤖
As AI agents become more prevalent, they'll interact and influence one another.
Can we predict the collective behavior that emerges?
Surprisingly, their dynamics follow compact, predictive laws of statistical physics🧵
Grant Watson retweeted
Today we’re sharing an update on Claude’s protein design capabilities.
Working with Adaptyv Bio and Twist Bioscience, Claude designed de novo protein binders against 14 of 15 targets. With a 30k token prompt written by a human expert, Claude achieved hit rates up to 28.2% when designing against all targets simultaneously over 48 hours, with no human intervention or steering. When designing against a single target in a 24 hour campaign, Claude achieved an overall hit rate of 35%.
We included all targets in Adaptyv’s BenchBB, and novel targets 15-PGDH and GDF-8. Claude performs at or beyond the level of the top competition participants in both hit rate and binding affinity.
Grant Watson retweeted
Rigid, hand-designed sampling schedules become inaccurate during autoregressive video generation as errors accumulate.
We introduce Equilibrium Forcing (EqF), a modular framework for video generative modeling that removes noise level conditioning to enable adaptive inference. 🌀





































